Hydroxyurea is an FDA approved generic prescription drug that is used to treat chronic myeloid leukemia, squamous cell cancer of the head and neck, a skin cancer called melanoma, and sickle cell anemia. Hydroxyurea blocks the ability of cancer cells to produce or use DNA, so they eventually die off without producing new cancer cells. Cancer and chemotherapy can be complicated subjects, so our FAQs section has more information about Hydroxyurea, how it works, possible side effects, how much Hydroxyurea costs, and how you can save money on your Hydroxyurea prescription. Hydroxyurea can cost an average cash price of $87.93 at full price. A SingleCare Hydroxyurea coupon could reduce that total cost to $17.89 for 60, 500mg capsules.
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SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.
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Prices updated: 12/05/2025
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Hydroxyurea is an FDA approved generic prescription drug that is used to treat chronic myeloid leukemia, squamous cell cancer of the head and neck, a skin cancer called melanoma, and sickle cell anemia. Hydroxyurea blocks the ability of cancer cells to produce or use DNA, so they eventually die off without producing new cancer cells. Cancer and chemotherapy can be complicated subjects, so our FAQs section has more information about Hydroxyurea, how it works, possible side effects, how much Hydroxyurea costs, and how you can save money on your Hydroxyurea prescription. Hydroxyurea can cost an average cash price of $87.93 at full price. A SingleCare Hydroxyurea coupon could reduce that total cost to $17.89 for 60, 500mg capsules.
Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.
| Pharmacy | Hydroxyurea Retail Price | Hydroxyurea SingleCare Price |
|---|---|---|
| CVS Pharmacy | $79.80 | $79.65 |
| Walmart | $23.28 | $23.28 |
| Walgreens | $18.60 | $12.00 |
| Kroger Pharmacy | $60.00 | $21.00 |
| Albertsons Pharmacy | $81.00 | $27.60 |
These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.
Hydroxyurea is an FDA approved generic prescription drug that is used to treat chronic myeloid leukemia, squamous cell cancer of the head and neck, a skin cancer called melanoma, and sickle cell anemia. Hydroxyurea blocks the ability of cancer cells to produce or use DNA, so they eventually die off without producing new cancer cells. Cancer and chemotherapy can be complicated subjects, so our FAQs section has more information about Hydroxyurea, how it works, possible side effects, how much Hydroxyurea costs, and how you can save money on your Hydroxyurea prescription. Hydroxyurea can cost an average cash price of $87.93 at full price. A SingleCare Hydroxyurea coupon could reduce that total cost to $17.89 for 60, 500mg capsules.
The pharmacy cost of Hydroxyurea can be around $87.93. That same prescription could cost $17.89 for 60, 500mg capsules with a SingleCare savings card, which you can use at major pharmacies throughout the country.
The copay cost of Hydroxyurea will vary and will depend on your insurance plan as well as the dosage prescribed. With a SingleCare prescription discount card, Hydroxyurea costs $17.89 for 60, 500mg capsules. The retail price with a free coupon from SingleCare may be cheaper than the cost with insurance.
Medicare Advantage and Medicare Part D prescription drug insurance plans usually provide coverage for Hydroxyurea, but the brand-name version of Hydroxyurea, Hydrea, usually is not. If you don't have coverage for Hydroxyurea, consider using a SingleCare Hydroxyurea coupon for your prescription. With SingleCare, the price of Hydroxyurea is $17.89 for 60, 500mg capsules.
Hydroxyurea is a generic prescription alternative to the brand-name drug, Hydrea. Generic Hydroxyurea is manufactured by Par, Barr, and Leading Pharma. If you have any questions about Hydrea, make sure you search the SingleCare website or app for information and valuable savings coupons.
Hydroxyurea is a generic prescription drug that is used to treat a certain type of leukemia (chronic myeloid leukemia), head and neck cancers, and melanoma (cancer of pigment-creating cells in the skin, eye, or intestines). It is sometimes used off-label for recurrent or inoperable ovarian cancer.
Hydroxyurea blocks the ability of cancer cells to create DNA, so they eventually die off without producing new cancer cells. In addition, Hydroxyurea prevents cancer cells from repairing DNA damage caused by radiation therapy or chemotherapy, making it less likely for cancer cells to rebound from those therapies.
Hydroxyurea is also used to treat sickle cell anemia, a genetic disorder in which the body makes an irregular form of hemoglobin, the molecule that carries oxygen in the red blood cells. This irregular form of hemoglobin causes red blood cells to become misshapen into a sickle-like shape. These misshapen red blood cells carry less oxygen and block other red blood cells. Low oxygen damages the nerves and organs throughout the body.
Hydroxyurea promotes the production of the correct form of hemoglobin, called fetal hemoglobin. With more fetal hemoglobin, red blood cells are less likely to become distorted into a sickle shape and cause problems with oxygen transportation.
Hydroxyurea is taken as a capsule. Dosage is based on body weight.
Common side effects of Hydroxyurea include, but are not limited to, nausea, vomiting, diarrhea, constipation, upset stomach, hair loss, headache, dizziness, drowsiness, and flu-like symptoms. Other side effects of Hydroxyurea include decreased white blood cell counts, decreased reticulocyte counts, and decreased platelet counts. Tell your doctor if you experience serious side effects, or side effects persist or worsen.
Allergic reactions are rare. Watch for important signs of an allergic reaction, including swelling, itching, or rash, and talk to your doctor if you experience what you believe to be an allergic reaction.
Consult your healthcare provider for other possible side effects, warnings, precautions, drug information, and medical advice before starting treatment with Hydroxyurea.
Gerardo Sison, Pharm.D., graduated from the University of Florida. He has worked in both community and hospital settings, providing drug information and medication therapy management services. As a medical writer, he hopes to educate and empower patients to better manage their health and navigate their treatment plans.
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Prescription savings vary by prescription and by pharmacy, and may reach up to 80% off cash price. This is a medical discount plan. This is NOT insurance. This program offers you the opportunity to locate providers of various types of medical services who will offer their services to you at discounted rates. The range of discounts for medical or ancillary services provided under the plan will vary depending on the type of provider and service received. You are fully responsible for paying for all health care services but will be entitled to receive a discount from those health care providers in accordance with the specific pre-negotiated discounted fee schedule. This program does not guarantee the quality of the services or procedures offered by the providers. Except for prescription drugs which you will pay directly to the pharmacy at the time of purchase, all other services received through a program provider will be charged to the credit card on file in your member account. The charge will include an administrative fee for use of the program. Towers Administrators LLC is the licensed discount medical plan organization with its administrative office located at 4510 Cox Road, Suite 111, Glen Allen, VA 23060. SingleCare Services, LLC is the marketer of the discount medical plan organization including its website, singlecare.com, with its corporate office located at 99 High Street, Suite 2800, Boston, MA 02110. For additional information, including an up-to-date list of providers, or assistance with any issue related to program membership, please contact member support any time at www.singlecare.com, or by calling toll-free 844-234-3057, 24 hours, 7 days a week (except major holidays). Pharmacy names, logos, brands, and other trademarks are the property of their respective owners.
Blog articles are not medical advice. They are intended for general informational purposes and are not meant to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. If you think you may have a medical emergency, immediately call your physician or dial 911.
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© 2025 SingleCare Administrators. All rights reserved