Aprepitant is an FDA approved generic prescription drug that is used to prevent nausea caused by chemotherapy treatment. Aprepitant blocks the binding of a certain chemical called substance P to NK1 receptors, which are involved with the brain's vomiting center. Aprepitant is the active ingredient in the brand-name prescription drug, Emend. It is available as an oral capsule. The retail price for generic Aprepitant is $170.84, but a free coupon from SingleCare may be able to reduce the total cost of the drug to $47.07 at participating pharmacies, such as Walgreens, Walmart, Kroger, and CVS pharmacy.
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SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.
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Prices updated: 12/05/2025
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Aprepitant is an FDA approved generic prescription drug that is used to prevent nausea caused by chemotherapy treatment. Aprepitant blocks the binding of a certain chemical called substance P to NK1 receptors, which are involved with the brain's vomiting center. Aprepitant is the active ingredient in the brand-name prescription drug, Emend. It is available as an oral capsule. The retail price for generic Aprepitant is $170.84, but a free coupon from SingleCare may be able to reduce the total cost of the drug to $47.07 at participating pharmacies, such as Walgreens, Walmart, Kroger, and CVS pharmacy.
Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.
| Pharmacy | Aprepitant Retail Price | Aprepitant SingleCare Price |
|---|---|---|
| CVS Pharmacy | $103.99 | $97.07 |
| Walmart | $167.10 | $109.48 |
| Walgreens | $110.99 | $33.06 |
| Kroger Pharmacy | $128.86 | $59.72 |
These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.
Aprepitant is an FDA approved generic prescription drug that is used to prevent nausea caused by chemotherapy treatment. Aprepitant blocks the binding of a certain chemical called substance P to NK1 receptors, which are involved with the brain's vomiting center. Aprepitant is the active ingredient in the brand-name prescription drug, Emend. It is available as an oral capsule. The retail price for generic Aprepitant is $170.84, but a free coupon from SingleCare may be able to reduce the total cost of the drug to $47.07 at participating pharmacies, such as Walgreens, Walmart, Kroger, and CVS pharmacy.
You may pay an average cash price of $170.84 for 1, 40mg capsule of Aprepitant without insurance. However, you could pay only $47.07 with a SingleCare Aprepitant coupon. The quantity and strength prescribed by your doctor could affect the price you pay for Aprepitant.
Aprepitant copay pricing may vary depending on your insurance plan and the quantity prescribed. With SingleCare, Aprepitant costs $47.07, so you should ask your pharmacist to compare your SingleCare price with your insurance copay. A SingleCare savings card typically saves you up to 80% off on your prescription drugs, which may give you a better Aprepitant price than your copay.
Aprepitant may be covered by Medicare prescription drug plans. However, if it is administered in a hospital or clinic to relieve nausea after surgery, Aprepitant and its brand-name versions may be covered under Medicare Part B. For patients without coverage, a SingleCare Aprepitant coupon could help lower the out-of-pocket cost of the medication. With a SingleCare prescription discount card, the price of Aprepitant is only $47.07.
Aprepitant is a generic prescription drug that is also available as a brand-name prescription drug. Emend, manufactured by Merck, is available as an oral capsule or oral powder for suspension. Cinvanti, manufactured by Heron Therapeutics, is an injectable form of Aprepitant. Generic Aprepitant capsules are available from different manufacturers such as Sandoz and Glenmark. Search the SingleCare website or app for Emend or Cinvanti to find more information and potential savings opportunities.
Aprepitant is a prescription drug that prevents nausea due to surgery or chemotherapy treatment. Aprepitant oral capsules can be prescribed to adults and children aged 12 years and older. Treatment is administered before receiving chemotherapy. Aprepitant is not used to treat established nausea or vomiting.
Aprepitant blocks a chemical called substance P that directly triggers the brain's nausea response. Aprepitant is administered as a capsule, oral suspension, or injection. Aprepitant is typically used in combination with other drugs, such as dexamethasone.
The side effects of Aprepitant will depend on how Aprepitant is administered and in what dose. The side effects of Aprepitant include, but are not limited to, fatigue, stomach pain, indigestion, diarrhea, constipation, headache, dizziness, cough, hiccups, dry mouth, gas, and weakness. Tell your doctor or healthcare provider if you experience side effects or if side effects persist or worsen.
Serious side effects may include liver problems and decreased white blood cell counts, which can make patients more susceptible to infections. Mental and mood changes that occur as a result of using Aprepitant are rare, but may include anxiety. Allergic reactions are not common, but you should seek medical attention and discontinue using Aprepitant if you experience rash, swelling, or trouble breathing.
You should consult with your prescribing physician or healthcare professional about other possible side effects, warnings, drug interactions, and medical advice before using Aprepitant.
Gerardo Sison, Pharm.D., graduated from the University of Florida. He has worked in both community and hospital settings, providing drug information and medication therapy management services. As a medical writer, he hopes to educate and empower patients to better manage their health and navigate their treatment plans.
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Prescription savings vary by prescription and by pharmacy, and may reach up to 80% off cash price. This is a medical discount plan. This is NOT insurance. This program offers you the opportunity to locate providers of various types of medical services who will offer their services to you at discounted rates. The range of discounts for medical or ancillary services provided under the plan will vary depending on the type of provider and service received. You are fully responsible for paying for all health care services but will be entitled to receive a discount from those health care providers in accordance with the specific pre-negotiated discounted fee schedule. This program does not guarantee the quality of the services or procedures offered by the providers. Except for prescription drugs which you will pay directly to the pharmacy at the time of purchase, all other services received through a program provider will be charged to the credit card on file in your member account. The charge will include an administrative fee for use of the program. Towers Administrators LLC is the licensed discount medical plan organization with its administrative office located at 4510 Cox Road, Suite 111, Glen Allen, VA 23060. SingleCare Services, LLC is the marketer of the discount medical plan organization including its website, singlecare.com, with its corporate office located at 99 High Street, Suite 2800, Boston, MA 02110. For additional information, including an up-to-date list of providers, or assistance with any issue related to program membership, please contact member support any time at www.singlecare.com, or by calling toll-free 844-234-3057, 24 hours, 7 days a week (except major holidays). Pharmacy names, logos, brands, and other trademarks are the property of their respective owners.
Blog articles are not medical advice. They are intended for general informational purposes and are not meant to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. If you think you may have a medical emergency, immediately call your physician or dial 911.
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© 2025 SingleCare Administrators. All rights reserved