Leuprolide Coupons & Prices

Leuprolide suppresses the immune system, the first line of defense against infections. So Leuprolide lowers the body's ability to prevent or fight infections or certain types of cancer cells, putting patients at a higher risk of infections and cancer.

Other side effects include diarrhea, headache, nausea, vomiting, stomach pain, joint pain, bone pain, thirst, constipation, shaking, pimples, trouble sleeping, swelling, and anemia. Allergic reactions are rare.

This is not a complete list of possible side effects. Consult with your prescribing physician and pharmacist about possible side effects before starting on Leuprolide.

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Leuprolide coupon at Walgreens Pharmacy
$281.34
$ 278.34
$3 off with signupwith signup

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Leuprolide coupon at Kroger Pharmacy
$372.14
$ 369.14
$3 off with signupwith signup

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Leuprolide coupon at Harris Teeter Pharmacy
$372.14
$ 369.14
$3 off with signupwith signup
Leuprolide coupon at Food Lion Pharmacy
$ 408.00
Leuprolide coupon at Publix Pharmacy
$ 451.09
Leuprolide coupon at Costco Pharmacy
$ 458.00

About SingleCare Pricing

SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.

Any SingleCare bonus savings, including the $3 signup bonus, may only be used once.

Prices updated: 12/19/2025

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About Leuprolide

Leuprolide suppresses the immune system, the first line of defense against infections. So Leuprolide lowers the body's ability to prevent or fight infections or certain types of cancer cells, putting patients at a higher risk of infections and cancer.

Other side effects include diarrhea, headache, nausea, vomiting, stomach pain, joint pain, bone pain, thirst, constipation, shaking, pimples, trouble sleeping, swelling, and anemia. Allergic reactions are rare.

This is not a complete list of possible side effects. Consult with your prescribing physician and pharmacist about possible side effects before starting on Leuprolide.

Leuprolide Price History & Information

Price History for Leuprolide Acetate

1 count, box, 1 kit

Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.

Average 1-Month Prices for Leuprolide Acetate

1 count, box, 1 kit
PharmacyLeuprolide Acetate Retail PriceLeuprolide Acetate SingleCare Price
CVS Pharmacy$767.99$280.13
Walgreens$1607.99$285.08
Kroger Pharmacy$1028.49$372.14

These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.

About Leuprolide

Leuprolide suppresses the immune system, the first line of defense against infections. So Leuprolide lowers the body's ability to prevent or fight infections or certain types of cancer cells, putting patients at a higher risk of infections and cancer.

Other side effects include diarrhea, headache, nausea, vomiting, stomach pain, joint pain, bone pain, thirst, constipation, shaking, pimples, trouble sleeping, swelling, and anemia. Allergic reactions are rare.

This is not a complete list of possible side effects. Consult with your prescribing physician and pharmacist about possible side effects before starting on Leuprolide.

Leuprolide FAQs

How much does Leuprolide cost without insurance?

Leuprolide costs around $930.75 for uninsured customers, but the price of Leuprolide may vary widely depending on the prices set by the hospital or clinic where you get your injection. With a SingleCare Leuprolide coupon, you will pay per 1, 1 kit box for the same injection if the hospital or clinic accepts SingleCare.

How much does Leuprolide cost with insurance?

Your copay for Leuprolide with insurance will vary depending on your plan and the price charged for Leuprolide by the hospital or clinic where you get your injection. However, Leuprolide may be covered by your health insurance as a medical benefit rather than a prescription drug benefit, in which case your copay cost could be as little as $0. Ask the clinic or hospital where you receive Leuprolide injections if they will accept a SingleCare Leuprolide coupon. If they do, you could pay.

Does Medicare cover Leuprolide and how much does it cost?

Leuprolide is usually not covered under Medicare prescription drug plans, but is covered under Medicare Part B as a medical benefit. Ask the clinic or hospital where you receive Leuprolide injections if they will accept a SingleCare Leuprolide coupon. If so, the price for Leuprolide will only be $278.34 for 1, 1 kit box.

Is there a generic of Leuprolide?

Leuprolide is the active ingredient in Eligard, a brand-name prescription drug that treats prostate cancer.

What is Leuprolide?

Leuprolide is a generic drug and the active ingredient in Eligard, a brand-name prescription drug prescribed to men with advanced prostate cancer. Eligard is a palliative treatment, that is, it helps to slow down the growth of the cancer, but it does not cure or eliminate the cancer.

Leuprolide works by reducing male hormones—testosterone and dihydrotestosterone. It does this by blocking the production of male hormones. Leuprolide attaches to cells that act like switches on organs that produce male hormones and essentially turns them off.

Male hormones are responsible for the uncontrolled growth of prostate cancer cells. These hormones attach to proteins on the outside of the cancer cell and “signal” the cell to produce new cancer cells. By blocking the production of male hormones, Leuprolide reduces the chances of individual cancer cells dividing into new cancer cells.

Leuprolide can also prevent the release of female hormones (estrogen) in women. Because of this, it is sometimes prescribed off-label to treat endometriosis (a condition where the inner lining of the uterus, the endometrium, grows on the outside of the uterus) or uterine fibroids which are non-cancerous growths in the uterus. Both conditions are linked to estrogen.

Leuprolide is administered by a healthcare professional as an injection beneath the skin. Each injection provides a continuous release of leuprolide acetate for two, four, or six months.

What are the side effects of Leuprolide?

Common side effects of Leuprolide include, but are not limited to, acne, hot flashes, chills, nausea, constipation, stomach pain, testicle pain, joint pain, muscle pain, insomnia, “feeling bad” (malaise), loss of interest in sex, and impotence. Mental and mood changes include mood swings, depression, and suicidal thoughts.

Serious but rare side effects of Leuprolide include stroke and heart attack.

Allergic reactions are rare but can be severe. Leuprolide can cause severe skin reactions, such as Stevens-Johnson syndrome or toxic epidermal necrolysis, which may require hospitalization. Watch for important signs of an allergic reaction, including swelling, fever, sore throat, rash, peeling, and blistering, and talk to your doctor if you experience what you believe to be an allergic reaction.

Where are Leuprolide coupons from SingleCare accepted?

SingleCare is accepted at most national pharmacies and grocers, including the following:

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