Anusol-HC Coupons & Prices

Hydrocortisone Acetate

Anusol-HC is a prescription topical cream and rectal suppository. The topical cream relieves swelling, itching, and redness of the skin produced by a variety of causes. Anusol-HC suppositories treat the symptoms of hemorrhoids and other problems of the anus, such as itching or fissures. The active ingredient in Anusol-HC, hydrocortisone acetate, reduces swelling and so relieves the itching, redness, and discomfort of the underlying condition. Anusol-HC costs $896.94 for 1, 12 suppository box, but a SingleCare Anusol-HC coupon brings that price down to $19.99 for 1, 30gm of 2.5% tube of cream of generic Anusol-HC at participating pharmacies.

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Anusol-HC coupon at Costco Pharmacy
$ 19.99

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Anusol-HC coupon at Food Lion Pharmacy
$ 21.13

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Anusol-HC coupon at Publix Pharmacy
$ 22.45
Anusol-HC coupon at CVS Pharmacy
$27.72
$ 24.72
$3 off with signupwith signup
Anusol-HC coupon at Walmart Neighborhood Market Pharmacy
$33.32
$ 30.32
$3 off with signupwith signup
Anusol-HC coupon at Walmart Pharmacy
$33.32
$ 30.32
$3 off with signupwith signup
$35.09
$ 32.09
$3 off with signupwith signup
$51.99
$ 48.99
$3 off with signupwith signup
$51.99
$ 48.99
$3 off with signupwith signup

About SingleCare Pricing

SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.

Any SingleCare bonus savings, including the $3 signup bonus, may only be used once.

Prices updated: 12/05/2025

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About Anusol-HC

Anusol-HC is a prescription topical cream and rectal suppository. The topical cream relieves swelling, itching, and redness of the skin produced by a variety of causes. Anusol-HC suppositories treat the symptoms of hemorrhoids and other problems of the anus, such as itching or fissures. The active ingredient in Anusol-HC, hydrocortisone acetate, reduces swelling and so relieves the itching, redness, and discomfort of the underlying condition. Anusol-HC costs $896.94 for 1, 12 suppository box, but a SingleCare Anusol-HC coupon brings that price down to $19.99 for 1, 30gm of 2.5% tube of cream of generic Anusol-HC at participating pharmacies.

Anusol-HC Price History & Information

Price History for Anusol-Hc (Trademark Generic) & Hydrocortisone Acetate (Generic)

1 count, box, 12 suppository

Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.

Average 1-Month Prices for Anusol-Hc (Trademark Generic) & Hydrocortisone Acetate (Generic)

1 count, box, 12 suppository
PharmacyAnusol-Hc Retail PriceHydrocortisone Acetate Retail PriceHydrocortisone Acetate SingleCare Price
CVS Pharmacy$77.40$77.40$76.80
Walmart-$269.30$53.90
Walgreens$2288.47$411.63$217.31
Kroger Pharmacy$2498.10$358.98$317.82
Albertsons Pharmacy-$526.20$65.70

These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.

About Anusol-HC

Anusol-HC is a prescription topical cream and rectal suppository. The topical cream relieves swelling, itching, and redness of the skin produced by a variety of causes. Anusol-HC suppositories treat the symptoms of hemorrhoids and other problems of the anus, such as itching or fissures. The active ingredient in Anusol-HC, hydrocortisone acetate, reduces swelling and so relieves the itching, redness, and discomfort of the underlying condition. Anusol-HC costs $896.94 for 1, 12 suppository box, but a SingleCare Anusol-HC coupon brings that price down to $19.99 for 1, 30gm of 2.5% tube of cream of generic Anusol-HC at participating pharmacies.

Anusol-HC FAQs

How much does Anusol-HC cost without insurance?

A prescription will cost around $896.94 for uninsured customers. With a SingleCare discount card, the price for Anusol-HC will only be $19.99 for 1, 30gm of 2.5% tube of cream of generic Anusol-HC.

How much does Anusol-HC cost with insurance?

the copay cost of Anusol-HC with insurance varies by plan. With a SingleCare savings card, Anusol-HC costs $19.99 for 1, 30gm of 2.5% tube of cream of generic Anusol-HC. This may be a better alternative to insurance, so have your pharmacist compare prices with your SingleCare Anusol-HC coupon first before you overpay for Anusol-HC.

Does Medicare cover Anusol-HC and how much does it cost?

Medicare-eligible patients are unlikely to be covered for their Anusol-HC cream or Anusol-HC suppository prescription. Medicare-eligible patients can save money with SingleCare Anusol-HC coupons – the price of Anusol-HC with a SingleCare is only $19.99 for 1, 30gm of 2.5% tube of cream of generic Anusol-HC.

Is there a generic of Anusol-HC?

Anusol-HC is a brand-name prescription skin cream or rectal suppository with 2.5% hydrocortisone acetate. Generic hydrocortisone acetate cream is supplied by generic manufacturers such as Crown, Sebela, and Taro. Generic hydrocortisone acetate suppositories are available from Nucare, Paddock, and other generic manufacturers.

What is Anusol-HC?

Anusol-HC is a prescription skin cream or rectal suppository that treats skin inflammation, irritation, redness, and itching (i.e., Anusol-HC cream) or hemorrhoid symptoms, anal itching, or irritation and swelling due to anal fissures (i.e, Anusol-HC suppositories).

Anusol-HC suppositories are also used to treat anal and rectal injury due to radiation therapy and to relieve the pain of rectal sores due to ulcerative colitis (swelling and sores in the colon and rectum).

The active ingredient in Anusol-HC, hydrocortisone acetate, is a synthetic steroid that belongs to a class of drugs called corticosteroids. Hydrocortisone activates cells into manufacturing proteins that block the immune system's production of chemicals that cause swelling and irritation. By reducing swelling, Anusol-HC relieves irritation, pain, itching, and soreness caused by swelling.

As a cream, Anusol-HC is applied to the affected area two to four times a day. As a suppository, Anusol-HC is administered twice per day, morning and evening, for two weeks.

What are the side effects of Anusol-HC?

The most common side effects of Anusol-HC are irritation, stinging, burning, rash, itching, and other allergic reactions. Hydrocortisone cream may also cause pimples, loss of skin pigmentation, thinning of the skin, swollen hair follicles, and stretch marks. Hydrocortisone suppositories may cause rectal burning, rectal pain, rectal bleeding, or black, tarry stools. Damage to the rectal wall because of improper insertion of the suppository is common.

This is not a complete list of side effects and others may occur. If you have questions about side effects, consult with your doctor or pharmacist.

Where are Anusol-HC coupons from SingleCare accepted?

SingleCare is accepted at most national pharmacies and grocers, including the following:

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