Leflunomide is a generic drug used to treat the symptoms of rheumatoid arthritis such as tender or swollen joints and joint stiffness. The most popular brand-name version of Leflunomide is Arava. On average, Leflunomide costs about $368.62 for 30, 20mg tablets of Leflunomide to fill a prescription. However, this cost can be decreased to $21.17 for 30, 20mg tablets of generic Leflunomide with a coupon from SingleCare. These free coupons are easily accessible and can be used at pharmacies like CVS, Walmart, Kroger, and Walgreens.
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SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.
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Prices updated: 12/05/2025
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Leflunomide is a generic drug used to treat the symptoms of rheumatoid arthritis such as tender or swollen joints and joint stiffness. The most popular brand-name version of Leflunomide is Arava. On average, Leflunomide costs about $368.62 for 30, 20mg tablets of Leflunomide to fill a prescription. However, this cost can be decreased to $21.17 for 30, 20mg tablets of generic Leflunomide with a coupon from SingleCare. These free coupons are easily accessible and can be used at pharmacies like CVS, Walmart, Kroger, and Walgreens.
Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.
| Pharmacy | Leflunomide Retail Price | Leflunomide SingleCare Price |
|---|---|---|
| CVS Pharmacy | $123.90 | $30.90 |
| Walmart | $146.40 | $146.40 |
| Walgreens | $128.70 | $128.70 |
| Kroger Pharmacy | $354.60 | $41.10 |
| Albertsons Pharmacy | $236.10 | $67.80 |
These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.
Leflunomide is a generic drug used to treat the symptoms of rheumatoid arthritis such as tender or swollen joints and joint stiffness. The most popular brand-name version of Leflunomide is Arava. On average, Leflunomide costs about $368.62 for 30, 20mg tablets of Leflunomide to fill a prescription. However, this cost can be decreased to $21.17 for 30, 20mg tablets of generic Leflunomide with a coupon from SingleCare. These free coupons are easily accessible and can be used at pharmacies like CVS, Walmart, Kroger, and Walgreens.
Without insurance coverage, the average cash price of Leflunomide may be around $368.62 for 30, 20mg tablets of Leflunomide. However, SingleCare can help you to save on this total with our Leflunomide coupons. Pay a discounted price of $21.17 for 30, 20mg tablets of generic Leflunomide at participating pharmacies such as CVS Pharmacy, Target, Longs Drugs, Walmart Pharmacy, Kroger, and Fry's.
With insurance, your average copay will be based on the type of insurance plan you have and your level of coverage. You can calculate your exact cost by visiting your local pharmacist and asking for assistance or asking for your insurance provider. You may be able to save just as much with SingleCare as you would with your insurance when purchasing Leflunomide pay $21.17 for 30, 20mg tablets of generic Leflunomide when you use SingleCare's free coupons at any local pharmacy.
Medicare typically covers Leflunomide and your copay will range anywhere between $0-$159. When using your savings card, SingleCare may be less expensive than Medicare. Ask your pharmacist to check your SingleCare prescription discount card to compare pricing.
Apotex Corp., KVK-Tech, Inc., and Zydus Pharmaceuticals (USA) Inc. are some of the local manufacturers of Leflunomide. A popular brand-name version of Leflunomide is Arava.
Leflunomide is an FDA-approved disease-modifying anti-rheumatic drug (DMARD) and is used to treat the symptoms of rheumatoid arthritis. This is an autoimmune condition where the immune system fails to recognize the body as itself and attacks the healthy tissues around the joints. This condition causes symptoms such as tender, warm, swollen joints, joint stiffness that is usually worse in the mornings and after inactivity, fatigue, fever, and loss of appetite.
Leflunomide is part of the antirheumatics selective immunosuppressants drug class and works by regulating the immune system and reduces swelling and inflammation in the body.
To determine whether this drug is safe for you, tell your healthcare provider if you have a history of liver disease or hepatitis, a serious or uncontrolled infection, kidney disease, nerve problems, such as neuropathy caused by diabetes, a history of tuberculosis, a weak immune system or bone marrow disorder, or if you are using any drugs that weaken your immune system (such as cancer medicine or steroids).
Because Leflunomide affects your immune system, you should not use this drug if you are pregnant or plan to become pregnant. While taking Leflunomide make sure you use an effective birth control method to avoid pregnancy.
Leflunomide primarily affects your immune system to help treat symptoms so side effects of this drug may include a general feeling of weakness, rashes, mouth ulcers, nausea, diarrhea, stomach pain, headache, abnormal liver function tests, thinning hair, back pain, rash, or high blood pressure.
If you experience signs such as sore throat or fever, any unexplained bruising or bleeding, breathlessness, jaundice, when the eyes and skin turn yellow then you should seek medical attention as soon as possible as these may be signs of an infection.
Leflunomide can cause severe or fatal liver damage. While taking Leflunomide your liver function will need to be tested often, and you may need to stop taking Leflunomide based on the results of these tests.
A healthcare professional can offer medical advice and additional information on other side effects that may occur which were not listed here.
Kristi C. Torres, Pharm.D., is a 2005 graduate of The University of Texas at Austin. Her professional background includes academic teaching roles, district-level management for a nationwide pharmacy chain, and clinic-based pharmacy management. Dr. Torres has a wide range of experience in pharmacy operations and has traveled to many states to open and convert clinic-based pharmacies for one of the largest healthcare systems in the nation.
Currently, she works for Tarrytown Expocare Pharmacy in Austin, Texas, serving the intellectual and developmental disability community. There, she leads the order entry team, overseeing orders from across the country.
Dr. Torres began working in pharmacy at the age of 16 in a small East Texas town. She currently resides in Round Rock, Texas, with her daughter and a Shih-Tzu puppy.
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Prescription savings vary by prescription and by pharmacy, and may reach up to 80% off cash price. This is a medical discount plan. This is NOT insurance. This program offers you the opportunity to locate providers of various types of medical services who will offer their services to you at discounted rates. The range of discounts for medical or ancillary services provided under the plan will vary depending on the type of provider and service received. You are fully responsible for paying for all health care services but will be entitled to receive a discount from those health care providers in accordance with the specific pre-negotiated discounted fee schedule. This program does not guarantee the quality of the services or procedures offered by the providers. Except for prescription drugs which you will pay directly to the pharmacy at the time of purchase, all other services received through a program provider will be charged to the credit card on file in your member account. The charge will include an administrative fee for use of the program. Towers Administrators LLC is the licensed discount medical plan organization with its administrative office located at 4510 Cox Road, Suite 111, Glen Allen, VA 23060. SingleCare Services, LLC is the marketer of the discount medical plan organization including its website, singlecare.com, with its corporate office located at 99 High Street, Suite 2800, Boston, MA 02110. For additional information, including an up-to-date list of providers, or assistance with any issue related to program membership, please contact member support any time at www.singlecare.com, or by calling toll-free 844-234-3057, 24 hours, 7 days a week (except major holidays). Pharmacy names, logos, brands, and other trademarks are the property of their respective owners.
Blog articles are not medical advice. They are intended for general informational purposes and are not meant to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. If you think you may have a medical emergency, immediately call your physician or dial 911.
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© 2025 SingleCare Administrators. All rights reserved