What is Jadenu: Uses, Warnings & Interactions

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep the bottle closed tightly and away from moisture.

Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.

Granule: Sprinkle the granules on soft food (including applesauce or yogurt) immediately before taking it orally.Take the granules at the same time each day on an empty stomach or with a light meal.

Tablet: Swallow the tablet whole with water or other liquids.Take the tablet at the same time each day on an empty stomach or with a light meal.If you have trouble swallowing the whole tablet, it may be crushed and mixed with soft foods (including apple sauce or yogurt) immediately before taking it orally.

Tablet for suspension: Dissolve the tablet in water, orange juice, or apple juice. Mix well and drink the mixture right away. To make sure you get all of the medicine, add more liquid to the glass, and then drink all of it. Do not chew or swallow the tablet.Take the medicine at the same time each day on an empty stomach, at least 30 minutes before you eat.

Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

Tablet: Swallow the tablet whole with water or other liquids.Take the tablet at the same time each day on an empty stomach or with a light meal.If you have trouble swallowing the whole tablet, it may be crushed and mixed with soft foods (including apple sauce or yogurt) immediately before taking it orally.

Tablet for suspension: Dissolve the tablet in water, orange juice, or apple juice. Mix well and drink the mixture right away. To make sure you get all of the medicine, add more liquid to the glass, and then drink all of it. Do not chew or swallow the tablet.Take the medicine at the same time each day on an empty stomach, at least 30 minutes before you eat.

Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.

Granule: Sprinkle the granules on soft food (including applesauce or yogurt) immediately before taking it orally.Take the granules at the same time each day on an empty stomach or with a light meal.

Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep the bottle closed tightly and away from moisture.

You might need to take this medicine on an empty stomach. Take penicillamine or trientine at least 1 hour before eating a meal or 2 hours after eating a meal. Do not eat or drink milk within 1 hour of the time you take this medicine. Ask your doctor or pharmacist if you have questions about what schedule to follow.

Oral routeCarefully follow your doctor's instructions about any special diet.

Your doctor will tell you how much medicine to use. Do not use more than directed.

Do not open or chew trientine capsule. If you get any of this medicine on your skin, wash it off right away.

If you cannot swallow the succimer capsule, you may open it and pour the medicine into a small amount of soft food such as pudding, yogurt, or applesauce. Stir this mixture well and swallow it without chewing. You can also pour the medicine beads into a spoon, swallow the beads, and then drink some fruit drink.

You might need to drink extra water while you are using this medicine.

Oral routeCarefully follow your doctor's instructions about any special diet.

Do not open or chew trientine capsule. If you get any of this medicine on your skin, wash it off right away.

If you cannot swallow the succimer capsule, you may open it and pour the medicine into a small amount of soft food such as pudding, yogurt, or applesauce. Stir this mixture well and swallow it without chewing. You can also pour the medicine beads into a spoon, swallow the beads, and then drink some fruit drink.

Your doctor will tell you how much medicine to use. Do not use more than directed.

You might need to take this medicine on an empty stomach. Take penicillamine or trientine at least 1 hour before eating a meal or 2 hours after eating a meal. Do not eat or drink milk within 1 hour of the time you take this medicine. Ask your doctor or pharmacist if you have questions about what schedule to follow.

You might need to drink extra water while you are using this medicine.

Ask your pharmacist, doctor, or health caregiver about the best way to dispose of any outdated medicine or medicine no longer needed.

Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

Keep all medicine out of the reach of children. Never share your medicine with anyone.

This medicine is not right for everyone. Do not use it if you had an allergic reaction to deferasirox.

Make sure your doctor knows if you have had an allergic reaction to any chelating agent such as penicillamine, succimer, or trientine. Make sure your doctor knows if you are pregnant or breastfeeding. Tell your doctor if you have kidney disease.

Your skin might be more fragile while you are using penicillamine, especially on your shoulders, elbows, knees, toes, or buttocks. Your skin might also heal more slowly than usual. Talk to your doctor before you have any kind of surgery, because your dose of this medicine might need to be changed.

You might need to take your temperature every night when you first start using this medicine.

For people who have diabetes: Succimer may affect the results of some urine tests for ketones (such as Ketostix®). Ask your doctor what kind of ketone test you should use while you are using succimer.

For Wilson€™s disease, you might need to use this medicine for one to three months before you notice any improvement. The symptoms of Wilson€™s disease might get worse when you first start using this medicine. If your symptoms get very bad or keep getting worse, tell your doctor.

