What is Enbrel Mini: Uses, Warnings & Interactions

Updated May 14, 2025  •  Published Dec 30, 2020

Enbrel Mini overview

BRAND NAMES:

  • Enbrel, Enbrel Mini

Generic Names:

  • Enbrel Mini

Uses:

  • Treats rheumatoid arthritis, psoriatic arthritis, juvenile idiopathic arthritis, ankylosing spondylitis, and plaque psoriasis.

Therapeutic Classes:

  • Immune Suppressant, Immunological Agent

Forms:

  • Injectable

How it’s taken:

  • By injection

What is Enbrel Mini used for?

What form(s) does Enbrel Mini come in

  • Injectable

What are common Enbrel Mini doses?

  • Cartridge 1ML of 50MG/ML

Common Enbrel Mini prescriptions

  • Enbrel Mini
    0.98ml of 50mg/ml cartridge

  • Enbrel Mini
    1ml of 50mg/ml cartridge

How to take Enbrel Mini

  • Injection routeThrow away used needles in a hard, closed container that the needles cannot poke through. Keep this container away from children and pets.

  • Injection routeYour doctor will prescribe your exact dose and tell you how often it should be given. This medicine is given as a shot under your skin.

  • Injection routeA nurse or other health provider will give you this medicine.

  • Injection routeYou may be taught how to give your medicine at home. Make sure you understand all instructions before giving yourself an injection. Do not use more medicine or use it more often than your doctor tells you to.

  • Injection routeYou will be shown the body areas where this shot can be given. Use a different body area each time you give yourself a shot. Keep track of where you give each shot to make sure you rotate body areas.

  • Allow the medicine to come to room temperature for 15 to 30 minutes before you use it. Do not shake it.

  • Prefilled cartridge, syringe, or autoinjector: Do not remove the needle cap or cover from the cartridge, syringe, or autoinjector until you are ready to use it.If the amount of liquid in the prefilled syringe does not fall between the purple indicator lines, do not use that syringe.Push the door button on the AutoTouch„¢ reusable autoinjector and insert the Enbrel Mini„¢ prefilled cartridge. It should slide freely and completely into the door.

  • Vial: Mix the medicine with the liquid provided in your dose kit. Gently swirl the medicine to mix it.Write the date you mixed the medicine on the sticker from the dose kit. Attach the sticker to the vial.After your dose, put the unused mixture in the refrigerator right away. Do not mix vials together. Throw away any unused medicine after 14 days.

  • Injection routeUse a new needle and syringe each time you inject your medicine.

  • This medicine should come with a Medication Guide. Ask your pharmacist for a copy if you do not have one.

  • Missed dose: Injection routeCall your doctor or pharmacist for instructions.

  • Injection routeIf you store this medicine at home, keep it in the refrigerator. Do not freeze. You may also store this medicine at room temperature, away from heat, light, or humidity for up to 14 days. Do not return it to the refrigerator. The reconstituted solution should be used right away or may be refrigerated for up to 14 days. Throw away unused medicine after 14 days.

  • Do not refrigerate the AutoTouch„¢ reusable autoinjector. Keep it at room temperature.

  • Injection routeYou may be taught how to give your medicine at home. Make sure you understand all instructions before giving yourself an injection. Do not use more medicine or use it more often than your doctor tells you to.

  • Allow the medicine to come to room temperature for 15 to 30 minutes before you use it. Do not shake it.

  • Do not refrigerate the AutoTouch„¢ reusable autoinjector. Keep it at room temperature.

  • Injection routeA nurse or other health provider will give you this medicine.

  • This medicine should come with a Medication Guide. Ask your pharmacist for a copy if you do not have one.

  • Vial: Mix the medicine with the liquid provided in your dose kit. Gently swirl the medicine to mix it.Write the date you mixed the medicine on the sticker from the dose kit. Attach the sticker to the vial.After your dose, put the unused mixture in the refrigerator right away. Do not mix vials together. Throw away any unused medicine after 14 days.

  • Injection routeUse a new needle and syringe each time you inject your medicine.

  • Injection routeThrow away used needles in a hard, closed container that the needles cannot poke through. Keep this container away from children and pets.

