What is Midazolam Hcl (Pf): Uses, Warnings & Interactions

Updated May 14, 2025  •  Published Dec 30, 2020

Midazolam Hcl (Pf) overview

BRAND NAMES:

  • Midazolam HCl Novaplus, PremierPro Rx Midazolam

Generic Names:

  • Midazolam Hcl (Pf)

Uses:

  • Treats status epilepticus (continuous seizures). Also used to relieve anxiety before surgery.

Therapeutic Classes:

  • Anticonvulsant

Forms:

  • Injectable

How it’s taken:

  • By injection

What is Midazolam Hcl (Pf) used for?

What form(s) does Midazolam Hcl (Pf) come in

  • Injectable

What are common Midazolam Hcl (Pf) doses?

  • Vial 2ML of 2MG/2ML

  • Vial 1ML of 5MG/ML

  • Vial 5ML of 5MG/5ML

  • Vial 2ML of 10MG/2ML

  • Syringe 2ML of 2MG/2ML

  • Syringe 1ML of 5MG/ML

  • Crtrdg-Ndl 1ML of 5MG/ML

Common Midazolam Hcl (Pf) prescriptions

  • Midazolam HCl (PF)
    1ml of 5mg/ml crtrdg-ndl

  • Midazolam HCl (PF)
    1ml of 5mg/ml syringe

  • Midazolam HCl (PF)
    2ml of 10mg/2ml syringe

  • Midazolam HCl (PF)
    2ml of 2mg/2ml syringe

  • Midazolam HCl (PF)
    1ml of 5mg/ml vial

  • Midazolam HCl (PF)
    2ml of 10mg/2ml vial

  • Midazolam HCl (PF)
    2ml of 2mg/2ml vial

  • Midazolam HCl (PF)
    5ml of 5mg/5ml vial

How to take Midazolam Hcl (Pf)

  • After you receive a shot of this medicine, your doctor will watch you closely to make sure it is working properly and to check for unwanted effects.

  • Injection routeA nurse or other health provider will give you this medicine.

  • Injection routeYour doctor will prescribe your exact dose and tell you how often it should be given. This medicine is given as a shot into one of your muscles.

  • After you receive midazolam, you will be watched closely to make sure the medicine is working. Your breathing, blood pressure, nervous system, and heart will also be watched closely to make sure the medicine is not causing unwanted side effects.

  • After you receive a shot of this medicine, your doctor will watch you closely to make sure it is working properly and to check for unwanted effects.

  • Injection routeA nurse or other health provider will give you this medicine.

  • Injection routeYour doctor will prescribe your exact dose and tell you how often it should be given. This medicine is given as a shot into one of your muscles.

  • After you receive midazolam, you will be watched closely to make sure the medicine is working. Your breathing, blood pressure, nervous system, and heart will also be watched closely to make sure the medicine is not causing unwanted side effects.

What to do if you miss a dose of Midazolam Hcl (Pf)

Midazolam Hcl (Pf) contraindications

  • This medicine is not right for everyone. You should not receive it if you had an allergic reaction to midazolam.

Midazolam Hcl (Pf) warnings

  • Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, heart failure, lung or breathing problems (including COPD), low blood pressure, eye or vision problems (including glaucoma), or a history of alcohol or drug abuse.

  • The time it takes for the medicine to wear off varies with each person. However, it may take longer for older adults to recover from the medicine's effects.

  • Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.

  • This medicine may make you dizzy or drowsy. Do not drive or do anything else that could be dangerous until you know how this medicine affects you.

  • This medicine may cause respiratory depression (serious breathing problem that can be life-threatening), especially when used with narcotic pain medicines.

Midazolam Hcl (Pf) interactions

  • Some medicines can affect how midazolam works. Tell your doctor if you are using cimetidine, diltiazem, erythromycin, itraconazole, ketoconazole, or verapamil.

  • The time it takes for the medicine to wear off varies with each person. However, it may take longer for older adults to recover from the medicine's effects.

  • Midazolam may make you drowsy or dizzy for 1 or 2 days after you receive it. Wait 24 hours or until the effects of the medicine have worn off (whichever is longer) before driving or using machinery.

  • Do not drink alcohol while you are using this medicine.

  • Tell your doctor if you use anything else that makes you sleepy. Some examples are allergy medicine, narcotic pain medicine, and alcohol. Tell your doctor if you are also using droperidol, fentanyl, meperidine, morphine, or secobarbital.

Midazolam Hcl (Pf) side effects

Serious Side Effects

  • Extreme tiredness or weakness, slow heartbeat, problems with coordination or walking

  • Blurred vision or other change in vision, eye pain

  • Blue lips, fingernails, or skin, trouble breathing, chest pain

  • Agitation, tremor, restlessness, jerky muscle movement you cannot control (often in your face, tongue, or jaw)

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

Less Serious Side Effects

  • Headache, dizziness

  • Dizziness, drowsiness

  • Nausea

  • Pain, itching, burning, swelling, or a lump where the shot is given

  • Drowsiness that continues after 2 days

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