Oxycodone-Acetaminophen is a generic prescription drug used to treat moderate to severe pain. It may be prescribed when other treatment methods haven’t successfully relieved pain. The brand names of Oxycodone-Acetaminophen include Percocet and Endocet. Oxycodone-Acetaminophen contains a combination of an opioid called oxycodone, and an analgesic called acetaminophen. The average retail price of Oxycodone-Acetaminophen is $24.84 for 12, 5-325mg tablets. A SingleCare Oxycodone-Acetaminophen coupon may help reduce that price to $10.38 for 12, 5-325mg tablets.
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SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.
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Prices updated: 12/05/2025
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Oxycodone-Acetaminophen is a generic prescription drug used to treat moderate to severe pain. It may be prescribed when other treatment methods haven’t successfully relieved pain. The brand names of Oxycodone-Acetaminophen include Percocet and Endocet. Oxycodone-Acetaminophen contains a combination of an opioid called oxycodone, and an analgesic called acetaminophen. The average retail price of Oxycodone-Acetaminophen is $24.84 for 12, 5-325mg tablets. A SingleCare Oxycodone-Acetaminophen coupon may help reduce that price to $10.38 for 12, 5-325mg tablets.
Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.
| Pharmacy | Oxycodone-Acetaminophen Retail Price | Oxycodone-Acetaminophen SingleCare Price |
|---|---|---|
| CVS Pharmacy | $20.28 | $20.04 |
| Walmart | $22.08 | $14.40 |
| Walgreens | $19.99 | $15.52 |
| Kroger Pharmacy | $15.27 | $13.16 |
| Albertsons Pharmacy | $33.72 | $11.28 |
These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.
Oxycodone-Acetaminophen is a generic prescription drug used to treat moderate to severe pain. It may be prescribed when other treatment methods haven’t successfully relieved pain. The brand names of Oxycodone-Acetaminophen include Percocet and Endocet. Oxycodone-Acetaminophen contains a combination of an opioid called oxycodone, and an analgesic called acetaminophen. The average retail price of Oxycodone-Acetaminophen is $24.84 for 12, 5-325mg tablets. A SingleCare Oxycodone-Acetaminophen coupon may help reduce that price to $10.38 for 12, 5-325mg tablets.
The average retail cost of Oxycodone-Acetaminophen is $24.84 for 12, 5-325mg tablets. However, the price without insurance can vary depending on the pharmacy, the quantity and strength prescribed, and other factors. Without insurance, the cost of your prescription can be high. Using a SingleCare prescription discount card may help lower the price at participating pharmacies across the country.
The cost of Oxycodone-Acetaminophen with insurance varies depending on the insurance plan. Consult your insurance company or pharmacy to determine your potential copay or coinsurance amount for your prescription. The price may also depend on your coverage stage, pharmacy, and dosage prescribed. In some cases, the cost with prescription discount cards may be lower than your insurance copay.
Medicare prescription insurance plans may cover Oxycodone-Acetaminophen since it is a generic medication. Check your Medicare Advantage or Medicare Part D prescription drug insurance plan to see if they provide coverage for Oxycodone-Acetaminophen. If you don’t have Medicare coverage, a SingleCare Oxycodone-Acetaminophen coupon may help lower the total cash price of your Oxycodone-Acetaminophen prescription.
The brand names of Oxycodone-Acetaminophen include Percocet, Endocet, Roxicet, and Primalev. Oxycodone-Acetaminophen is a generic prescription drug manufactured by various pharmaceutical companies.
Oxycodone-Acetaminophen is a generic prescription drug used to relieve moderate to severe pain. It may be prescribed for people who are not experiencing pain relief using non-opioid drugs or other treatments. Oxycodone-Acetaminophen is a combination medication that contains an opioid and an analgesic.
Oxycodone is an opioid that binds to certain receptors involved with pain. Acetaminophen is an analgesic or pain reliever that is believed to stop the production of certain chemicals that promote pain. Acetaminophen is also an antipyretic or fever reducer.
Oxycodone-Acetaminophen is usually taken as a tablet. The dosage may vary depending on the severity of the pain. However, the lowest effective dosage is recommended to reduce the risk of severe side effects, withdrawal symptoms, and dependence.
Oxycodone-Acetaminophen is a Schedule II controlled substance that has a high risk of misuse, abuse, and dependence. It should only be used under the supervision of a healthcare provider.
The most common side effects of Oxycodone-Acetaminophen include drowsiness, dizziness, lightheadedness, nausea, and vomiting. Other possible side effects include confusion, anxiety, tremor, indigestions, dry mouth, depression, and insomnia. Consult a doctor or pharmacist if side effects develop, persist, or worsen.
Severe side effects of Oxycodone-Acetaminophen include respiratory depression (slowed breathing), low blood pressure (hypotension), and allergic reactions. Seek immediate medical attention if you experience symptoms or signs of an allergic reaction, such as hives, rash, swelling of the face or throat, or trouble breathing.
{{drug} has a risk of abuse and misuse. An overdose on Oxycodone-Acetaminophen can lead to slowed breathing, low blood pressure, seizures, unconsciousness, coma, or death. Prolonged use of Oxycodone-Acetaminophen followed by abrupt discontinuation may lead to withdrawal symptoms, such as restlessness, chills, irritability, and weakness.
This is not a complete list of side effects. Consult your doctor or pharmacist for medical advice about possible side effects, potential drug interactions, and other precautions before taking this medicine.
Yes, there is an extended-release version of Oxycodone-Acetaminophen. The brand name of extended-release Oxycodone-Acetaminophen is Xartemis XR, which is prescribed to be taken every 12 hours. The active ingredients are slowly released throughout the day to provide consistent pain relief. As a result, the effects of the extended-release form last longer than those of the immediate-release form.
Gerardo Sison, Pharm.D., graduated from the University of Florida. He has worked in both community and hospital settings, providing drug information and medication therapy management services. As a medical writer, he hopes to educate and empower patients to better manage their health and navigate their treatment plans.
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Prescription savings vary by prescription and by pharmacy, and may reach up to 80% off cash price. This is a medical discount plan. This is NOT insurance. This program offers you the opportunity to locate providers of various types of medical services who will offer their services to you at discounted rates. The range of discounts for medical or ancillary services provided under the plan will vary depending on the type of provider and service received. You are fully responsible for paying for all health care services but will be entitled to receive a discount from those health care providers in accordance with the specific pre-negotiated discounted fee schedule. This program does not guarantee the quality of the services or procedures offered by the providers. Except for prescription drugs which you will pay directly to the pharmacy at the time of purchase, all other services received through a program provider will be charged to the credit card on file in your member account. The charge will include an administrative fee for use of the program. Towers Administrators LLC is the licensed discount medical plan organization with its administrative office located at 4510 Cox Road, Suite 111, Glen Allen, VA 23060. SingleCare Services, LLC is the marketer of the discount medical plan organization including its website, singlecare.com, with its corporate office located at 99 High Street, Suite 2800, Boston, MA 02110. For additional information, including an up-to-date list of providers, or assistance with any issue related to program membership, please contact member support any time at www.singlecare.com, or by calling toll-free 844-234-3057, 24 hours, 7 days a week (except major holidays). Pharmacy names, logos, brands, and other trademarks are the property of their respective owners.
Blog articles are not medical advice. They are intended for general informational purposes and are not meant to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. If you think you may have a medical emergency, immediately call your physician or dial 911.
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© 2025 SingleCare Administrators. All rights reserved