Betamethasone dipropionate is a prescription topical corticosteroid that relieves skin swelling and itching. Doctors use it for any skin condition that can be treated with corticosteroids. It comes in a variety of dosage forms, but some products are “augmented.” These augmented products are absorbed more quickly through the skin. Though the dosage strength is the same, it’s a more potent form than betamethasone and can only be used for a short time.
Check our best Betamethasone Dipropionate prices
Diprolene, Sernivo
Betamethasone dipropionate, betamethasone dipropionate (augmented)
Treats skin pain, swelling, and itching due to inflammatory skin conditions. Betamethasone spray treats plaque psoriasis.
Topical corticosteroid
Cream, gel, lotion, ointment, spray
On the skin
Betamethasone dipropionate relieves itching, swelling, and discomfort due to various inflammatory skin conditions.
Cream, lotion, ointment, spray
0.05%
Augmented cream, gel, lotion, ointment
0.05%
For swelling, itching, and discomfort due to corticosteroid-responsive inflammatory skin conditions in adults and children 13 years of age and older:
Cream, gel, or ointment: Apply a thin layer once or twice daily to the affected skin
Lotion: Apply a few drops to the affected skin twice daily
Augmented lotion: Apply a few drops to the affected skin once or twice daily
For plaque psoriasis in adults:
Spray: Apply to the affected skin twice daily
Betamethasone Dipropionate
60ml of 0.05% bottle
Betamethasone Dipropionate
15gm of 0.05% tube
Betamethasone Dipropionate
45gm of 0.05% tube
Betamethasone Dipropionate
15gm of 0.05% tube of cream
Betamethasone Dipropionate
45gm of 0.05% tube of cream
Betamethasone Dipropionate
15gm of 0.05% tube of ointment
Betamethasone Dipropionate
45gm of 0.05% tube of ointment
Follow the prescriber’s instructions. Do not use more than directed.
This medicine is for use only on the skin. Do not get any of it in your eyes, nose, mouth, or vagina.
Avoid using this medicine on the face, groin, underarms, or on thin areas of the skin. Do not use it on skin areas that may rub or touch together.
Wash your hands with soap and water before and after you use this medicine.
Do not bandage, cover, or wrap the treated skin.
Applying betamethasone cream, gel, or ointment:
Apply a thin layer of the medicine to the affected area. Rub it in gently.
Applying betamethasone lotion:
Apply a few drops to the affected area and massage them gently into the skin.
Applying betamethasone spray:
Apply a thin layer of the medicine to the affected area. Rub it in gently.
Store betamethasone at room temperature.
Throw away any unused betamethasone spray after four weeks.
Apply a dose as soon as you can. If it is almost time for your next dose, wait until then and apply a regular dose. Do not apply extra medicine to make up for a missed dose.
This medicine is not right for everyone.
Do not use it if you have had an allergic reaction to betamethasone or other corticosteroids.
Betamethasone dipropionate should only be used for four weeks. Call the prescriber if symptoms do not improve.
Do not use betamethasone (augmented) for longer than two weeks unless instructed.
Do not use more than 50 grams of betamethasone (augmented) in a week.
If symptoms do not improve after two weeks, talk to the prescriber.
Follow-up visits and blood tests may be necessary. Keep all appointments with the healthcare team and the prescriber.
Before starting prescription betamethasone, tell the prescriber if you are pregnant, breastfeeding, or have:
Any history of reactions to topical corticosteroids
Thinning of the skin at the application site
Diabetes
Liver problems
Adrenal gland problems
Cataracts
Glaucoma
Betamethasone can cause serious side effects, including:
Adrenal gland problems
Cushing’s syndrome (physical changes due to corticosteroid exposure)
Cataracts or glaucoma
High blood sugar
Skin thinning or discoloration
Growth inhibition in children
Pregnant or breastfeeding women should apply betamethasone to the smallest area of skin possible.
Tell any doctor or other healthcare provider who treats you that you are using this medicine.
Before starting betamethasone, tell the prescriber about all the drugs and supplements regularly taken, particularly other corticosteroids.
Tell other healthcare professionals about betamethasone treatment before they prescribe new medications.
Talk to a doctor if you notice any signs or symptoms of a possible serious side effect, including:
Blurred vision, cloudy vision, vision changes, eye pain, sensitivity to light
Color changes on the skin, dark freckles, easy bruising, and muscle weakness
Severe itching, burning, or skin irritation
Redness, swelling, drainage, or pus on the skin
Weight gain around your neck, upper back, breast, face, or waist
Allergic reaction: Itching or hives, swelling in your face, mouth, tongue, or throat, trouble breathing
Skin redness
Swollen hair follicles
Itching
Blistering
Betamethasone dipropionate augmented cream prescribing information, DailyMed (NIH National Library of Medicine)
Betamethasone dipropionate augmented lotion prescribing information, DailyMed (NIH National Library of Medicine)
Betamethasone dipropionate augmented ointment prescribing information, DailyMed (NIH National Library of Medicine)
Betamethasone dipropionate cream prescribing information, DailyMed (NIH National Library of Medicine)
Betamethasone dipropionate gel prescribing information, DailyMed (NIH National Library of Medicine)
Betamethasone dipropionate lotion prescribing information, DailyMed (NIH National Library of Medicine)
Betamethasone dipropionate spray prescribing information, DailyMed (NIH National Library of Medicine)
Diprolene betamethasone dipropionate ointment prescribing information, DailyMed (NIH National Library of Medicine)
Sernivo betamethasone dipropionate spray prescribing information, DailyMed (NIH National Library of Medicine)
Health education, drug info, wellness & more
SingleCare is a prescription discount service that offers free coupons on thousands of prescription drugs. It can be used whether you have insurance, Medicare, Medicaid, or none of the above, but it cannot be combined with insurance.
SingleCare provides transparent drug pricing, so you can compare discounts at pharmacies near you. Browse singlecare.com to find drug discounts, helpful information about your prescription, and resources to help you make informed health decisions.
Prescription savings vary by prescription and by pharmacy, and may reach up to 80% off cash price. This is a medical discount plan. This is NOT insurance. This program offers you the opportunity to locate providers of various types of medical services who will offer their services to you at discounted rates. The range of discounts for medical or ancillary services provided under the plan will vary depending on the type of provider and service received. You are fully responsible for paying for all health care services but will be entitled to receive a discount from those health care providers in accordance with the specific pre-negotiated discounted fee schedule. This program does not guarantee the quality of the services or procedures offered by the providers. Except for prescription drugs which you will pay directly to the pharmacy at the time of purchase, all other services received through a program provider will be charged to the credit card on file in your member account. The charge will include an administrative fee for use of the program. Towers Administrators LLC is the licensed discount medical plan organization with its administrative office located at 4510 Cox Road, Suite 111, Glen Allen, VA 23060. SingleCare Services, LLC is the marketer of the discount medical plan organization including its website, singlecare.com, with its corporate office located at 99 High Street, Suite 2800, Boston, MA 02110. For additional information, including an up-to-date list of providers, or assistance with any issue related to program membership, please contact member support any time at www.singlecare.com, or by calling toll-free 844-234-3057, 24 hours, 7 days a week (except major holidays). Pharmacy names, logos, brands, and other trademarks are the property of their respective owners.
Blog articles are not medical advice. They are intended for general informational purposes and are not meant to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. If you think you may have a medical emergency, immediately call your physician or dial 911.
© 2026 SingleCare Administrators. All rights reserved
© 2026 SingleCare Administrators. All rights reserved