Xeljanz is a prescription drug used to treat adults with moderate to severe rheumatoid arthritis or active psoriatic arthritis. This brand-name drug is also used to treat adults with ankylosing spondylitis or ulcerative colitis and children with juvenile idiopathic arthritis. The active ingredient of Xeljanz is tofacitinib. Xeljanz costs around $7,497.47 for 60, 5mg tablets but luckily you can reduce the price of Xeljanz to $5,455.32 for 60, 5mg tablets by using our SingleCare coupons. Talk to your pharmacist at your local pharmacy or specialty pharmacy about using SingleCare coupons for Xeljanz.
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Prices updated: 12/18/2025
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Xeljanz is a prescription drug used to treat adults with moderate to severe rheumatoid arthritis or active psoriatic arthritis. This brand-name drug is also used to treat adults with ankylosing spondylitis or ulcerative colitis and children with juvenile idiopathic arthritis. The active ingredient of Xeljanz is tofacitinib. Xeljanz costs around $7,497.47 for 60, 5mg tablets but luckily you can reduce the price of Xeljanz to $5,455.32 for 60, 5mg tablets by using our SingleCare coupons. Talk to your pharmacist at your local pharmacy or specialty pharmacy about using SingleCare coupons for Xeljanz.
Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.
These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.
Xeljanz is a prescription drug used to treat adults with moderate to severe rheumatoid arthritis or active psoriatic arthritis. This brand-name drug is also used to treat adults with ankylosing spondylitis or ulcerative colitis and children with juvenile idiopathic arthritis. The active ingredient of Xeljanz is tofacitinib. Xeljanz costs around $7,497.47 for 60, 5mg tablets but luckily you can reduce the price of Xeljanz to $5,455.32 for 60, 5mg tablets by using our SingleCare coupons. Talk to your pharmacist at your local pharmacy or specialty pharmacy about using SingleCare coupons for Xeljanz.
The average retail price of Xeljanz is about $7,497.47. You can use Xeljanz coupons below for a reduced cost on Xeljanz and pay a discounted price as low as $5,455.32 for 60, 5mg tablets. Ask your specialty pharmacy or local pharmacy for more pricing information.
The average copay for Xeljanz varies by health insurance company but with SingleCare. You can pay $5,455.32 for 60, 5mg tablets. Speak to your pharmacist about using your SingleCare Savings card to compare prices to get the best possible deal on your next refill. You can always contact your insurance provider for up-to-date insurance coverage information.
Medicare Part D and Medicare Advantage Plans typically cover this drug. Refer to your plan’s drug formulary to determine the copay or coinsurance amount. You can pay $5,455.32 for 60, 5mg tablets when using your SingleCare discount card or coupon as this may sometimes be cheaper than your health insurance coverage.
Check the Xeljanz manufacturer website for current savings and support programs. To save on Xeljanz, you can use our SingleCare coupons or discount card to pay as little as $5,455.32 for 60, 5mg tablets. Access the SingleCare website and start saving today.
Tofacitinib is the active ingredient of Xeljanz, but a generic version is not available. Xeljanz is the brand name. Check SingleCare for coupons on this prescription medication.
Xeljanz is a prescription drug in the Janus kinase (JAK) inhibitor drug class. It treats adults with moderate to severe rheumatoid arthritis, active psoriatic arthritis, moderate to severe ulcerative colitis, or ankylosing spondylitis. It can also be used to treat children with juvenile idiopathic arthritis. Xeljanz is generally used when other medications have not worked or cannot be tolerated.
There is also an extended-release version of Xeljanz called Xeljanz XR. Taken orally, Xeljanz blocks the activity of certain enzymes in the body that can affect the function of your immune system. Follow your healthcare provider’s dosage instructions.
It is important that you inform your healthcare provider if you are using any of the following medications: fluconazole, ketoconazole, methotrexate, rifampin, or any other medicines when using Xeljanz that affect your immune system (including azathioprine, cyclosporine, tacrolimus). You should also avoid grapefruit juice and other grapefruit products while taking Xeljanz.
Taking Xeljanz can increase the risk of life-threatening medical problems, including serious infections, cancer, blood clots, heart attack, stroke, and holes or tears in the digestive tract.
It is important to note that you should not use Xeljanz if you have a serious infection or severe liver disease.
Tell your healthcare provider if you smoke, as well as about any medical conditions, you have or have ever had, including:
Diabetes
Stomach or intestinal problems such as diverticulitis or ulcers
Cancer
Kidney transplant
Heart problems including heart attack, stroke, or blood clots
Hepatitis B or C
Tuberculosis (or if anyone in your household has tuberculosis)
Shingles
HIV
A weakened immune system
Lung disease
The risk of developing certain cancers such as lymphoma, lung cancer, or skin cancer can increase when using Xeljanz. It is also important to tell your healthcare provider if you are pregnant or planning to become pregnant.
