Emsam Coupons & Prices

Emsam is a prescription antidepressant medication used to treat patients with major depressive disorder. Emsam is a monoamine oxidase inhibitor (MAOI) drug. There is currently no generic alternative of Emsam available. The average retail price of Emsam is around $2,663.13. SingleCare can help you to save with a reduced rate of $2,167.14 with a Emsam coupon. This coupon can be redeemed at participating pharmacies such as CVS Pharmacy, Target, Walgreens, Longs Drugs, Walmart Pharmacy, Kroger, and Fry's.

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Emsam coupon at Walgreens Pharmacy
$2170.14
$ 2,167
$3 off with signupwith signup

Show this free card to your pharmacist.

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Emsam coupon at Kroger Pharmacy
$2207.68
$ 2,205
$3 off with signupwith signup

Save an extra $3 on any eligible prescription! Sign up for free

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Emsam coupon at Harris Teeter Pharmacy
$2207.68
$ 2,205
$3 off with signupwith signup
Emsam coupon at CVS Pharmacy
$2306.18
$ 2,303
$3 off with signupwith signup
Emsam coupon at Food Lion Pharmacy
$ 2,305
Emsam coupon at Publix Pharmacy
$2359.33
$ 2,356
$3 off with signupwith signup
$2370.35
$ 2,367
$3 off with signupwith signup
$2370.35
$ 2,367
$3 off with signupwith signup
$2383.36
$ 2,380
$3 off with signupwith signup

About SingleCare Pricing

SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.

Any SingleCare bonus savings, including the $3 signup bonus, may only be used once.

Prices updated: 12/05/2025

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About Emsam

Emsam is a prescription antidepressant medication used to treat patients with major depressive disorder. Emsam is a monoamine oxidase inhibitor (MAOI) drug. There is currently no generic alternative of Emsam available. The average retail price of Emsam is around $2,663.13. SingleCare can help you to save with a reduced rate of $2,167.14 with a Emsam coupon. This coupon can be redeemed at participating pharmacies such as CVS Pharmacy, Target, Walgreens, Longs Drugs, Walmart Pharmacy, Kroger, and Fry's.

About Emsam

Emsam is a prescription antidepressant medication used to treat patients with major depressive disorder. Emsam is a monoamine oxidase inhibitor (MAOI) drug. There is currently no generic alternative of Emsam available. The average retail price of Emsam is around $2,663.13. SingleCare can help you to save with a reduced rate of $2,167.14 with a Emsam coupon. This coupon can be redeemed at participating pharmacies such as CVS Pharmacy, Target, Walgreens, Longs Drugs, Walmart Pharmacy, Kroger, and Fry's.

Emsam FAQs

Medically reviewed by Karen BergerPharm.D.
Licensed Pharmacist

How much does Emsam cost without insurance?

Without the necessary insurance coverage, you may end up paying a cash price as high as $2,663.13 for your Emsam prescription. To save on this cost, use a SingleCare Emsam coupon and pay $2,167.14 per 1, 30 patch 24 hour box for your Emsam refill. These savings are redeemable at thousands of pharmacies.

How much does Emsam cost with insurance?

The cost of Emsam with insurance may vary based on the type of insurance coverage plan that you are enrolled in. Contact your insurance provider directly to find out exactly how much Emsam costs under your current insurance plan. SingleCare can help you to easily save on your Emsam purchases. Pay our lowest price of $2,167.14 for your Emsam purchase when you use SingleCare’s Emsam copay card.

Does Medicare cover Emsam and how much does it cost?

Emsam is commonly covered by Medicare Part D and Medicare Advantage plans. Your copay for Emsam with Medicare varies. SingleCare can help you to save on your Emsam prescription total. Just use a SingleCare prescription savings card at any participating pharmacy to pay $2,167.14 for your prescription refills.

Is there a generic of Emsam?

Emsam is a brand-name prescription drug that contains the ingredient selegiline. There is currently no generic version of Emsam.

What is Emsam?

Emsam is an FDA-approved prescription antidepressant medication used to treat patients with major depressive disorder. The active ingredient in this medication is selegiline. It works by restoring the balance of natural substances in the brain which helps to improve your mood and feelings of well-being.

Emsam comes in the form of a transdermal patch that is meant for use on the skin only. It can be applied to the upper torso, upper thigh, or the outer surface of the upper arm. Follow your medication guide closely when using this medication. Clean and dry the area of skin that you intend to apply this patch. One patch should be applied daily (after removing the previous patch) and should be used in a different area of the body to avoid irritation. Do not wear more than one of these patches at a time.

Your doctor may start you off with a low dose and gradually increase it over time. This helps to reduce the risk of side effects. Once your condition begins to improve, your doctor will reassess your treatment and may work with you to reduce your dose. Follow your doctor's instructions closely when using these patches. Before using Emsam, tell your doctor about your medical conditions and history, and all of the medications you take, including prescription and OTC drugs, vitamins, and supplements. Avoid alcohol when using Emsam. Do not drive until you know how this medication affects you.

What are the side effects of Emsam?

Common side effects resulting from the use of Emsam may include application site reaction, headache, trouble sleeping, diarrhea, dry mouth, indigestion, rash, and weight changes. A common side effect is orthostatic hypotension, which is when blood pressure drops when standing up from a sitting or lying down position, causing dizziness. If this occurs, stand up slowly while holding on to something stable for support.

This drug, in some rare cases, may cause an attack of extremely high blood pressure. Many food (such as foods rich in tyramine) and drug interactions can increase the risk of this happening. Stop using this drug and seek emergency medical assistance if you experience sudden and severe headaches, fast heartbeats, confusion, sweating, vomiting, neck stiffness, or pounding in the neck or ears.

This is not a complete list of side effects. Consult your doctor or healthcare professional for additional information and medical advice regarding other possible side effects or drug interactions. You can report negative side effects to the FDA.

Medically reviewed by Karen BergerPharm.D.
Licensed Pharmacist

After receiving her doctorate from the University of Pittsburgh School of Pharmacy, Karen Berger, Pharm.D., has worked in both chain and independent community pharmacies. She currently works at an independent pharmacy in New Jersey. Dr. Berger enjoys helping patients understand medical conditions and medications—both in person as a pharmacist, and online as a medical writer and reviewer.

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Where are Emsam coupons from SingleCare accepted?

SingleCare is accepted at most national pharmacies and grocers, including the following:

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