Some people have too much heavy metal in their bodies because they were exposed to it, such as in the home or at work. The metal could still be in their surroundings. If this is your situation, then you must get rid of the metal or learn how to protect yourself. This medicine will not protect you from a heavy metal that you are still being exposed to. Find out how you were exposed. Ask your health caregiver about the best ways to get rid of or avoid the heavy metal that caused the problem.

Tell your doctor if you have ever used a chelating agent before.

Make sure any doctor or dentist who treats you knows that you are using this medicine.

Do not stop using this medicine without talking to your doctor first.

Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

Make sure your doctor knows if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, or problems with your blood. Tell your doctor if you are allergic to penicillin.

Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, blood or bone marrow problems, cancer, diabetes, eye problems (including cataracts, glaucoma), hearing problems, or stomach or bowel problems (including ulcers or bleeding).

This medicine can cause the following problems: Kidney problems, including kidney failureLiver problemsStomach or bowel bleeding, ulcer, or perforation (may be life-threatening)Anemia or other problems with blood cell countsSerious skin reactions, including drug reaction with eosinophilia and systemic symptoms (DRESS)Changes in vision or hearing

This medicine may make you bleed, bruise, or get infections more easily. Take precautions to prevent illness and injury. Wash your hands often.

This medicine may make you dizzy. Do not drive or do anything else that could be dangerous until you know how this medicine affects you.

Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

Keep all medicine out of the reach of children. Never share your medicine with anyone.

Rapid weight gain, swelling in your face, hands, ankles, or feet

Unusual bleeding, bruising, or weakness

Do not take antacids that contain aluminum while you are using this medicine.

There are many medicines that can interact with deferasirox. Make sure your doctor knows the names of all the medicines you use, especially the following:Alfentanil, alosetron, aprepitant, buspirone, busulfan, cholestyramine, colesevelam, colestipol, conivaptan, cyclosporine, darifenacin, darunavir, dasatinib, dihydroergotamine, dronedarone, duloxetine, eletriptan, eplerenone, ergotamine, everolimus, felodipine, fentanyl, indinavir, lopinavir, lovastatin, lurasidone, maraviroc, melatonin, midazolam, nisoldipine, paclitaxel, phenobarbital, phenytoin, pimozide, quetiapine, quinidine, ramelteon, repaglinide, rifampicin, ritonavir, saquinavir, sildenafil, simvastatin, sirolimus, tacrine, tacrolimus, theophylline, ticagrelor, tipranavir, tizanidine, tolvaptan, triazolam, vardenafilBirth control pills or patchesBisphosphonate medicineBlood thinner (including warfarin)Coffee or products that contain caffeineNSAID pain medicine (including aspirin, celecoxib, diclofenac, ibuprofen, naproxen)Steroid medicine (including budesonide, fluticasone, prednisolone, prednisone)

This medicine may make you bleed, bruise, or get infections more easily. Take precautions to prevent illness and injury. Wash your hands often.

This medicine may make you dizzy. Do not drive or do anything else that could be dangerous until you know how this medicine affects you.

Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

Keep all medicine out of the reach of children. Never share your medicine with anyone.

You might need to take your temperature every night when you first start using this medicine.

Your skin might be more fragile while you are using penicillamine, especially on your shoulders, elbows, knees, toes, or buttocks. Your skin might also heal more slowly than usual. Talk to your doctor before you have any kind of surgery, because your dose of this medicine might need to be changed.

For people who have diabetes: Succimer may affect the results of some urine tests for ketones (such as Ketostix®). Ask your doctor what kind of ketone test you should use while you are using succimer.

For Wilson€™s disease, you might need to use this medicine for one to three months before you notice any improvement. The symptoms of Wilson€™s disease might get worse when you first start using this medicine. If your symptoms get very bad or keep getting worse, tell your doctor.

Some people have too much heavy metal in their bodies because they were exposed to it, such as in the home or at work. The metal could still be in their surroundings. If this is your situation, then you must get rid of the metal or learn how to protect yourself. This medicine will not protect you from a heavy metal that you are still being exposed to. Find out how you were exposed. Ask your health caregiver about the best ways to get rid of or avoid the heavy metal that caused the problem.

Tell your doctor if you are also using any vitamin, mineral, or iron supplements.

Do not take any other medicine at the same time you take penicillamine. Always allow at least 1 hour between the time you take penicillamine and the time you take other medicines. If you are using a different chelating medicine, ask your doctor.

Make sure your doctor knows if you are also using phenylbutazone or medicine to treat malaria, such as mefloquine, quinine, quinidine, chloroquine, atovaquone/proguanil, Lariam®, Malarone®, Aralen®.

Tell your doctor if you have ever used a chelating agent before.

Make sure your doctor knows if you are also using any other medicines to lower the amount of metal in your body.