  • Injection routeIf you store this medicine at home, keep it in the refrigerator. Do not freeze. You may also store this medicine at room temperature, away from heat, light, or humidity for up to 14 days. Do not return it to the refrigerator. The reconstituted solution should be used right away or may be refrigerated for up to 14 days. Throw away unused medicine after 14 days.

  • Injection routeYou will be shown the body areas where this shot can be given. Use a different body area each time you give yourself a shot. Keep track of where you give each shot to make sure you rotate body areas.

  • Injection routeYour doctor will prescribe your exact dose and tell you how often it should be given. This medicine is given as a shot under your skin.

  • Prefilled cartridge, syringe, or autoinjector: Do not remove the needle cap or cover from the cartridge, syringe, or autoinjector until you are ready to use it.If the amount of liquid in the prefilled syringe does not fall between the purple indicator lines, do not use that syringe.Push the door button on the AutoTouch„¢ reusable autoinjector and insert the Enbrel Mini„¢ prefilled cartridge. It should slide freely and completely into the door.

  • Missed dose: Injection routeCall your doctor or pharmacist for instructions.

What to do if you miss a dose of Enbrel Mini

Enbrel Mini contraindications

  • This medicine is not right for everyone. Do not use it if you had an allergic reaction to etanercept or if you have an infection in the blood (sepsis).

Enbrel Mini warnings

  • Tell your doctor if you are pregnant or breastfeeding, or if you have diabetes, heart failure, liver problems (including hepatitis), multiple sclerosis or any nervous system problem, granulomatosis with polyangiitis, or a history of cancer, seizures, or Guillain-Barré syndrome. Tell your doctor if you are allergic to latex.

  • This medicine may cause you to get infections more easily. Tell your doctor if you have any type of infection (including tuberculosis, hepatitis B) before you start treatment. Also tell your doctor if you or a family member has a history of tuberculosis (TB). Take precautions to avoid illness. Wash your hands often.

  • This medicine may cause the following problems: Increased risk of cancer, including lymphoma, leukemia, and skin cancerNervous system problemsAutoimmune problems, including lupus-like syndrome and autoimmune hepatitisHeart failure

  • You will need a skin test for TB before you start using this medicine. Tell your doctor if you or anyone in your home has ever had a positive reaction to a TB skin test.

  • This medicine may make you bleed, bruise, or get infections more easily. Take precautions to prevent illness and injury. Wash your hands often.

  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

  • Numbness, tingling, or burning pain in your hands, arms, legs, or feet

  • Seizures

  • Skin changes or growths; red, scaly patches on the skin

  • Sores or white patches on your lips, mouth, or throat

  • Swollen glands in your neck, armpits, or groin

  • Trouble breathing, cold sweat, blue skin, swelling in your hands, ankles, or feet

  • Unusual bleeding, bruising, tiredness, or weakness

Enbrel Mini interactions

  • Some medicines can affect how etanercept work. Tell your doctor if you are using any of the following: Abatacept, anakinra, cyclophosphamideSteroid medicine (including dexamethasone, hydrocortisone, methylprednisolone, prednisolone, prednisone)

  • This medicine may interfere with vaccines. Ask your doctor before you get a flu shot or any other vaccines.

  • This medicine may cause the following problems: Increased risk of cancer, including lymphoma, leukemia, and skin cancerNervous system problemsAutoimmune problems, including lupus-like syndrome and autoimmune hepatitisHeart failure

  • Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Enbrel Mini side effects

Serious Side Effects

  • Swollen glands in your neck, armpits, or groin

  • Dark urine or pale stools, nausea, vomiting, loss of appetite, stomach pain, yellow skin or eyes

  • Change in how much or how often you urinate, painful or difficult urination

  • Seizures

  • Blistering, peeling, red skin rash

  • Numbness, tingling, or burning pain in your hands, arms, legs, or feet

  • Chest pain, coughing up blood, muscle pain, night sweats, weight loss

  • Sores or white patches on your lips, mouth, or throat

  • Unusual bleeding, bruising, tiredness, or weakness

  • Change in vision, eye pain

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Fever, chills, cough, runny or stuffy nose, sore throat, body aches

  • Trouble breathing, cold sweat, blue skin, swelling in your hands, ankles, or feet

  • Skin changes or growths, red, scaly patches on the skin

Less Serious Side Effects

  • Pain, redness, swelling, itching, bleeding, or bruising where the shot was given

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