What is Granix: Uses, Warnings & Interactions

Updated May 14, 2025  •  Published Jan 25, 2023

Granix overview

BRAND NAMES:

  • Granix

Generic Names:

  • Granix

Uses:

  • Helps your body make white blood cells after you receive cancer medicine.

Therapeutic Classes:

  • Hematopoietic

Forms:

  • Injectable

How it’s taken:

  • By injection

What is Granix used for?

Granix is used to treat neutropenia, a lack of certain white blood cells caused by receiving chemotherapy with certain cancer medications. It works by stimulating your bone marrow to make more white blood cells.

What form(s) does Granix come in

  • Injectable

What are common Granix doses?

  • Syringe 0.5ml of 300mcg/0.5ml

  • Syringe 0.8ml of 480mcg/0.8ml

  • Vial 1ml of 300mcg/ml

  • Vial 1.6ml of 480mcg/1.6ml

Common Granix prescriptions

  • Granix
    0.5ml of 300mcg/0.5ml syringe

  • Granix
    0.8ml of 480mcg/0.8ml syringe

  • Granix
    1.6ml of 480mcg/1.6ml vial

  • Granix
    1ml of 300mcg/ml vial

How to take Granix

  • Injection routeYour doctor will prescribe your exact dose and tell you how often it should be given. This medicine is given as a shot under your skin.

  • Injection routeA nurse or other health provider will give you this medicine.

  • Injection routeYou may be taught how to give your medicine at home. Make sure you understand all instructions before giving yourself an injection. Do not use more medicine or use it more often than your doctor tells you to.

  • Start using the medicine 24 hours or more after you finish your chemotherapy. However, do not use it within 24 hours before you begin another chemotherapy.

  • Do not shake the syringe. Do not use the medicine if it is cloudy, discolored, or has particles in it.

  • If the medicine has been in the refrigerator, let it warm to room temperature for 30 minutes before you use it.

  • Injection routeYou will be shown the body areas where this shot can be given. Use a different body area each time you give yourself a shot. Keep track of where you give each shot to make sure you rotate body areas.

  • Each syringe should be used only once. Throw the syringe away after your dose. Do not save leftover medicine.

  • Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.

  • Missed dose: Call your doctor, treatment clinic, or home health caregiver for instructions if you miss a dose.

  • Injection routeIf you store this medicine at home, keep it in the refrigerator. Do not freeze. Leave the medicine in the carton until you are ready to use it. You can leave the medicine out of the refrigerator for up to 5 days. If you do not use it in 5 days, put it back in the refrigerator. Any unused medicine left out of the refrigerator for more than 5 days should be thrown away.

  • Injection routeThrow away used needles in a hard, closed container that the needles cannot poke through. Keep this container away from children and pets.

What to do if you miss a dose of Granix

Granix contraindications

  • This medicine is not right for everyone. You should not receive it if you had an allergic reaction to filgrastim or pegfilgrastim.

Granix warnings

  • Tell your doctor if you are pregnant or breastfeeding, or if you have sickle cell disease.

  • This medicine may cause the following problems:Damage to the spleen, including possible ruptureAcute respiratory distress syndrome (ARDS)Kidney damageCapillary leak syndrome (blood vessel problem)

  • Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results.

  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Granix interactions

  • Some medicines can affect how tbo-filgrastim works. Tell your doctor if you are using lithium.

  • This medicine may cause the following problems:Damage to the spleen, including possible ruptureAcute respiratory distress syndrome (ARDS)Capillary leak syndrome (blood vessel problem)

  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Granix side effects

Serious Side Effects

  • Swelling of your hands, ankles, feet, or lower legs

  • Decrease in how much or how often you urinate, red or dark brown urine, cloudy urine, lower back or side pain

  • Pain on the left upper side your stomach or left shoulder

  • Lightheadedness, dizziness, fainting

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Chest pain or tightness, trouble breathing

Less Serious Side Effects

  • Bone pain

  • Pain, redness, itching, burning, or swelling where the shot was given