Estriol Coupons & Prices

Estriol is a weak estrogen, a female hormone, that is prescribed as hormone replacement therapy to menopausal women with a uterus to reduce physical changes caused by menopause. These changes include hot flashes, night sweats, vaginal dryness, and bone loss. Estriol is also available over-the-counter as Estriol vaginal cream. Estriol's price is $828.59 for 1.20, 25gm of bottles and is usually available only at compounding pharmacies. You may get a discounted price as low as $11,325.41 with a SingleCare Estriol coupon if the pharmacy you use dispenses Estriol.

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Estriol coupon at Kroger Pharmacy
$11328.41
$ 11,325
$3 off with signupwith signup

Show this free card to your pharmacist.

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Estriol coupon at Harris Teeter Pharmacy
$11328.41
$ 11,325
$3 off with signupwith signup

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Estriol coupon at Food Lion Pharmacy
$ 11,818
Estriol coupon at CVS Pharmacy
$11990.76
$ 11,988
$3 off with signupwith signup
Estriol coupon at Publix Pharmacy
$12095.57
$ 12,093
$3 off with signupwith signup
Estriol coupon at Walmart Neighborhood Market Pharmacy
$12162.55
$ 12,160
$3 off with signupwith signup
$12162.55
$ 12,160
$3 off with signupwith signup
$12267.99
$ 12,265
$3 off with signupwith signup
$ 12,790

About SingleCare Pricing

SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.

Any SingleCare bonus savings, including the $3 signup bonus, may only be used once.

Prices updated: 12/05/2025

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About Estriol

Estriol is a weak estrogen, a female hormone, that is prescribed as hormone replacement therapy to menopausal women with a uterus to reduce physical changes caused by menopause. These changes include hot flashes, night sweats, vaginal dryness, and bone loss. Estriol is also available over-the-counter as Estriol vaginal cream. Estriol's price is $828.59 for 1.20, 25gm of bottles and is usually available only at compounding pharmacies. You may get a discounted price as low as $11,325.41 with a SingleCare Estriol coupon if the pharmacy you use dispenses Estriol.

About Estriol

Estriol is a weak estrogen, a female hormone, that is prescribed as hormone replacement therapy to menopausal women with a uterus to reduce physical changes caused by menopause. These changes include hot flashes, night sweats, vaginal dryness, and bone loss. Estriol is also available over-the-counter as Estriol vaginal cream. Estriol's price is $828.59 for 1.20, 25gm of bottles and is usually available only at compounding pharmacies. You may get a discounted price as low as $11,325.41 with a SingleCare Estriol coupon if the pharmacy you use dispenses Estriol.

Estriol FAQs

How much does Estriol cost without insurance?

Uninsured customers pay an average of $828.59 and Estriol is mainly purchased from compounding pharmacies. However, you may be able to purchase Estriol at your pharmacy. If so, you could pay only $11,325.41 with a SingleCare Estriol coupon. On your other prescriptions, a SingleCare discount card can reduce prices up to 80%.

How much does Estriol cost with insurance?

Estriol copay costs may vary depending on your insurance plan. With SingleCare, Estriol costs $11,325.41, which may be lower than your copay. So, while you will probably purchase Estriol from a compounding pharmacy, you might be able to fill your prescription at your favorite pharmacy. So ask your pharmacist if you can fill your Estriol prescription and then ask to compare your insurance Estriol price with the SingleCare discount card.

Does Medicare cover Estriol and how much does it cost?

Estriol is not covered by Medicare prescription drug plans. Patients without Medicare can rely on their SingleCare Estriol coupon if their pharmacy will fill their Estriol prescription. SingleCare reduces the price of Estriol to $11,325.41. Our free and reusable coupons for all prescription drugs are accepted at many participating pharmacies located near you, like Target, Walmart, and Duane Reade.

What is the brand name of Estriol?

In the United States, Estriol is a generic prescription drug available from compounding pharmacies only. There are no brand-name versions in the U.S.

Over-the-counter Estriol cream is available under several brand names, such as Emerita and Life-Flo Estriol-Care, both from NutraMarks. Estriol cream is widely available in Europe as a prescription cream in both brand-name and generic formulas.

What is Estriol?

Estriol is a female hormone, estrogen, that is prescribed as hormone replacement therapy to menopausal women with a uterus to reduce physical changes caused by menopause. These changes include hot flashes, night sweats, vaginal dryness, and bone loss. Estriol is a weak estrogen compared to estradiol and estrone, the other two estrogens produced by the body. Because of this, Estriol is used as a “gentler” hormone replacement therapy that has fewer and less severe side effects.

Although widely available in Europe, Estriol is rarely prescribed in the United States because other, more effective drugs are available. In particular, Estriol has not been shown to consistently help with improving osteoporosis.

Estriol is administered as a capsule, lozenge, cream, gel, or vaginal suppository. Estriol is available in the United States as non-prescription Estriol cream to specifically treat vaginal dryness, itching, and irritation due to menopause. Estriol cream is applied directly to the vaginal tissues.

What are the side effects of Estriol?

Common side effects of Estriol include but are not limited to breast tenderness, vaginal discomfort, nausea, vomiting, stomach cramps, headache, migraine, bloating, weight changes, and thinning hair. Allergic reactions are uncommon, but they include rashes or hives. Mood changes are rare but include anxiety, nervousness, irritability, and depression.

Where are Estriol coupons from SingleCare accepted?

SingleCare is accepted at most national pharmacies and grocers, including the following:

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