Xeljanz XR is a brand-name medication used to treat rheumatoid arthritis, a condition in which the body's immune system mistakenly attacks cells in the joints, causing swelling, stiffness, and pain. The active ingredient in Xeljanz XR, tofacitinib, suppresses the body’s inflammatory response in order to reduce symptoms of rheumatoid arthritis. Xeljanz XR can also be used to treat psoriatic arthritis and ulcerative colitis. The average retail price of Xeljanz XR may be very high at approximately $7,521.41 for 30, 11mg tablet extended release 24 hours. A SingleCare Xeljanz XR coupon may reduce the price to $5,455.32 for 30, 11mg tablet extended release 24 hours.
Edit your dosage
2 tablet extended release 24 hour, 11mgEdit
Unlock members-only prices.Free signup.
You have 0.00 in available bonus savings. Bonus savings will be automatically applied to your next eligible prescription fill.
Show this free card to your pharmacist.

Save an extra $3 on any eligible prescription! Sign up for free
Members can save even more
and it's free to join
SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.
Any SingleCare bonus savings, including the $3 signup bonus, may only be used once.
Prices updated: 12/06/2025
Members save the most
Xeljanz XR is a brand-name medication used to treat rheumatoid arthritis, a condition in which the body's immune system mistakenly attacks cells in the joints, causing swelling, stiffness, and pain. The active ingredient in Xeljanz XR, tofacitinib, suppresses the body’s inflammatory response in order to reduce symptoms of rheumatoid arthritis. Xeljanz XR can also be used to treat psoriatic arthritis and ulcerative colitis. The average retail price of Xeljanz XR may be very high at approximately $7,521.41 for 30, 11mg tablet extended release 24 hours. A SingleCare Xeljanz XR coupon may reduce the price to $5,455.32 for 30, 11mg tablet extended release 24 hours.
Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.
| Pharmacy | Xeljanz Xr Retail Price | Xeljanz Xr SingleCare Price |
|---|---|---|
| Walmart | $7287.90 | $6658.20 |
| Kroger Pharmacy | $7287.90 | $5458.20 |
These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.
Xeljanz XR is a brand-name medication used to treat rheumatoid arthritis, a condition in which the body's immune system mistakenly attacks cells in the joints, causing swelling, stiffness, and pain. The active ingredient in Xeljanz XR, tofacitinib, suppresses the body’s inflammatory response in order to reduce symptoms of rheumatoid arthritis. Xeljanz XR can also be used to treat psoriatic arthritis and ulcerative colitis. The average retail price of Xeljanz XR may be very high at approximately $7,521.41 for 30, 11mg tablet extended release 24 hours. A SingleCare Xeljanz XR coupon may reduce the price to $5,455.32 for 30, 11mg tablet extended release 24 hours.
Xeljanz XR can be an expensive prescription drug. At most pharmacies, the full cost of Xeljanz XR can be $7,521.41 for 30, 11mg tablet extended release 24 hours. That same prescription may cost $5,455.32 for 30, 11mg tablet extended release 24 hours using a SingleCare savings card, which can be used at major pharmacies throughout the country.
The copay cost of Xeljanz XR varies greatly depending on your insurance plan. With SingleCare, Xeljanz XR may be reduced to a cost of $5,455.32 for 30, 11mg tablet extended release 24 hours. Ask your pharmacist to compare your cost of Xeljanz XR with insurance to your cost with a SingleCare Xeljanz XR coupon. Your savings with SingleCare may be considerably greater.
Most Medicare Advantage and Medicare Part D plans provide coverage for Xeljanz XR, but the copay can still be high. Instead, you can use a SingleCare Xeljanz XR coupon for your prescription. With SingleCare, the lowest price of Xeljanz XR may be reduced to $5,455.32 for 30, 11mg tablet extended release 24 hours.
Xeljanz XR is a brand-name drug that is not currently available in a generic alternative.
Xeljanz XR is a brand-name extended-release drug used to treat moderate to severe rheumatoid arthritis, a condition in which the body's immune system attacks healthy cells in the joints, causing swelling, stiffness, and pain. The active ingredient in Xeljanz XR, tofacitinib, interferes with the substances that signal the immune system to attack the body’s own cells. The result is a slowing down or suppression of the body’s immune response in order to decrease inflammation. Xeljanz XR can treat rheumatoid arthritis, psoriatic arthritis, and ulcerative colitis. Xeljanz XR is prescribed to rheumatoid arthritis patients who have not responded to methotrexate, a less-expensive immune suppressant.
Common side effects include upper respiratory tract infection, urinary tract infection, headache, diarrhea, fatigue, nausea, shortness of breath, and high blood pressure.
Xeljanz XR suppresses the immune system and lowers the body's ability to prevent or fight infections. Patients with risk factors like active infections, particularly tuberculosis, should not take Xeljanz XR unless approved by a prescribing physician. Immune suppression can increase the risk of infections and certain types of cancer, such as skin cancer or lymphoma in certain people.
Other serious side effects include blood clots and tears in the stomach or intestines.
Allergic reactions can be severe and present as skin rash, itching, swelling, or hives. Immediately discontinue using Xeljanz XR at the first sign of an allergic reaction.
This is not a complete list of adverse reactions. Consult with your prescribing doctor or pharmacist about other side effects, warnings, and precautions before starting treatment with Xeljanz XR.
Gerardo Sison, Pharm.D., graduated from the University of Florida. He has worked in both community and hospital settings, providing drug information and medication therapy management services. As a medical writer, he hopes to educate and empower patients to better manage their health and navigate their treatment plans.
...SingleCare is accepted at most national pharmacies and grocers, including the following:
Health education, drug info, wellness & more
Prescription savings vary by prescription and by pharmacy, and may reach up to 80% off cash price. This is a medical discount plan. This is NOT insurance. This program offers you the opportunity to locate providers of various types of medical services who will offer their services to you at discounted rates. The range of discounts for medical or ancillary services provided under the plan will vary depending on the type of provider and service received. You are fully responsible for paying for all health care services but will be entitled to receive a discount from those health care providers in accordance with the specific pre-negotiated discounted fee schedule. This program does not guarantee the quality of the services or procedures offered by the providers. Except for prescription drugs which you will pay directly to the pharmacy at the time of purchase, all other services received through a program provider will be charged to the credit card on file in your member account. The charge will include an administrative fee for use of the program. Towers Administrators LLC is the licensed discount medical plan organization with its administrative office located at 4510 Cox Road, Suite 111, Glen Allen, VA 23060. SingleCare Services, LLC is the marketer of the discount medical plan organization including its website, singlecare.com, with its corporate office located at 99 High Street, Suite 2800, Boston, MA 02110. For additional information, including an up-to-date list of providers, or assistance with any issue related to program membership, please contact member support any time at www.singlecare.com, or by calling toll-free 844-234-3057, 24 hours, 7 days a week (except major holidays). Pharmacy names, logos, brands, and other trademarks are the property of their respective owners.
Blog articles are not medical advice. They are intended for general informational purposes and are not meant to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. If you think you may have a medical emergency, immediately call your physician or dial 911.
© 2025 SingleCare Administrators. All rights reserved
© 2025 SingleCare Administrators. All rights reserved