Methylprednisolone Acetate is an anti-inflammatory prescription drug injection used when oral corticosteroids are not adequate, such as localized swelling, urgent cases, or conditions that are not responding to oral corticosteroids. Methylprednisolone Acetate belongs to a family of drugs called corticosteroids that suppress the immune system and so reduce the swelling due to an immune reaction. Methylprednisolone Acetate is often injected by a healthcare professional at a clinic or hospital. On average, Methylprednisolone Acetate costs $50.34 but you could pay $12.41 for 1, 1ml of 40mg/ml vial with a free SingleCare Methylprednisolone Acetate coupon.
Edit your dosage
1 vial, 1ml of 40mg/mlEdit
You have 0.00 in available bonus savings. Bonus savings will be automatically applied to your next eligible prescription fill.
Show this free card to your pharmacist.
SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.
Any SingleCare bonus savings, including the $3 signup bonus, may only be used once.
Prices updated: 05/05/2026
Methylprednisolone Acetate is an anti-inflammatory prescription drug injection used when oral corticosteroids are not adequate, such as localized swelling, urgent cases, or conditions that are not responding to oral corticosteroids. Methylprednisolone Acetate belongs to a family of drugs called corticosteroids that suppress the immune system and so reduce the swelling due to an immune reaction. Methylprednisolone Acetate is often injected by a healthcare professional at a clinic or hospital. On average, Methylprednisolone Acetate costs $50.34 but you could pay $12.41 for 1, 1ml of 40mg/ml vial with a free SingleCare Methylprednisolone Acetate coupon.
Methylprednisolone Acetate is an anti-inflammatory prescription drug injection used when oral corticosteroids are not adequate, such as localized swelling, urgent cases, or conditions that are not responding to oral corticosteroids. Methylprednisolone Acetate belongs to a family of drugs called corticosteroids that suppress the immune system and so reduce the swelling due to an immune reaction. Methylprednisolone Acetate is often injected by a healthcare professional at a clinic or hospital. On average, Methylprednisolone Acetate costs $50.34 but you could pay $12.41 for 1, 1ml of 40mg/ml vial with a free SingleCare Methylprednisolone Acetate coupon.
The cost of Methylprednisolone Acetate will vary. On average, however, generic Methylprednisolone Acetate costs $50.34. If you're paying cash for Methylprednisolone Acetate, you can purchase Methylprednisolone Acetate for $12.41 with a SingleCare discount card.
Check with your pharmacist to figure out your copay cost for Methylprednisolone Acetate under your insurance plan. When you do, remember that with a SingleCare savings card, Methylprednisolone Acetate costs $12.41. To get the best price on Methylprednisolone Acetate, compare your insurance copay to SingleCare’s discount.
Medicare prescription drug plans usually do not cover Methylprednisolone Acetate or its brand-name version Depo-Medrol. For patients who are not covered, SingleCare offers coupons for both Methylprednisolone Acetate and many of its brand-name versions. Your cost for 1, 1ml of 40mg/ml vial of Methylprednisolone Acetate could be $12.41 with a SingleCare Methylprednisolone Acetate coupon.
Methylprednisolone Acetate is a generic prescription drug. The brand-name version is Depo-Medrol manufactured by Pfizer.
Methylprednisolone Acetate is a generic anti-inflammatory prescription corticosteroid injection used to alleviate swelling in local areas, such as joints or the skin, or in urgent conditions or those that have not responded to oral corticosteroids.
Situations requiring a direct, localized injection include rheumatoid arthritis, carpal tunnel syndrome, bursitis, lupus, psoriasis, and tendon problems. These injections will be performed by a healthcare professional, usually a specialist such as a dermatologist or an orthopedist, in a clinic or hospital.
Urgent situations requiring an intramuscular injection include multiple sclerosis flare-ups, intestinal conditions which cause swelling, severe allergic reactions, severe drug reactions, adrenal gland problems, and respiratory illnesses. Methylprednisolone Acetate is also used to relieve symptoms in patients with leukemia or lymphoma.
Some situations, such as swelling in the eye, are normally treated with topical steroids, but Methylprednisolone Acetate is used when those topical treatments don't resolve the swelling.
Methylprednisolone Acetate is a corticosteroid, which decreases swelling by reducing the immune response to injury, allergens, or infection. Because Methylprednisolone Acetate suppresses the immune response, secondary infections are a risk.
Most people will experience side effects when taking Methylprednisolone Acetate. Methylprednisolone Acetate suppresses the immune system, so the most serious side effects of Methylprednisolone Acetate are secondary infections.
The most common side effect will be site reactions to the injection such as redness and pain. Common side effects of Methylprednisolone Acetate also include but are not limited to nausea, vomiting, heartburn, headache, sweating, acne, fluid retention, muscle weakness, thinning skin, hair growth, and a rise in blood sugar.
Mental and mood changes can range from mild to serious mood changes. Allergic reactions include hives, facial swelling, and difficulty breathing, although facial swelling is also a common non-allergic side effect of taking steroids.
This is not a complete list of side effects that may occur. Consult with your physician about any concerns you may have with side effects.
SingleCare is accepted at most national pharmacies and grocers, including the following:
Health education, drug info, wellness & more
SingleCare is a prescription discount service that offers free coupons on thousands of prescription drugs. It can be used whether you have insurance, Medicare, Medicaid, or none of the above, but it cannot be combined with insurance.
SingleCare provides transparent drug pricing, so you can compare discounts at pharmacies near you. Browse singlecare.com to find drug discounts, helpful information about your prescription, and resources to help you make informed health decisions.
Prescription savings vary by prescription and by pharmacy, and may reach up to 80% off cash price. This is a medical discount plan. This is NOT insurance. This program offers you the opportunity to locate providers of various types of medical services who will offer their services to you at discounted rates. The range of discounts for medical or ancillary services provided under the plan will vary depending on the type of provider and service received. You are fully responsible for paying for all health care services but will be entitled to receive a discount from those health care providers in accordance with the specific pre-negotiated discounted fee schedule. This program does not guarantee the quality of the services or procedures offered by the providers. Except for prescription drugs which you will pay directly to the pharmacy at the time of purchase, all other services received through a program provider will be charged to the credit card on file in your member account. The charge will include an administrative fee for use of the program. Towers Administrators LLC is the licensed discount medical plan organization with its administrative office located at 4510 Cox Road, Suite 111, Glen Allen, VA 23060. SingleCare Services, LLC is the marketer of the discount medical plan organization including its website, singlecare.com, with its corporate office located at 99 High Street, Suite 2800, Boston, MA 02110. For additional information, including an up-to-date list of providers, or assistance with any issue related to program membership, please contact member support any time at www.singlecare.com, or by calling toll-free 844-234-3057, 24 hours, 7 days a week (except major holidays). Pharmacy names, logos, brands, and other trademarks are the property of their respective owners.
Blog articles are not medical advice. They are intended for general informational purposes and are not meant to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. If you think you may have a medical emergency, immediately call your physician or dial 911.
© 2026 SingleCare Administrators. All rights reserved
© 2026 SingleCare Administrators. All rights reserved