What is Leuprolide: Uses, Warnings & Interactions

How to take Leuprolide

• Injection routeIf you store this medicine at home, keep it at room temperature, away from heat, moisture, and direct light.

• Your doctor will prescribe your exact dose and schedule. This medicine is given as a shot into a muscle or under the skin. Leuprolide injection is given on different schedules for different conditions. It might be given every day, once a month, or every few months.

• Injection routeA nurse or other health provider will give you this medicine.

• Injection routeYou may be taught how to give your medicine at home. Make sure you understand all instructions before giving yourself an injection. Do not use more medicine or use it more often than your doctor tells you to.

• Injection routeYou will be shown the body areas where this shot can be given. Use a different body area each time you give yourself a shot. Keep track of where you give each shot to make sure you rotate body areas.

• Injection routeUse a new needle and syringe each time you inject your medicine.

• This medicine should come with a Medication Guide. Ask your pharmacist for a copy if you do not have one.

• Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.

• Missed dose: Injection routeThis medicine needs to be given on a fixed schedule. If you miss a dose, call your doctor, home health caregiver, or treatment clinic for instructions.

• Injection routeUse a new needle and syringe each time you inject your medicine.

• Missed dose: Injection routeThis medicine needs to be given on a fixed schedule. If you miss a dose, call your doctor, home health caregiver, or treatment clinic for instructions.

• Injection routeYou will be shown the body areas where this shot can be given. Use a different body area each time you give yourself a shot. Keep track of where you give each shot to make sure you rotate body areas.

• Your doctor will prescribe your exact dose and schedule. This medicine is given as a shot into a muscle or under the skin. Leuprolide injection is given on different schedules for different conditions. It might be given every day, once a month, or every few months.

• Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.

• Injection routeYou may be taught how to give your medicine at home. Make sure you understand all instructions before giving yourself an injection. Do not use more medicine or use it more often than your doctor tells you to.

• This medicine should come with a Medication Guide. Ask your pharmacist for a copy if you do not have one.

• Injection routeA nurse or other health provider will give you this medicine.

• Injection routeIf you store this medicine at home, keep it at room temperature, away from heat, moisture, and direct light.

What to do if you miss a dose of Leuprolide

Leuprolide contraindications

• This medicine is not right for everyone. Do not use it if you had an allergic reaction to leuprolide or similar medicines, or if you are pregnant or breastfeeding, or if you have unusual vaginal bleeding.

Leuprolide warnings

• Keep all medicine out of the reach of children. Never share your medicine with anyone.

• It is not safe to take this medicine during pregnancy. It could harm an unborn baby. Tell your doctor right away if you become pregnant. Women who are using this medicine should use birth control that does not contain hormones (including condoms, spermicide).

• Tell your doctor if you have kidney disease, heart failure, diabetes, heart or blood vessel disease, heart rhythm problems (including long QT syndrome), problems with your nervous system, or a history of asthma, sinusitis, drug allergy, brain tumor, depression, mental illness, seizures, or stroke.

• Women: Your menstrual periods should stop, but you might have light bleeding or spotting. If you continue to have heavy bleeding or regular periods, call your doctor.

• This medicine may cause the following problems:Changes in mood or behaviorIncreased risk for seizuresHeart rhythm changesWeaker bones, which may lead to osteoporosisProblems with the urinary tract or spinal cord (in men)Changes in blood sugar levels (in men)Increased risk of heart attack or stroke (in men)

• Your symptoms might get worse when you first start using this medicine, but they should get better as the medicine starts to work. If your condition does not begin to improve after 2 weeks, check with your doctor.

• Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results.

• Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

Leuprolide interactions

• Some medicines can affect how leuprolide works. Tell your doctor if you are using any of the following:Medicine to treat depression (including bupropion, SSRIs)Medicine to treat heart rhythm problemsMedicine to treat seizuresSteroid medicine (including dexamethasone, hydrocortisone, methylprednisolone, prednisolone, prednisone)

• If you are using Lupron Depot® 11.25 mg together with norethindrone acetate, you should also read and understand the information and instructions about using norethindrone. The warnings and precautions on norethindrone will also apply to Lupron Depot® 11.25 mg.

• Women: Your menstrual periods should stop, but you might have light bleeding or spotting. If you continue to have heavy bleeding or regular periods, call your doctor.

• This medicine may cause the following problems:Heart rhythm changesWeaker bones, which may lead to osteoporosisProblems with the urinary tract or spinal cord (in men)Changes in blood sugar levels (in men)Higher risk of heart attack or stroke (in men)

• Your symptoms might get worse when you first start using this medicine, but then they should get better as the medicine starts to work. If your condition does not begin to improve after 2 weeks, call your doctor.

• Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results.

• Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.

• Keep all medicine out of the reach of children. Never share your medicine with anyone.