Methotrexate Sodium Coupons & Prices

Methotrexate Sodium is a prescription generic medication used to treat certain types of cancers of the skin, breast, head, and neck. It is also used to treat certain forms of rheumatoid arthritis and severe psoriasis. The average retail price of Methotrexate Sodium is around $444.99. You can lower your cash price to $12.27 for 24, 2.5mg tablets by using a SingleCare Methotrexate Sodium discount card at CVS Pharmacy, Target, Longs Drugs, Walmart, Kroger and other local pharmacies.

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Methotrexate Sodium coupon at Walmart Neighborhood Market Pharmacy
$15.27
$ 12.27
$3 off with signupwith signup

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Methotrexate Sodium coupon at Walmart Pharmacy
$15.27
$ 12.27
$3 off with signupwith signup

Save an extra $3 on any eligible prescription! Sign up for free

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Methotrexate Sodium coupon at Kroger Pharmacy
$18.60
$ 15.60
$3 off with signupwith signup
Methotrexate Sodium coupon at Harris Teeter Pharmacy
$18.60
$ 15.60
$3 off with signupwith signup
Methotrexate Sodium coupon at Food Lion Pharmacy
$ 15.92
Methotrexate Sodium coupon at Publix Pharmacy
$ 16.62
$ 17.99
$25.39
$ 22.39
$3 off with signupwith signup
$33.18
$ 30.18
$3 off with signupwith signup

About SingleCare Pricing

SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.

Any SingleCare bonus savings, including the $3 signup bonus, may only be used once.

Prices updated: 12/05/2025

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About Methotrexate Sodium

Methotrexate Sodium is a prescription generic medication used to treat certain types of cancers of the skin, breast, head, and neck. It is also used to treat certain forms of rheumatoid arthritis and severe psoriasis. The average retail price of Methotrexate Sodium is around $444.99. You can lower your cash price to $12.27 for 24, 2.5mg tablets by using a SingleCare Methotrexate Sodium discount card at CVS Pharmacy, Target, Longs Drugs, Walmart, Kroger and other local pharmacies.

About Methotrexate Sodium

Methotrexate Sodium is a prescription generic medication used to treat certain types of cancers of the skin, breast, head, and neck. It is also used to treat certain forms of rheumatoid arthritis and severe psoriasis. The average retail price of Methotrexate Sodium is around $444.99. You can lower your cash price to $12.27 for 24, 2.5mg tablets by using a SingleCare Methotrexate Sodium discount card at CVS Pharmacy, Target, Longs Drugs, Walmart, Kroger and other local pharmacies.

Methotrexate Sodium FAQs

Medically reviewed by Kristi C. TorresPharm.D.
Licensed Pharmacist

How much does Methotrexate Sodium cost without insurance?

Methotrexate Sodium may cost around $444.99 or even more if you do not have insurance coverage. Using a SingleCare Methotrexate Sodium prescription discount card can help you to save on your prescription medication. Lower your cost to $12.27 for 24, 2.5mg tablets when you use your savings card at participating pharmacies.

How much does Methotrexate Sodium cost with insurance?

The average cost of Methotrexate Sodium with insurance tends to vary based on the type of health insurance plan you are enrolled in and the level of benefits you are entitled to. You may need to contact your insurance provider directly to get an accurate cost for your Methotrexate Sodium prescription. You can also save on Methotrexate Sodium by using SingleCare's Methotrexate Sodium coupons. Redeem instant savings and pay just $12.27 for 24, 2.5mg tablets of Methotrexate Sodium when you use your SingleCare coupon.

Does Medicare cover Methotrexate Sodium and how much does it cost?

Methotrexate Sodium is currently covered by all of the Medicare Part D and Medicare Advantage plans. The average Medicare copay for Methotrexate Sodium varies by plan and coverage stage. You can also save on this medication by using a SingleCare savings card. Redeem instant savings at participating pharmacies and pay a reduced rate of $12.27 for 24, 2.5mg tablets of Methotrexate Sodium prescriptions when you use your SingleCare discount card.

What is the brand name of Methotrexate Sodium?

Methotrexate Sodium is a generic prescription drug. The brand-name version of this medication is Rheumatrex.

What is Methotrexate Sodium?

Methotrexate Sodium is a prescription generic medication used to treat certain types of cancers of the skin, breast, head, and neck. It is also used to treat certain forms of rheumatoid arthritis and severe psoriasis. This medication works by interfering with the growth of certain cells in the body such as cancer cells and bone marrow cells. Methotrexate Sodium is usually used after all other medications have failed.

This medication comes in the form of oral tablets and an injectable solution. It is not meant to be taken every day. Check with your healthcare professional to learn more about the appropriate dose suited for you and the frequency in which you need to use this medication. Ensure you follow your doctor's instructions when taking this medication.

Methotrexate Sodium may lower your blood cell count and may be toxic to your organs. Your doctor may need to run blood tests often and may occasionally need to perform a liver biopsy while you are on this medication.

What are the side effects of Methotrexate Sodium?

Common side effects reported when using Methotrexate Sodium include nausea, headache, vomiting, diarrhea, shortness of breath, minor hair loss, hair thinning and rashes. Other serious side effects may include dark urine, easy bruising or bleeding, mouth ulcer, enlargement of glands and lymph nodes, skin discoloration.

Methotrexate Sodium decreases folate levels in the blood, and patients who take Methotrexate Sodium oftentimes must take a folic acid supplement.

Methotrexate Sodium should not be taken by pregnant women or women trying to have a baby as it can affect the development of the baby. Methotrexate Sodium has been noted to decrease sperm production in male patients. Consult your doctor if you are thinking of starting a family.

Allergic reactions to Methotrexate Sodium are rare but you should consult a doctor if you notice any symptoms of an allergic reaction includingI severe dizziness, trouble breathing, difficulty swallowing.

Other side effects not listed here may also occur as this is not a complete list. Consult your healthcare provider for medical advice on Methotrexate Sodium.

Medically reviewed by Kristi C. TorresPharm.D.
Licensed Pharmacist

Kristi C. Torres, Pharm.D., is a 2005 graduate of The University of Texas at Austin. Her professional background includes academic teaching roles, district-level management for a nationwide pharmacy chain, and clinic-based pharmacy management. Dr. Torres has a wide range of experience in pharmacy operations and has traveled to many states to open and convert clinic-based pharmacies for one of the largest healthcare systems in the nation.

Currently, she works for Tarrytown Expocare Pharmacy in Austin, Texas, serving the intellectual and developmental disability community. There, she leads the order entry team, overseeing orders from across the country.

Dr. Torres began working in pharmacy at the age of 16 in a small East Texas town. She currently resides in Round Rock, Texas, with her daughter and a Shih-Tzu puppy.

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Where are Methotrexate Sodium coupons from SingleCare accepted?

SingleCare is accepted at most national pharmacies and grocers, including the following:

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