Endocet is a brand-name prescription combination drug that treats moderate to moderately severe pain. The active ingredients in Endocet are oxycodone and acetaminophen. Oxycodone is an opioid that blocks pain signals to the brain. Acetaminophen reduces chemicals in the body that cause pain and swelling. Endocet price averages $54.04, but a SingleCare Endocet coupon lowers that price down to $10.38 per 12, 5-325mg tablets.
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SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.
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Prices updated: 12/05/2025
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Endocet is a brand-name prescription combination drug that treats moderate to moderately severe pain. The active ingredients in Endocet are oxycodone and acetaminophen. Oxycodone is an opioid that blocks pain signals to the brain. Acetaminophen reduces chemicals in the body that cause pain and swelling. Endocet price averages $54.04, but a SingleCare Endocet coupon lowers that price down to $10.38 per 12, 5-325mg tablets.
Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.
| Pharmacy | Oxycodone-Acetaminophen Retail Price | Oxycodone-Acetaminophen SingleCare Price |
|---|---|---|
| CVS Pharmacy | $20.28 | $20.04 |
| Walmart | $22.08 | $14.40 |
| Walgreens | $19.99 | $15.52 |
| Kroger Pharmacy | $15.27 | $13.16 |
| Albertsons Pharmacy | $33.72 | $11.28 |
These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.
Endocet is a brand-name prescription combination drug that treats moderate to moderately severe pain. The active ingredients in Endocet are oxycodone and acetaminophen. Oxycodone is an opioid that blocks pain signals to the brain. Acetaminophen reduces chemicals in the body that cause pain and swelling. Endocet price averages $54.04, but a SingleCare Endocet coupon lowers that price down to $10.38 per 12, 5-325mg tablets.
Without insurance, customers can expect to pay $54.04 for Endocet, but this price may vary. With a SingleCare discount card, the cost of Endocet drops to $10.38 per 12, 5-325mg tablets.
The copay cost of Endocet with insurance varies by plan. With a SingleCare savings card, Endocet costs $10.38. This may save you more money than using insurance, so have your pharmacist compare prices with your SingleCare Endocet coupon first before you overpay for Endocet.
Medicare-eligible patients are covered for their Endocet prescription. Patients without Medicare can instead rely on their SingleCare Endocet coupon for consistent savings. Our free and reusable coupons are accepted at participating like Longs Drugs, Kroger, and Duane Reade pharmacies.
Endocet is a brand-name prescription drug. The generic version of Endocet is oxycodone-acetaminophen, and is available from Par, Apotex, Dr. Reddy's, and other generic manufacturers.
Endocet (oxycodone and acetaminophen) is a brand-name prescription drug that relieves moderate to moderately severe pain. Oxycodone is an opioid that binds to pain receptors in the brain, so pain signals to the brain are either partly blocked or completely stopped. Acetaminophen belongs to a class of drugs called non-steroidal anti-inflammatory drugs (NSAIDs) which reduce chemicals in the body that cause pain and swelling.
Endocet is taken as a tablet every six hours. The dose will depend on the severity of the pain. Effects should be evident within an hour of taking Endocet.
Oxycodone is an opioid, so commonly experienced side effects will include sedation, drowsiness, dizziness, and lightheadedness. Mental and mood changes caused by oxycodone include mental clouding, stupor, euphoria, unusual thoughts, unusual behaviors, anxiety, nervousness, depression, and suicide. Other common side effects of Endocet include, but are not limited to, dry mouth, headache, nausea, vomiting, constipation, weakness, itching, upset stomach, sweating, liver problems, blurred vision, ringing in the ears, and problems with urination.
Oxycodone is an addictive drug that is often abused. Overdosing on Endocet will slow down breathing, lower blood pressure, and could result in seizures, unconsciousness, coma, or death. Endocet dependence can occur within a few days, but if Endocet is taken for a few weeks, discontinuation of Endocet will have withdrawal symptoms.
Allergic reactions are very rare, but acetaminophen can in very rare cases cause serious allergic reactions such as Stevens-Johnson syndrome or toxic epidermal necrolysis, which are dangerous and life-threatening skin reactions over the entire body involving swelling, blistering, peeling, skin death, and fever.
This is not a complete list of the Endocet side effects. Consult with your doctor or pharmacist about possible side effects before taking this medicine.
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Prescription savings vary by prescription and by pharmacy, and may reach up to 80% off cash price. This is a medical discount plan. This is NOT insurance. This program offers you the opportunity to locate providers of various types of medical services who will offer their services to you at discounted rates. The range of discounts for medical or ancillary services provided under the plan will vary depending on the type of provider and service received. You are fully responsible for paying for all health care services but will be entitled to receive a discount from those health care providers in accordance with the specific pre-negotiated discounted fee schedule. This program does not guarantee the quality of the services or procedures offered by the providers. Except for prescription drugs which you will pay directly to the pharmacy at the time of purchase, all other services received through a program provider will be charged to the credit card on file in your member account. The charge will include an administrative fee for use of the program. Towers Administrators LLC is the licensed discount medical plan organization with its administrative office located at 4510 Cox Road, Suite 111, Glen Allen, VA 23060. SingleCare Services, LLC is the marketer of the discount medical plan organization including its website, singlecare.com, with its corporate office located at 99 High Street, Suite 2800, Boston, MA 02110. For additional information, including an up-to-date list of providers, or assistance with any issue related to program membership, please contact member support any time at www.singlecare.com, or by calling toll-free 844-234-3057, 24 hours, 7 days a week (except major holidays). Pharmacy names, logos, brands, and other trademarks are the property of their respective owners.
Blog articles are not medical advice. They are intended for general informational purposes and are not meant to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. If you think you may have a medical emergency, immediately call your physician or dial 911.
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© 2025 SingleCare Administrators. All rights reserved