What is Coartem: Uses, Warnings & Interactions

Updated May 14, 2025  •  Published Dec 30, 2020

Coartem overview

BRAND NAMES:

  • Coartem

Generic Names:

  • Coartem

Uses:

  • Treats malaria.

Therapeutic Classes:

  • Antimalarial

Forms:

  • Tablet

How it’s taken:

  • By mouth

What is Coartem used for?

What form(s) does Coartem come in

  • Tablet

What are common Coartem doses?

  • Tablet 20-120MG

Common Coartem prescriptions

  • Coartem
    24 tablets bottle

  • Coartem
    20-120mg tablet

How to take Coartem

  • Your doctor will tell you how much medicine to use. Do not use more than directed.

  • Take this medicine with food, such as milk, pudding, or broth. Even if you do not feel hungry, try to eat because food helps your body absorb the medicine.

  • You may crush the tablet if you have trouble swallowing it. Mix the crushed tablet with 1 or 2 teaspoons of water in a clean container. After you swallow the mixture, rinse the container with a bit more water and swallow that also. Follow with milk, pudding, or broth.

  • Take all of the medicine in your prescription to clear up your infection, even if you feel better after the first few doses.

  • Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.

  • Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose. If you vomit within 2 hours of taking this medicine, take another dose. If you vomit the second dose, tell your doctor right away. You may need a different medicine to treat your condition.

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Store the medicine in the original package with the container tightly closed.

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

  • Take this medicine with food, such as milk, pudding, or broth. Even if you do not feel hungry, try to eat because food helps your body absorb the medicine.

  • Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.

  • You may crush the tablet if you have trouble swallowing it. Mix the crushed tablet with 1 or 2 teaspoons of water in a clean container. After you swallow the mixture, rinse the container with a bit more water and swallow that also. Follow with milk, pudding, or broth.

  • Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose. If you vomit within 2 hours of taking this medicine, take another dose. If you vomit the second dose, tell your doctor right away. You may need a different medicine to treat your condition.

  • Take all of the medicine in your prescription to clear up your infection, even if you feel better after the first few doses.

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Store the medicine in the original package with the container tightly closed.

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

  • Your doctor will tell you how much medicine to use. Do not use more than directed.

What to do if you miss a dose of Coartem

Coartem contraindications

  • This medicine is not right for everyone. Do not use it if you had an allergic reaction to artemether or lumefantrine.

Coartem warnings

  • Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, severe heart disease, slow heartbeat, a history of heart rhythm problems (including prolonged QT interval, congenital long QT interval), or low potassium or magnesium levels.

  • Birth control pills or patches may not work as well while you are using this medicine. Use a second form of birth control with your pills or patches.

  • Call your doctor if your symptoms do not improve or if they get worse.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

  • Lightheadedness or fainting

  • Unusual bleeding or bruising

  • Yellow skin or eyes

Coartem interactions

  • Do not use this medicine if you are also using carbamazepine, phenytoin, rifampin, or St John's wort.

  • Some medicines can affect how artemether/lumefantrine works. Tell your doctor if you are taking any of the following: AntibioticsBirth control pills or patchesDepression medicine (including amitriptyline, clomipramine, imipramine)HIV or AIDS medicine (including efavirenz, lopinavir, ritonavir)Medicine to treat a fungal infection (including fluconazole, itraconazole, ketoconazole)Medicine to treat heart rhythm problems (including amiodarone, disopyramide, flecainide, procainamide, quinidine, sotalol)Medicine to treat mental illness (including pimozide, ziprasidone)Other medicines to treat malaria infection (including halofantrine, mefloquine, or quinine)Seizure medicine

  • Do not eat grapefruit or drink grapefruit juice while you are using this medicine.

  • Do not eat grapefruit or drink grapefruit juice while you are using this medicine.

Coartem side effects

Serious Side Effects

  • Lightheadedness or fainting

  • Unusual bleeding or bruising

  • Yellow skin or eyes

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Chills, fever, headache, or muscle pains after you finish treatment

  • Dry mouth, increased thirst, muscle cramps, nausea, vomiting

  • Fast, pounding, or uneven heartbeat or pulse

Less Serious Side Effects

  • Loss of appetite

  • Headache, dizziness

  • Tiredness or weakness

  • Joint or muscle pain

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