Biotrue is a sterile soft contact lens solution containing saline and hyaluronan as the lubricating agents. Hyaluronan greatly increases the ability of the eye to keep the lens moist over a long period compared to solutions using saline. Biotrue contains preservatives that also kill bacteria on the surface of the lens. On average, Biotrue costs $12.34 but you will pay $4.38 with a free SingleCare Biotrue coupon at stores near you, such as Target, Longs Drugs, Walgreens, and others. SingleCare discounts are available for over-the-counter products like Biotrue, when prescribed by a healthcare professional.
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SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.
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Prices updated: 12/20/2025
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Biotrue is a sterile soft contact lens solution containing saline and hyaluronan as the lubricating agents. Hyaluronan greatly increases the ability of the eye to keep the lens moist over a long period compared to solutions using saline. Biotrue contains preservatives that also kill bacteria on the surface of the lens. On average, Biotrue costs $12.34 but you will pay $4.38 with a free SingleCare Biotrue coupon at stores near you, such as Target, Longs Drugs, Walgreens, and others. SingleCare discounts are available for over-the-counter products like Biotrue, when prescribed by a healthcare professional.
Biotrue is a sterile soft contact lens solution containing saline and hyaluronan as the lubricating agents. Hyaluronan greatly increases the ability of the eye to keep the lens moist over a long period compared to solutions using saline. Biotrue contains preservatives that also kill bacteria on the surface of the lens. On average, Biotrue costs $12.34 but you will pay $4.38 with a free SingleCare Biotrue coupon at stores near you, such as Target, Longs Drugs, Walgreens, and others. SingleCare discounts are available for over-the-counter products like Biotrue, when prescribed by a healthcare professional.
The price of Biotrue averages $12.34, but prices will vary depending on where you buy. Biotrue costs $4.38 per 1, 360ml of bottle with a Biotrue coupon from SingleCare with a prescription.
Biotrue is usually not covered by insurance, but the retail price is only $12.34. If your doctor has prescribed Biotrue, with a SingleCare discount card, Biotrue costs $4.38.
Medicare Part D and Medicare Advantage prescription drug plans do not cover Biotrue. Consider instead using a SingleCare Biotrue coupon if you have a prescription for Biotrue. With SingleCare, the cost of Biotrue falls to $4.38.
Biotrue is an over-the-counter brand-name contact cleaning and storage solution from Bausch + Lomb. Contacts solution is available in a range of branded products, such as Opti-Free, and generic products, such as Up & Up and Equate. These products, however, do not include hyaluronan, a moistening agent that helps the lenses stay moist in the eye for a longer time.
Biotrue is a sterile soft contact lens cleaning and storage solution that contains saline and hyaluronan as the lubricating agents. Hyaluronan, which is a gel-like substance secreted by the eye, greatly increases the ability of the eye to keep the lens moist over a long period when it is absorbed into the lens.
Biotrue is marketed as a solution that preserves intact antibodies (proteins) on the surface of the lens while removing denatured proteins from the lens. Biotrue also helps to remove particles on the surface of the lens that may irritate. The disinfecting agents in Biotrue are polyquaternium and polyaminopropyl biguanide, preservatives that are commonly found in contact lens cleaning solutions, storage solutions, and rewetting drops.
Put three drops of Biotrue on each side of the contact lens and rub the lens between your fingers for 20 seconds. Flush the lens with the solution and place it in a container with fresh solution. Replace Biotrue 90 days after it has been opened to prevent possible infection.
Most people who use Biotrue experience no or minimal side effects. Common side effects of Biotrue are usually minor and temporary and involve site reactions on the surface of the eye. They include burning, stinging, irritation, blurred vision, redness, dry eye, and watering of the eye for a short period after the contact lenses are put in the eye. If these symptoms continue, remove the contact lenses from your eyes.
Allergic reactions to the preservatives are rare but can be swelling, redness, eye pain, and anaphylaxis, a sudden and dangerous drop in blood pressure. Again, remove the lenses at any sign of an allergic reaction to Biotrue.
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