What is Cefdinir: Uses, Warnings & Interactions

Updated May 14, 2025  •  Published Dec 30, 2020

Cefdinir is a generic prescription antibiotic commonly used to treat some types of bacterial infections. As a third-generation cephalosporin, cefdinir kills bacteria by blocking their ability to produce substances vital to their growth and function. Cefdinir is only taken by mouth as either a capsule or oral suspension. Doses are taken once or twice a day for a few days to clear up an infection.

Cefdinir overview

BRAND NAMES:

  • Brand-name cefdinir has been discontinued

Generic Names:

  • Cefdinir

Uses:

  • Treats bacterial infections of the lungs, sinuses, throat, skin, and ears

Therapeutic Classes:

  • Antibiotic, cephalosporin antibiotic, third generation cephalosporin antibiotic

Forms:

  • Capsule, oral suspension

How it’s taken:

  • By mouth

What is Cefdinir used for?

  • Healthcare professionals use cefdinir to treat bacterial infections of the lungs, sinuses, throat, skin, and ears.

What form(s) does Cefdinir come in

  • Capsule

    • 300 mg

  • Oral suspension (liquid)

    • 125 mg/5 mL

    • 250 mg/5 mL

What are common Cefdinir doses?

  • For community-acquired pneumonia:

    • In adults and adolescents: 300 mg taken every 12 hours for 10 days

    • In children 4 months to 12 years old: 14 mg/kg taken once daily or divided into two doses every 12 hours for 10 days

  • For chronic bronchitis in adults and adolescents: 600 mg daily taken once or divided into two doses taken every 12 hours for five to 10 days 

  • For sinusitis:

    • In adults and adolescents: 600 mg daily taken once or in two divided doses every 12 hours for five to 10 days 

    • In children 6 months to 12 years old: 14 mg/kg taken once daily or divided into two doses taken every 12 for 10 days

  • For bacterial infections of the throat or tonsils:

    • In adults: 600 mg daily taken once or in two divided doses every 12 hours for five to 10 days 

    • In children 6 months to 12 years old: 14 mg/kg taken once daily or divided into two doses taken every 12 hours for 5–10 days

  • For uncomplicated skin infections:

    • In adults: 300 mg taken every 12 hours for 10 days

    • In children, 6 months to 12 years old: 14 mg/kg taken once daily or divided into two doses taken every 12 hours for 10 days

  • For middle ear infections in children two months and older: 14 mg/kg taken once daily or divided into two doses taken every 12 hours for 5–10 days depending on age and severity of the infection

Common Cefdinir prescriptions

  • Cefdinir
    100ml of 125mg/5ml bottle

  • Cefdinir
    100ml of 250mg/5ml bottle

  • Cefdinir
    60ml of 125mg/5ml bottle

  • Cefdinir
    60ml of 250mg/5ml bottle

  • Cefdinir
    300mg capsule

  • Cefdinir
    10 capsules disp pack

How to take Cefdinir

  • Your healthcare provider will tell you how much medicine to use. Do not use more than directed.

  • Take or give all of the medicine in the prescription to clear up the infection, even if you or the child you’re caring for feels better after the first few doses.

  • How to take or administer cefdinir tablets:

    • Swallow the tablet whole with a drink of water.

    • Store cefdinir tablets at room temperature.

  • How to take or administer cefdinir oral suspension:

    • Cefdinir oral suspension comes as a powder in a bottle. A pharmacist will mix the powder with water to produce an oral suspension when you pick up the medicine.

    • The oral suspension is good for only ten days.

    • Shake the bottle well before measuring a dose.

    • Measure doses only with a calibrated oral syringe—the pharmacist will supply one. Do not use kitchen utensils.

    • Store cefdinir oral suspension at room temperature.

    • Discard the bottle and any remaining medicine 10 days after you pick it up at the drugstore.

What to do if you miss a dose of Cefdinir

  • Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. 

  • Do not take extra medicine to make up for a missed dose.

Cefdinir contraindications

  • This medicine is not right for everyone. 

  • Do not use this medicine if you have had an allergic reaction to cefdinir or to any type of cephalosporin antibiotic.

Cefdinir warnings

  • Tell any healthcare provider who treats you that you are using this medicine. Cefdinir can affect some important blood or urine tests.

  • Your healthcare provider may need follow-up visits to track your progress or monitor for side effects. Keep all appointments.

  • Tell your healthcare provider if you are pregnant before starting cefdinir.

  • Tell your healthcare provider if you have: 

  • This medicine can cause severe diarrhea that may occur several weeks or months after treatment ends. Call your healthcare provider if you experience severe diarrhea, watery diarrhea, persistent diarrhea, or bloody diarrhea. Do not take any medicine to treat the diarrhea until you have talked to your healthcare provider. 

  • Call your healthcare provider if your symptoms do not improve or if they get worse.

Cefdinir interactions

  • To avoid potentially hazardous drug interactions, tell the prescribing healthcare provider about all prescription drugs, over-the-counter medications, and supplements being taken.

  • Iron supplements and antacids can interfere with the body’s absorption of cefdinir, making the drug less effective at fighting off an infection. Take or administer the cefdinir dose at least two hours before or after an iron supplement or antacid is used.

  • Tell the healthcare provider if you are taking the gout medication probenecid. The combination may increase the risk of cefdinir side effects.

  • If you have diabetes and are monitoring urine glucose at home, cefdinir could alter your test results. Talk to a healthcare provider about urine glucose tests that are unaffected by cefdinir.

Cefdinir side effects

Serious side effects

Talk to a healthcare provider if you notice any signs or symptoms of a possible serious side effect, including:

  • Severe diarrhea, bloody diarrhea, stomach pain, cramps, bloating

  • Red or black stools, stomach pain

  • Pale skin, weakness, problems thinking, tiredness, mood changes, numbness and tingling in the hands and feet

  • Decrease in urination, swelling of the hands and feet, shortness of breath, tiredness, mental changes

  • Unusual bleeding or bruising

  • Sores or white patches on the lips, mouth, throat, or vagina

  • Blistering, peeling, or red skin rash

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

Less serious side effects

  • Diarrhea

  • Yeast infection

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