Key takeaways
Eliquis is a brand-name blood thinner used to prevent or treat blood clots and reduce the risk of stroke in certain people.
Many commercial insurance, Medicare Part D, and Medicaid plans cover Eliquis, but coverage and out-of-pocket costs vary.
Without insurance, Eliquis can be expensive, but using SingleCare coupons, comparing pharmacy prices, or finding lower-cost alternatives with a healthcare provider may help reduce costs.
Eliquis (apixaban) is a brand-name prescription blood thinner or anticoagulant used to prevent or treat blood clots and reduce the risk of stroke in certain people with atrial fibrillation. Eliquis costs about $375 for 28, 5 mg tablets without insurance. Although generic apixaban has received FDA approval, it is not currently available in U.S. pharmacies. However, SingleCare coupons and other savings options may lower the cost.
Save up to 80% on Eliquis with SingleCare
Different pharmacies offer different prices for the same medication. SingleCare helps find the best price for you.
RELATED: What is Eliquis?
How much does Eliquis cost without insurance?
The Eliquis 5 mg price without insurance is around $375 for 28 tablets, or about $14 per tablet. For someone prescribed 5 mg twice daily, 28 tablets is a 14-day supply and costs about $27 per day. Eliquis dosing varies depending on the condition being treated, such as atrial fibrillation, deep vein thrombosis, or pulmonary embolism, as well as personal factors. For people with insurance, out-of-pocket costs vary by plan and coverage details.
Some Eliquis alternatives may cost less. Depending on the condition, a healthcare provider may recommend another anticoagulant, such as warfarin, Arixtra (fondaparinux), or Pradaxa (dabigatran). These medications are approved for some, but not all, of the same uses as Eliquis. Warfarin often costs less but requires regular INR blood tests, which may add to the overall cost.
Although the FDA has approved generic apixaban, it is not currently available in U.S. pharmacies and is not expected to become available until at least 2028.
RELATED: What is the average cost of a 30-day supply of Eliquis?
| Compare the cost of Eliquis with other anticoagulants | |||
|---|---|---|---|
| Drug name | Price without insurance | SingleCare price | Savings options |
|
Direct factor Xa inhibitors |
|||
| Eliquis (apixaban) | $375 for 28, 5 mg tablets | $156 for 28, 5 mg tablets of brand-name Eliquis at Kroger | See latest prices |
| Xarelto
(rivaroxaban) |
$805 for 60, 2.5 mg tablets | $33 for 60, 2.5 mg tablets of generic Xarelto at CVS Pharmacy | See latest prices |
| Savaysa
(edoxaban) |
$567 for
30, 60 mg tablets |
$478 for
30, 60 mg tablets of brand-name Savaysa at Kroger |
See latest prices |
|
Indirect factor Xa inhibitors |
|||
| Arixtra (fondaparinux sodium) | $190 for 10 single-dose 0.5 mL prefilled syringes of 2.5 mg/0.5 mL | $61 for 10 single-dose 0.5 mL prefilled syringes of 2.5 mg/0.5 mL generic Arixtra at CVS Pharmacy | See latest prices |
|
Other anticoagulants |
|||
| Warfarin sodium | $28 for 30, 5 mg tablets | $4 for 30, 5 mg tablets of generic warfarin at Walmart | See latest prices |
| Pradaxa (dabigatran) | $472 for 60, 150 mg capsules | $39 for 60, 150 mg capsules of generic Pradaxa at CVS Pharmacy | See latest prices |
| Lovenox (enoxaparin) | $52 for 1, 10ml of 40 mg/0.4 mL syringe | $46 for 1, 10ml of 40 mg/0.4 mL syringe of generic Lovenox at CVS Pharmacy | See latest prices |
Eliquis costs by dose
The price of Eliquis is typically similar for the 2.5 mg and 5 mg tablet strengths, although costs may vary by pharmacy and quantity. Eliquis 2.5 mg may be prescribed for certain uses or for people with atrial fibrillation who meet specific criteria, such as older age, lower body weight, and reduced kidney function.
Compare Eliquis prices by strength |
|
|---|---|
|
(per 60 tablets) |
|
| Strength | SingleCare price for brand-name Eliquis |
| Eliquis 2.5 mg | $332 at Kroger |
| Eliquis 5 mg | $332 at Kroger |
Is Eliquis covered by insurance?
Eliquis is covered by many commercial insurance plans, Medicare Part D, and Medicaid plans. Even with coverage, you may be responsible for a copay or coinsurance amount. Coverage and out-of-pocket costs will vary by plan.
RELATED: How to get Eliquis cheaper on Medicare
How to get Eliquis without insurance
The cost of Eliquis without insurance can be high, but there are several ways to avoid paying the full retail price. Manufacturer assistance programs may help eligible patients, while SingleCare coupons and pharmacy price comparisons are available regardless of insurance status.
1. Use a SingleCare coupon
A SingleCare coupon may reduce the Eliquis 5 mg price without insurance from $378 to $156 for 28 tablets at Kroger. Visit SingleCare’s Eliquis coupon page to compare current prices at participating pharmacies near you. SingleCare is free to use, and registered members may qualify for additional savings.
2. Shop around
Eliquis prices may vary between pharmacies, even within the same area. Compare prices through SingleCare before filling your prescription to find the lowest available price at a participating pharmacy.
3. Ask the prescriber about alternative medications
Ask your healthcare provider about whether a lower-priced Eliquis alternative may be appropriate. Other direct factor Xa inhibitors, such as Xarelto (rivaroxaban), can also be expensive, but medications such as warfarin may cost less. Do not switch blood thinners without guidance from a healthcare provider.
4. Talk to county or city health officials
Local health departments and community health centers may be able to connect uninsured patients with prescription assistance programs, low-cost clinics, or health insurance enrollment support. Available programs and eligibility requirements vary by location.
RELATED: Eliquis savings guide
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The SingleCare prices in this article are the most accurate at the time of publishing in ZIP code 23666 as of Aug. 6, 2026. Prices vary by pharmacy. Visit our coupon page for updated drug prices at pharmacies near you.
- Eliquis apixaban tablet prescribing information, DailyMed (2025)
- Eliquis to face 98.6% global revenue collapse by 2031 as patent cliff strikes, The Pharma Letter (2026)
- Eliquis highlights of prescribing information, U.S. Food and Drug Administration (2026)
- Medically accurate: SingleCare’s Medical Review Board analyzes all of our content to confirm it’s in line with current medical advice.
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