Xeljanz should be stored at room temperature. Keep out of reach and out of sight of children and pets.
Rheumatoid arthritis: In one study, adults with moderate to severe rheumatoid arthritis (RA) that could not tolerate other prescription medications (or other medications were not effective) received Xeljanz or placebo (inactive medicine). After 3 months, 59% of people who took Xeljanz reported an improvement in RA symptoms. Many patients reported they could more easily complete daily activities such as getting dressed and had less joint pain and swelling.
Psoriatic arthritis: A study in adults with psoriatic arthritis concluded that Xeljanz reduced joint pain and swelling by two weeks, although for some patients, results took up to 6 months. Half of the people who took Xeljanz reported less joint pain and swelling at 3 months, and 68% reported less joint pain and swelling at the one-year mark.
Ulcerative colitis: In a study of adults with moderate to severe ulcerative colitis, some patients reported less rectal bleeding and stool frequency at two weeks. Eighteen percent of people who took Xeljanz achieved remission at 8 weeks. Forty one percent of people who took Xeljanz 10 mg twice daily and 34% of those who took 5 mg twice daily were in remission at one year.
Because results vary, it is important to talk to your doctor about the benefits and risks before taking this medication.
Patients being treated with Xeljanz may be susceptible to serious infections causing hospitalization or death. Tuberculosis and bacterial, invasive fungal, viral and other opportunistic infections have occurred in patients using Xeljanz. Should a serious infection develop, you should talk to your healthcare provider about discontinuing Xeljanz until the infection is controlled and alleviated.
You should seek emergency medical attention immediately if you experience any allergic reaction such as hives, difficulty breathing, or swelling of the face, lips, throat, or tongue. You should also get emergency medical help if you experience sudden shortness of breath, chest pain that spreads to the neck or arms, nausea, severe dizziness, a cold sweat, weakness on one side of the body, slurred speech, or pain, redness, or swelling in an arm or leg.
Notify your healthcare provider immediately if you have a fever, night sweats, tiredness, weight loss, abdominal pain, diarrhea, wheezing, severe cough, or lumps in the neck, armpits, or groin.
This is not a complete list of all possible side effects. Talk to your healthcare provider before using Xeljanz to determine if it is right for you.
Both medications can effectively treat symptoms of conditions such as rheumatoid arthritis and others. However, each medication has a list of potential side effects, including serious ones, that must be considered. Consult your healthcare provider for medical advice and more information about Humira or Xeljanz. Only your healthcare provider can determine which medication is more appropriate for you.
After receiving her doctorate from the University of Pittsburgh School of Pharmacy, Karen Berger, Pharm.D., has worked in both chain and independent community pharmacies. She currently works at an independent pharmacy in New Jersey. Dr. Berger enjoys helping patients understand medical conditions and medications—both in person as a pharmacist, and online as a medical writer and reviewer.
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SingleCare is a prescription discount service that offers free coupons on thousands of prescription drugs. It can be used whether you have insurance, Medicare, Medicaid, or none of the above, but it cannot be combined with insurance.
SingleCare provides transparent drug pricing, so you can compare discounts at pharmacies near you. Browse singlecare.com to find drug discounts, helpful information about your prescription, and resources to help you make informed health decisions.
Prescription savings vary by prescription and by pharmacy, and may reach up to 80% off cash price. This is a medical discount plan. This is NOT insurance. This program offers you the opportunity to locate providers of various types of medical services who will offer their services to you at discounted rates. The range of discounts for medical or ancillary services provided under the plan will vary depending on the type of provider and service received. You are fully responsible for paying for all health care services but will be entitled to receive a discount from those health care providers in accordance with the specific pre-negotiated discounted fee schedule. This program does not guarantee the quality of the services or procedures offered by the providers. Except for prescription drugs which you will pay directly to the pharmacy at the time of purchase, all other services received through a program provider will be charged to the credit card on file in your member account. The charge will include an administrative fee for use of the program. Towers Administrators LLC is the licensed discount medical plan organization with its administrative office located at 4510 Cox Road, Suite 111, Glen Allen, VA 23060. SingleCare Services, LLC is the marketer of the discount medical plan organization including its website, singlecare.com, with its corporate office located at 99 High Street, Suite 2800, Boston, MA 02110. For additional information, including an up-to-date list of providers, or assistance with any issue related to program membership, please contact member support any time at www.singlecare.com, or by calling toll-free 844-234-3057, 24 hours, 7 days a week (except major holidays). Pharmacy names, logos, brands, and other trademarks are the property of their respective owners.
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© 2025 SingleCare Administrators. All rights reserved