Methotrexate Coupons & Prices

24 tablet, 2.5mg

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Methotrexate is an antimetabolite used to treat severe rheumatoid arthritis and psoriasis; and certain types of cancer. Methotrexate is a generic drug. The average Methotrexate price is about $77 for a supply of 24, 2.5 mg oral tablets. You can use our SingleCare savings offer to get a Methotrexate discount of up to 80% off of the retail price at participating pharmacies near you.

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Use your SingleCare CVS card or get a coupon for this price.
$5 off only applies on first prescription filled.

Use your SingleCare Walmart card or get a coupon for this price.
$5 off only applies on first prescription filled.

Free savings up to 80%* off the cost of your prescriptions

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How to get the most from your Methotrexate coupon

What is Methotrexate and what does it do?

Methotrexate is a tablet used to treat the symptoms of psoriasis and certain types of cancer including breast and lung cancer. This medication is also used together with rest and physical therapy to relieve symptoms associated with rheumatoid arthritis. Methotrexate works by slowing the growth of specific cells in the body.

Which drugs are similar to Methotrexate?

In addition to Methotrexate, several other similar brand-name drugs may be used to treat these symptoms including Rheumatrex Dose Pack and Trexall. Consult with your doctor to determine the best treatment for your condition.

What is the price of Methotrexate without insurance?

The average Methotrexate cost depends on several things: insurance coverage, dosage, and the pharmacy where you shop. The average Methotrexate cash price for a supply of 24, 2.5 mg oral tablets is about $77.

Is there a generic version of Methotrexate?

Methotrexate is a generic drug. Similar brand-name drugs include Rheumatrex Dose Pack and Trexall. Our free coupon may be used for savings on Methotrexate and alternative brand-name drugs for savings of up to 80%.

What dosages are available for Methotrexate?

Methotrexate oral tablets are only available in 2.5 mg strength. This medication is also as an injectable solution and injectable powder for injection. Follow your doctor's instructions for dosage and use of this medication.

How else can I save on Methotrexate?

There are several ways to save on Methotrexate. There is not a Methotrexate manufacturer coupon available at this time, but HealthWell Foundation Copay Program is a Patient Assistance Program that assists eligible patients with access to medications such as Methotrexate for free or at a savings. You can also use our free coupon. Our customers typically find that they save more by using our SingleCare savings card.

I am a pharmacy technician and I use this app all the time. It is awesome. I'm always trying to help others when they come in with no insurance and are trying to decide whether to get the antibiotics or inhaler.

Robert W.

My husband was between jobs and we had no insurance. Walmart employees told us about SingleCare and it saved us 220.00. I am not kidding! We were floored and so happy. I tell everyone about SingleCare.

Kimberly F.

Compared to GoodRx, SingleCare is a lot cheaper. My husband and I lost our insurance after 33 years of coverage. Thank you!

Sarah P.



Consumer Forms Tablet

Consumer Routes By mouth

Therapeutic Classes Antineoplastic Agent, Antipsoriatic, Antirheumatic, Cytotoxic

Methotrexate is a medication used to treat certain types of cancers and autoimmune diseases. Methotrexate belongs to a class of medications called antifolate drugs. Methotrexate is a generic drug also sold under the trade names Trexall and Rasuvo. Methotrexate has been in use since the 1950s. In the treatment of cancers and autoimmune disease, methotrexate use is very common.

  • Treats several kinds of cancer, including cancer of the blood, bone, lung, breast, head, or neck. Also treats rheumatoid arthritis and psoriasis (a skin disease).
  • You should not use this medicine if you have had an allergic reaction to methotrexate or if you are breastfeeding. You should not use this medicine for arthritis or psoriasis if you are pregnant, or if you have liver disease or certain problems with your blood or immune system. Make sure your doctor knows if you drink alcohol of any kind on a regular basis.
  • Oral routeMedicines used to treat cancer are very strong and can have many side effects. Before receiving this medicine, make sure you understand all the risks and benefits. It is important for you to work closely with your doctor during your treatment.
  • Your doctor will tell you how much medicine to use. Do not use more than directed. The correct schedule for this medicine is different for arthritis, psoriasis, and different kinds of cancer. For example, people who have arthritis or psoriasis often take this medicine only once a week.
  • Make sure you understand your personal dosing schedule. Ask your doctor and pharmacist if you are not sure when or how often to take your medicine.
  • If you take the medicine only once a week, it is best to take it on the same day each week.
  • Write down on a calendar or piece of paper when you are supposed to use your medicine. Keep the calendar or paper where you can see it. After you take your dose of medicine, cross off that date on your calendar or paper. This will help you remember if you took the medicine or if you still need to take it. If you need other ideas to help you keep track of your schedule, ask your pharmacist or other healthcare provider.
  • Using this medicine while you are pregnant can harm your unborn baby. The medicine may also cause birth defects if the father is using it when his sexual partner becomes pregnant. Use an effective form of birth control during treatment with methotrexate. For a man, continue birth control for at least 3 months after stopping treatment. For a woman, continue birth control until you have had two menstrual periods after stopping treatment. If a pregnancy occurs while you are using this medicine, tell your doctor right away.
  • Make sure your doctor knows if you have kidney disease, liver disease, a stomach ulcer, colitis, diabetes, hepatitis, HIV or AIDS, problems with your immune system, or any kind of problem with your blood (such as anemia). Tell your doctor if you get an infection of any kind.
  • This medicine may make your skin more sensitive to sunlight. Wear sunscreen. Do not use sunlamps or tanning beds. Tell your doctor if you have increased skin redness or other problems.
  • You may get infections more easily while you are using this medicine. Stay away from people with colds, flu, or other infections. Wash your hands often.
  • Your doctor will need to check your progress at regular visits while you are using this medicine. You may need to have blood tests or other kinds of medical tests. Be sure to keep all appointments.
  • Call your doctor right away if you think you have taken too much of this medicine.
  • Sores or white patches on your lips, mouth, or throat
  • Unusual bleeding, bruising, or weakness
Side effects
  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Nausea, vomiting, diarrhea, loss of appetite, stomach pain
  • Cough, fever, chest pain, trouble breathing, blue lips or fingers
  • Blistering, peeling, red skin rash
  • Fever
  • Unusual bleeding, bruising, or weakness
  • Eyes or skin turn yellow, or dark-colored urine or pale stools
  • Sores or white patches on your lips, mouth, or throat
  • Hair loss, headache, dizziness
  • There are many drugs that can interact with methotrexate. Some of these drugs are aspirin, phenytoin (Dilantin®), theophylline (Theo-Dur®), antibiotics (such as penicillin, tetracycline, Bactrim®, Septra®), and vitamin supplements that contain folic acid. Make sure your doctor knows about ALL other medicines you are using.
  • Make sure your doctor knows about any cancer treatments you are using, including cisplatin (Platinol®) or radiation.
  • If you have bone cancer, ask your doctor if you need to avoid using pain or arthritis medicine (such as aspirin, diclofenac, ibuprofen, indomethacin, Advil®, Aleve®, Bextra®, Celebrex®) or steroid medicines (such as prednisone).
  • If you have arthritis, make sure your doctor knows about all other medicines you are using to treat arthritis (such as aspirin, gold, ibuprofen, prednisone, sulfasalazine, Azulfidine®, Celebrex®, Plaquenil®).
  • Tell your doctor if you have used methotrexate before for any reason.
  • Talk to your doctor before getting flu shots or other vaccines while you are receiving methotrexate. Vaccines may not work as well while you are using this medicine.

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