Hydrea is a brand-name prescription drug that is used to treat a certain type of leukemia (chronic myeloid leukemia) and head and neck cancers. The active ingredient in Hydrea, hydroxyurea, blocks the ability of cancer cells to produce or use DNA, preventing the cancer cells from growing. Hydroxia, the active ingredient of Hydrea, is also used to treat sickle cell disease. Hydrea normally costs $681.09 at full retail price. A SingleCare Hydrea coupon reduces that price to $17.89.
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SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.
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Prices updated: 02/03/2026
Hydrea is a brand-name prescription drug that is used to treat a certain type of leukemia (chronic myeloid leukemia) and head and neck cancers. The active ingredient in Hydrea, hydroxyurea, blocks the ability of cancer cells to produce or use DNA, preventing the cancer cells from growing. Hydroxia, the active ingredient of Hydrea, is also used to treat sickle cell disease. Hydrea normally costs $681.09 at full retail price. A SingleCare Hydrea coupon reduces that price to $17.89.
Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.
| Pharmacy | Hydroxyurea Retail Price | Hydroxyurea SingleCare Price |
|---|---|---|
| CVS Pharmacy | $78.49 | $28.80 |
| Walmart | $25.00 | $24.20 |
| Walgreens | $18.60 | $12.00 |
| Kroger Pharmacy | $60.00 | $21.00 |
These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.
Hydrea is a brand-name prescription drug that is used to treat a certain type of leukemia (chronic myeloid leukemia) and head and neck cancers. The active ingredient in Hydrea, hydroxyurea, blocks the ability of cancer cells to produce or use DNA, preventing the cancer cells from growing. Hydroxia, the active ingredient of Hydrea, is also used to treat sickle cell disease. Hydrea normally costs $681.09 at full retail price. A SingleCare Hydrea coupon reduces that price to $17.89.
The pharmacy cost of Hydrea will be $681.09. That same prescription will cost $17.89 per 60, 500mg capsules using a SingleCare savings card, which you can use at major pharmacies throughout the country, such as CVS, Target, Longs Drugs, Walmart, and other pharmacies located near you.
The cost of Hydrea with insurance will depend on a number of factors, including the insurance plan’s formulary and the dosage prescribed. With a SingleCare discount card, Hydrea will cost $17.89. That's why it's a good idea to ask your pharmacist to compare your Hydrea insurance copay to your SingleCare Hydrea coupon for the lowest prices. You might save more with SingleCare.
Medicare Advantage and Medicare Part D prescription drug insurance plans usually do not provide coverage for Hydrea, but most Medicare plans will cover the generic version of Hydrea, hydroxyurea. If you don't have coverage for Hydrea, consider using a SingleCare free coupon for your prescription. With SingleCare, the price of Hydrea is $17.89 for 60, 500mg capsules.
Hydrea is a brand-name prescription drug. Generic Hydrea is available as hydroxyurea from different manufacturers including Barr, Leading Pharma, and Par Pharmaceutical. If you have any questions about hydroxyurea, make sure you search the SingleCare website or app for drug information or valuable savings coupons.
The active ingredient in Hydrea, hydroxyurea, blocks the ability of cancer cells to produce DNA needed to replicate, so the cancer cells eventually stop growing and die off. Hydroxyurea also helps prevent the development of sickle-shaped red blood cells in those with sickle cell anemia.
Hydrea is taken as a capsule. Dosage is based on body weight and other factors such as tumor type, severity of disease, and response to treatment.
Common side effects of Hydrea include, but are not limited to, temporary hair loss, headache, drowsiness, dizziness, nausea, vomiting, upset stomach, diarrhea, constipation, and flu symptoms. Consult a healthcare provider if you experience side effects or they persist or worsen.
Serious side effects of Hydrea include low red blood cell counts, low white blood cell counts, and low platelet counts. Seek medical advice from your healthcare provider if you experience fever, body aches, or chills. Some people have experienced cancer, such as leukemia, after taking Hydrea. Skin ulcers have also been reported in some people who have a history of using interferon therapy.
Allergic reactions are rare. Watch for signs of an allergic reaction, including swelling, itching, or rash, and seek immediate medical attention if you experience what you believe to be an allergic reaction.
Tell your healthcare professional if you have a history of kidney or liver problems, HIV, increased uric acid levels, or if you are pregnant or breastfeeding before taking Hydrea.
This is not a complete list of possible side effects. Consult with your physician or pharmacist if you have concerns or questions about side effects or other negative drug interactions.
Gerardo Sison, Pharm.D., graduated from the University of Florida. He has worked in both community and hospital settings, providing drug information and medication therapy management services. As a medical writer, he hopes to educate and empower patients to better manage their health and navigate their treatment plans.
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SingleCare is a prescription discount service that offers free coupons on thousands of prescription drugs. It can be used whether you have insurance, Medicare, Medicaid, or none of the above, but it cannot be combined with insurance.
SingleCare provides transparent drug pricing, so you can compare discounts at pharmacies near you. Browse singlecare.com to find drug discounts, helpful information about your prescription, and resources to help you make informed health decisions.
Prescription savings vary by prescription and by pharmacy, and may reach up to 80% off cash price. This is a medical discount plan. This is NOT insurance. This program offers you the opportunity to locate providers of various types of medical services who will offer their services to you at discounted rates. The range of discounts for medical or ancillary services provided under the plan will vary depending on the type of provider and service received. You are fully responsible for paying for all health care services but will be entitled to receive a discount from those health care providers in accordance with the specific pre-negotiated discounted fee schedule. This program does not guarantee the quality of the services or procedures offered by the providers. Except for prescription drugs which you will pay directly to the pharmacy at the time of purchase, all other services received through a program provider will be charged to the credit card on file in your member account. The charge will include an administrative fee for use of the program. Towers Administrators LLC is the licensed discount medical plan organization with its administrative office located at 4510 Cox Road, Suite 111, Glen Allen, VA 23060. SingleCare Services, LLC is the marketer of the discount medical plan organization including its website, singlecare.com, with its corporate office located at 99 High Street, Suite 2800, Boston, MA 02110. For additional information, including an up-to-date list of providers, or assistance with any issue related to program membership, please contact member support any time at www.singlecare.com, or by calling toll-free 844-234-3057, 24 hours, 7 days a week (except major holidays). Pharmacy names, logos, brands, and other trademarks are the property of their respective owners.
Blog articles are not medical advice. They are intended for general informational purposes and are not meant to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. If you think you may have a medical emergency, immediately call your physician or dial 911.
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© 2026 SingleCare Administrators. All rights reserved