What is Gel-One: Uses, Warnings & Interactions

Updated May 14, 2025  •  Published Dec 30, 2020

Gel-One overview

BRAND NAMES:

  • Visco-3, Visco-3, TriVisc, TriLURON, Orthovisc, Supartz FX, Durolane, Euflexxa, Gel-One, GelSyn-3, GenVisc 850, Hyalgan, Hymovis, Monovisc

Generic Names:

  • Gel-One

Uses:

  • Treats severe pain in your knee due to osteoarthritis.

Therapeutic Classes:

  • Musculoskeletal Agent, Antirheumatic, Cartilaginous Defect Repair Agent

Forms:

  • Injectable

How it’s taken:

  • By injection

What is Gel-One used for?

What form(s) does Gel-One come in

  • Injectable

What are common Gel-One doses?

  • Syringe 3ML of 30MG/3ML

Common Gel-One prescriptions

  • Gel-One
    3ml of 30mg/3ml syringe

How to take Gel-One

  • Your doctor will tell you how many injections you will need. This medicine is injected into your knee joint.

  • Injection routeA nurse or other health provider will give you this medicine.

  • Your doctor will tell you how many injections you will need. This medicine is injected into your knee joint.

  • Injection routeA nurse or other health provider will give you this medicine.

What to do if you miss a dose of Gel-One

Gel-One contraindications

  • This medicine is not right for everyone. You should not receive it if you had an allergic reaction to hyaluronic acid or if you have a bleeding disorder.

Gel-One warnings

  • Tell your doctor if you are pregnant or breastfeeding, or if you have any allergies, including to birds, feathers, or eggs.

  • Rest your knee for 48 hours after you receive an injection. Do not do strenuous, weightbearing activities, such as jogging or tennis. Avoid activities that keep you standing for longer than 1 hour.

Gel-One interactions

  • Tell your doctor if you are pregnant or breastfeeding, or if you have any allergies, including to birds, feathers, or eggs.

  • Rest your knee for 48 hours after you receive an injection. Do not do strenuous, weightbearing activities, such as jogging or tennis. Avoid activities that keep you standing for longer than 1 hour.

Gel-One side effects

Serious Side Effects

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Pain, redness, or swelling where the medicine is injected

Less Serious Side Effects

  • Pain, redness, or swelling where the medicine is injected

  • Mild increase in pain or swelling in your knee

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