What is Betamethasone Dipropionate: Uses, Warnings & Interactions

Follow the prescriber’s instructions. Do not use more than directed.

This medicine is for use only on the skin. Do not get any of it in your eyes, nose, mouth, or vagina. 

Avoid using this medicine on the face, groin, underarms, or on thin areas of the skin. Do not use it on skin areas that may rub or touch together.

Wash your hands with soap and water before and after you use this medicine.

Do not bandage, cover, or wrap the treated skin.

Applying betamethasone cream, gel, or ointment: 

• Apply a thin layer of the medicine to the affected area. Rub it in gently.

Applying betamethasone lotion: 

• Apply a few drops to the affected area and massage them gently into the skin.

Applying betamethasone spray: 

• Apply a thin layer of the medicine to the affected area. Rub it in gently.

Store betamethasone at room temperature.

Throw away any unused betamethasone spray after four weeks.

Apply a dose as soon as you can. If it is almost time for your next dose, wait until then and apply a regular dose. Do not apply extra medicine to make up for a missed dose.

This medicine is not right for everyone. 

Do not use it if you have had an allergic reaction to betamethasone or other corticosteroids.

Betamethasone dipropionate should only be used for four weeks. Call the prescriber if symptoms do not improve.

Do not use betamethasone (augmented) for longer than two weeks unless instructed.

• Do not use more than 50 grams of betamethasone (augmented) in a week.

• If symptoms do not improve after two weeks, talk to the prescriber.

Follow-up visits and blood tests may be necessary. Keep all appointments with the healthcare team and the prescriber.

Before starting prescription betamethasone, tell the prescriber if you are pregnant, breastfeeding, or have:

• Any history of reactions to topical corticosteroids

• Thinning of the skin at the application site

• Diabetes 

• Liver problems

• Adrenal gland problems

• Cataracts

• Glaucoma

Betamethasone can cause serious side effects, including:

• Adrenal gland problems

• Cushing’s syndrome (physical changes due to corticosteroid exposure)

• Cataracts or glaucoma

• High blood sugar

• Skin thinning or discoloration

• Growth inhibition in children

Pregnant or breastfeeding women should apply betamethasone to the smallest area of skin possible.

Tell any doctor or other healthcare provider who treats you that you are using this medicine.

Before starting betamethasone, tell the prescriber about all the drugs and supplements regularly taken, particularly other corticosteroids.

Tell other healthcare professionals about betamethasone treatment before they prescribe new medications.