Metafolbic Plus is a brand-name prescription dietary supplement with vitamin B9, vitamin B12, and cysteine. Metafolbic Plus improves memory problems in patients with neurological illnesses, such as Alzheimer's. Prescription Metafolbic Plus costs $96.76 for 30, 6-2-600mg tablets on average, but a SingleCare Metafolbic Plus discount card reduces the price to $67.15 for 30, 6-2-600mg tablets. You can use your SingleCare Metafolbic Plus discount card at large retailers (Target), grocery stores (Harris Teeter), or drugstores (Duane Reade) and save up to 80% on all your dietary supplement and prescription drug needs.
Edit your dosage
30 tablet, 6-2-600mgEdit
Show this free card to your pharmacist.
SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.
Any SingleCare bonus savings, including the $3 signup bonus, may only be used once.
Prices updated: 12/05/2025
Members save the most
4.8 average rating
Metafolbic Plus is a brand-name prescription dietary supplement with vitamin B9, vitamin B12, and cysteine. Metafolbic Plus improves memory problems in patients with neurological illnesses, such as Alzheimer's. Prescription Metafolbic Plus costs $96.76 for 30, 6-2-600mg tablets on average, but a SingleCare Metafolbic Plus discount card reduces the price to $67.15 for 30, 6-2-600mg tablets. You can use your SingleCare Metafolbic Plus discount card at large retailers (Target), grocery stores (Harris Teeter), or drugstores (Duane Reade) and save up to 80% on all your dietary supplement and prescription drug needs.
Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.
| Pharmacy | Metafolbic Plus Retail Price | Metafolbic Plus SingleCare Price |
|---|---|---|
| Walmart | $145.20 | $75.60 |
| Walgreens | $94.50 | $73.20 |
| Kroger Pharmacy | $80.10 | $70.20 |
| Albertsons Pharmacy | $96.60 | $78.60 |
These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.
Metafolbic Plus is a brand-name prescription dietary supplement with vitamin B9, vitamin B12, and cysteine. Metafolbic Plus improves memory problems in patients with neurological illnesses, such as Alzheimer's. Prescription Metafolbic Plus costs $96.76 for 30, 6-2-600mg tablets on average, but a SingleCare Metafolbic Plus discount card reduces the price to $67.15 for 30, 6-2-600mg tablets. You can use your SingleCare Metafolbic Plus discount card at large retailers (Target), grocery stores (Harris Teeter), or drugstores (Duane Reade) and save up to 80% on all your dietary supplement and prescription drug needs.
With a prescription, Metafolbic Plus normally costs $96.76 for 30, 6-2-600mg tablets. With a SingleCare discount card, you pay only $67.15 for 30, 6-2-600mg tablets for that same prescription at many major retailers, including large discount stores, drugstores, and grocery stores conveniently located near you.
Metafolbic Plus is a prescription dietary supplement, but your insurance may not include it on their list of approved drugs. Check with your pharmacist to determine eligibility and your copay costs. You should also ask your pharmacist to compare your copay costs to the price you pay with a SingleCare Metafolbic Plus discount card, which is currently $67.15 for 30, 6-2-600mg tablets. Your SingleCare cost could be lower.
Medicare prescription drug insurance plans are unlikely to cover a Metafolbic Plus prescription. Instead, bring your SingleCare savings card to any participating retailer and you will pay only $67.15 for 30, 6-2-600mg tablets on a Metafolbic Plus prescription.
Metafolbic Plus is a prescription dietary supplement that is a generic alternative to Cerefolin NAC.
All the active ingredients in Metafolbic Plus–methylfolate (vitamin B9), acetylcysteine, and methylcobalamin (vitamin B12)–are widely available in over-the-counter dietary supplements either individually or in combination with other nutrients. Acetylcysteine is typically sold over-the-counter as “NAC.”
Metafolbic Plus is a brand-name prescription dietary supplement. It is prescribed to patients with mild cognitive impairment and memory loss due to Alzheimer's and other neurological illnesses. It is also prescribed to patients with hyperhomocysteinemia, or excess homocysteine, or to patients with a vitamin B12 deficiency that cannot be effectively treated with dietary changes.
Memory loss and cognitive impairment are often due to the death of neurons caused by the oxidizing activities of free radicals. Cysteine clears free radicals from the body and also regulates a chemical in the brain, glutamate, that, in excess, can cause brain damage.
Metafolbic Plus's active ingredients include N-acetylcysteine (NAC, a man-made form of cysteine) and methylfolate (vitamin B9), which is needed by the body to produce cysteine. Metafolbic Plus also includes vitamin B12 (methylcobalamin).
Metafolbic Plus is taken as a tablet once per day.
Metafolbic Plus side effects are rare. Uncommon side effects include but are not limited to rash, discomfort, diarrhea, and depression.
SingleCare is accepted at most national pharmacies and grocers, including the following:
Health education, drug info, wellness & more
