Arixtra Coupons & Prices

Arixtra (fondaparinux) is an FDA-approved prescription injection that prevents blood clots in patients undergoing hip, knee, or abdominal surgery. All of these procedures significantly increase the risk of a blood clot forming and then traveling to  the lungs. Arixtra, in combination with warfarin, also treats deep vein and lung blood clots right after they been diagnosed. The retail price of Arixtra is $189.60. However, you can use SingleCare's Arixtra coupon to save money and pay $58.84. SingleCare prescription discount cards are accepted at your favorite pharmacies.

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Arixtra coupon at CVS Pharmacy
$61.84
$ 58.84
$3 off with signupwith signup

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Arixtra coupon at Walgreens Pharmacy
$148.04
$ 145.04
$3 off with signupwith signup

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Arixtra coupon at Publix Pharmacy
$282.29
$ 279.29
$3 off with signupwith signup
Arixtra coupon at Kroger Pharmacy
$413.79
$ 410.79
$3 off with signupwith signup
Arixtra coupon at Harris Teeter Pharmacy
$413.79
$ 410.79
$3 off with signupwith signup

About SingleCare Pricing

SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.

Any SingleCare bonus savings, including the $3 signup bonus, may only be used once.

Prices updated: 12/18/2025

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About Arixtra

Arixtra (fondaparinux) is an FDA-approved prescription injection that prevents blood clots in patients undergoing hip, knee, or abdominal surgery. All of these procedures significantly increase the risk of a blood clot forming and then traveling to  the lungs. Arixtra, in combination with warfarin, also treats deep vein and lung blood clots right after they been diagnosed. The retail price of Arixtra is $189.60. However, you can use SingleCare's Arixtra coupon to save money and pay $58.84. SingleCare prescription discount cards are accepted at your favorite pharmacies.

Arixtra Price History & Information

Price History for Arixtra (Brand) & Fondaparinux Sodium (Generic)

10 count, syringe, 0.5ml of 2.5mg/0.5ml

Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.

Average 1-Month Prices for Arixtra (Brand) & Fondaparinux Sodium (Generic)

10 count, syringe, 0.5ml of 2.5mg/0.5ml

These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.

About Arixtra

Arixtra (fondaparinux) is an FDA-approved prescription injection that prevents blood clots in patients undergoing hip, knee, or abdominal surgery. All of these procedures significantly increase the risk of a blood clot forming and then traveling to  the lungs. Arixtra, in combination with warfarin, also treats deep vein and lung blood clots right after they been diagnosed. The retail price of Arixtra is $189.60. However, you can use SingleCare's Arixtra coupon to save money and pay $58.84. SingleCare prescription discount cards are accepted at your favorite pharmacies.

Arixtra FAQs

Medically reviewed by Karen BergerPharm.D.
Licensed Pharmacist

How much does Arixtra cost without insurance?

On average, uninsured customers can expect to pay a cash price of $189.60 for an Arixtra prescription. However, $58.84 per 10, 0.5ml of 2.5mg/0.5ml syringes is all you pay per prescription fill with a free coupon from SingleCare. Arixtra may be available through your local pharmacy, or you may need to use a specialty pharmacy, depending on your insurance. 

How much does Arixtra cost with insurance?

Arixtra copays vary by insurance plan and the dose prescribed. If your Arixtra is administered by a healthcare professional, it may be covered as a medical benefit rather than a prescription drug. With a free discount coupon from SingleCare, Arixtra costs $58.84, which may be lower than your insurance copay if you have a prescription for Arixtra. Ask your pharmacist to compare your copay cost to the pricing of Arixtra with SingleCare so that you can pay the lowest price.

Does Medicare cover Arixtra and how much does it cost?

Arixtra and its generic, fondaparinux, are prescription injections that may be given by your doctor, or you may be trained to administer the injection to yourself. Check with your insurance plan regarding Arixtra coverage under  Medicare Advantage and Medicare Part D prescription drug plans  (or its generic, fondaparinux). For Medicare patients, a SingleCare Arixtra coupon offers significant prescription savings at major pharmacies: CVS, Target, Walgreens, and many others.

Is there a generic of Arixtra?

Arixtra is a brand-name prescription injection and is available as a generic injection, fondaparinux, from well-known generic manufacturers such as Sandoz, Zydus, and Aurobindo.

What is Arixtra?

Arixtra (fondaparinux) is a prescription injection that prevents blood clots in patients undergoing hip, knee, or abdominal surgery. All of these procedures significantly increase the risk of deep vein thrombosis (DVT: a blood clot forming and then clogging a deep vein, typically in the leg) or a pulmonary embolism (PE: a blood clot that travels to the lungs). Arixtra is also used (in combination with warfarin) to treat deep vein thrombosis and pulmonary embolism right after they have been diagnosed.

The active ingredient in Arixtra, fondaparinux, is an anticoagulant that prevents blood clotting.

Arixtra is started 6 to 8 hours after surgery or within three days of a DVT or PE diagnosis and continued daily for five to nine days. Arixtra is an injection that must be injected beneath the skin and never into the muscles. For this reason, Arixtra is usually administered by a healthcare professional. In cases where the patient has been trained in self-injection, Arixtra is prescribed and can be purchased as a prescription drug in a pharmacy.

What are the side effects of Arixtra?

Before using Arixtra, talk to your doctor about what side effects to expect and how to address them. Tell your doctor about your medical history and all of the medications you take. This includes prescription and over-the-counter drugs as well as supplements and vitamins. 

Arixtra prevents blood from clotting, so the most common side effects of Arixtra are bleeding problems: anemia, bruising, nosebleeds, gum bleeds, bleeding from wounds or cuts, bloody stools, blood in the urine, and heavy menstrual bleeding. 

Injection site reactions like bleeding, itching, or rash may occur. 

The most serious side effects are complications due to bleeding. Mental and mood changes include confusion. 

Patients who take Arixtra and receive neuraxial anesthesia or who are undergoing a spinal puncture are at higher risk for epidural or spinal hematoma which may result in long-term or permanent paralysis. Certain patients are at higher risk. Consult your doctor before scheduling a spinal procedure. 

Serious allergic reactions are rare. Symptoms include rash, hives, swelling, or trouble breathing. If you have symptoms of an allergic reaction, seek emergency medical help right away. 

This is not a complete list of possible side effects. Your physician should be able to address all your concerns about side effects before you take Arixtra.

Talk to your doctor or healthcare professional for additional information and medical advice.

Medically reviewed by Karen BergerPharm.D.
Licensed Pharmacist

After receiving her doctorate from the University of Pittsburgh School of Pharmacy, Karen Berger, Pharm.D., has worked in both chain and independent community pharmacies. She currently works at an independent pharmacy in New Jersey. Dr. Berger enjoys helping patients understand medical conditions and medications—both in person as a pharmacist, and online as a medical writer and reviewer.

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Where are Arixtra coupons from SingleCare accepted?

SingleCare is accepted at most national pharmacies and grocers, including the following:

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