What is Asclera: Uses, Warnings & Interactions

What is Asclera: Uses, Warnings & Interactions

Updated May 14, 2025 • Published Mar 30, 2024

Check our best Asclera prices

Asclera overview

BRAND NAMES:

Asclera, Varithena

Generic Names:

Asclera

Uses:

Treats varicose veins of the legs.

Therapeutic Classes:

Sclerosing Agent

Forms:

Injectable

How it’s taken:

By injection

What is Asclera used for?

What form(s) does Asclera come in

Injectable

What are common Asclera doses?

Ampule 2ml of 0.5%

Common Asclera prescriptions

Asclera
2ml of 0.5% ampule
Asclera
2ml of 1% ampule

How to take Asclera

Injection routeYour doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein.
Injection routeA nurse or other health provider will give you this medicine.
Wear compression stockings or a support hose on the treated leg all the time. The length of time depends on what kind of veins you had treated, but it is usually between 2 and 14 days. Continue to wear these during the day for 2 to 3 weeks longer. This will help prevent blood clots.
Walk for 10 to 20 minutes for Varithena„¢ or 15 to 20 minutes for Asclera® right away after the treatment and daily for at least the next several days. You may need to walk daily for up to a month.
Avoid heavy exercise, sunbathing, long plane flights, and hot baths or saunas for up to 1 week after you receive this medicine. Do not spend long periods of time being inactive (including long car rides) for 1 month after treatment.

What to do if you miss a dose of Asclera

Asclera contraindications

This medicine is not right for everyone. You should not receive it if you had an allergic reaction to polidocanol.

Asclera warnings

Tell your doctor if you are pregnant or breastfeeding, or if you have blood vessel, circulation, or blood clotting problems (including deep vein thrombosis, pulmonary embolism). Tell your doctor if you had a major surgery in the past 3 months.
This medicine may cause the following problems:Damage to the skin and other tissues at the injection site (may leave a scar)Increased risk of blood clots in the brain, heart, blood vessels, or lungs, which may lead to stroke, heart attack, deep vein thrombosis, or pulmonary embolism
Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.
Pain in your lower leg (calf)
Pain, itching, burning, swelling, or a lump under your skin where the needle is placed

Asclera interactions

Tell your doctor if you are pregnant or breastfeeding, or if you have blood vessel, circulation, or blood clotting problems (such as deep vein thrombosis, pulmonary embolism). Tell your doctor if you had a major surgery in the past 3 months.
This medicine may cause the following problems:Damage to the skin and other tissue at the injection site (may leave a scar)Blood clots

Asclera side effects

Serious Side Effects

Numbness or weakness in your arm or leg, or on one side of your body, sudden or severe headache, problems with vision, speech, or walking
Pain in your lower leg (calf)
Chest pain, trouble breathing, coughing up blood
Pain, itching, burning, swelling, or a lump under your skin where the needle is placed
Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

Less Serious Side Effects

Mild bruise where the needle is placed