Refresh Optive Advanced is a scientifically advanced eye lubricant that is used to treat dry eye symptoms. This brand-name drug is available for purchase with a prescription or as an over-the-counter medication. Currently, there are no generic versions of Refresh Optive Advanced available. The average price of Refresh Optive Advanced is about $19.16 per 10, 0.5-1-0.5% solution (quantity in ml)s. To save on this price you can use a Refresh Optive Advanced coupon from SingleCare and pay as little as $12.46 for 10, 0.5-1-0.5% solution (quantity in ml)s. Our coupons are accepted at any participating pharmacy in the United States.
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SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.
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Prices updated: 05/04/2026
Refresh Optive Advanced is a scientifically advanced eye lubricant that is used to treat dry eye symptoms. This brand-name drug is available for purchase with a prescription or as an over-the-counter medication. Currently, there are no generic versions of Refresh Optive Advanced available. The average price of Refresh Optive Advanced is about $19.16 per 10, 0.5-1-0.5% solution (quantity in ml)s. To save on this price you can use a Refresh Optive Advanced coupon from SingleCare and pay as little as $12.46 for 10, 0.5-1-0.5% solution (quantity in ml)s. Our coupons are accepted at any participating pharmacy in the United States.
Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.
These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.
Refresh Optive Advanced is a scientifically advanced eye lubricant that is used to treat dry eye symptoms. This brand-name drug is available for purchase with a prescription or as an over-the-counter medication. Currently, there are no generic versions of Refresh Optive Advanced available. The average price of Refresh Optive Advanced is about $19.16 per 10, 0.5-1-0.5% solution (quantity in ml)s. To save on this price you can use a Refresh Optive Advanced coupon from SingleCare and pay as little as $12.46 for 10, 0.5-1-0.5% solution (quantity in ml)s. Our coupons are accepted at any participating pharmacy in the United States.
If you don't have insurance, you could pay about $19.16 for 10, 0.5-1-0.5% solution (quantity in ml)s for Refresh Optive Advanced. With a SingleCare Refresh Optive Advanced coupon, you can save significantly on the price of Refresh Optive Advanced. With our coupon card, your Refresh Optive Advanced price could be as little as $12.46 for 10, 0.5-1-0.5% solution (quantity in ml)s at any participating pharmacies.
The cost of Refresh Optive Advanced with insurance can vary based on your insurance plan and whether it covers this product. Your pharmacist can help you to calculate your copay for Refresh Optive Advanced. With a SingleCare discount card you could pay the reduced price of $12.46 for 10, 0.5-1-0.5% solution (quantity in ml)s for Refresh Optive Advanced during checkout at your local pharmacy.
Medicare does not currently cover Refresh Optive Advanced. You can save on your out-of-pocket costs for Refresh Optive Advanced with a SingleCare savings card. With our savings card, you pay just $12.46 for 10, 0.5-1-0.5% solution (quantity in ml)s on your next purchase of Refresh Optive Advanced. You can redeem your savings at checkout at any participating pharmacy.
Refresh Optive Advanced is a brand-name eye lubricant. Currently, there is not a generic version of Refresh Optive Advanced available.
Refresh Optive Advanced is an eye lubricant that is clinically proven to relieve dry, burning, irritated eyes that are caused by dry eye. Refresh Optive Advanced has a scientifically advanced triple-action relief formula that works on three layers of your tear film. Refresh Optive Advanced is also available in a preservative-free formula.
If you are looking for other dry-eye relief products from Allergan, you could ask your healthcare provider about Refresh products such as Refresh Plus, Refresh Optive Gel drops, and Refresh Optive Mega-3. These products are specially formulated to not only relieve dry eye but help with the production of your natural tears and help to reduce tear evaporation. Refresh Optive Omega-3 is also conveniently packaged in single-use dispensers.
Do not use Refresh Optive Advanced if you are allergic to any part of Refresh Optive Advanced. If the Refresh Optive Advanced solution is cloudy or changes color do not use it. Do not use Refresh Optive Advanced if it is passed its expiration date.
Before you use Refresh Optive Advanced inform your healthcare provider about any other health conditions you may have including if you are pregnant, if you plan on becoming pregnant, and if you are breastfeeding. You should also tell your doctor all the treatments you are using including prescription drugs, over-the-counter medicines, vitamins, and herbal supplements. Providing your doctor with a list of your conditions and medications could minimize your risk of adverse effects and drug interactions.
You should only use Refresh Optive Advanced as recommended by your eye doctor or according to the directions on the packaging.
Refresh Optive Advanced is for external use only. Do not get Refresh Optive Advanced in your mouth. If you do get Refresh Optive Advanced in your mouth, you should call your doctor or poison control right away.
Refresh Optive Advanced may not be safe to use with your contact lenses. Check with your eye care professional to ensure it is safe to use. To avoid contamination, do not touch the tip of the container to any surface. Keep Refresh Optive Advanced and all other medications out of the reach of children and pets.
If you have eye pain, changes in vision, and irritation of the eye, stop using Refresh Optive Advanced and call your healthcare provider right away.
If you have signs of an allergic reaction stop using Refresh Optive Advanced and get immediate medical attention. Symptoms of an allergic reaction include rash, itching, hives, red, swollen, peeling, and blistering skin, chest or throat tightness, difficulty breathing, and swelling of your face, lips, throat, and tongue.
You can get other side effects as this is not a complete list. Talk to your eye doctor about all the risks associated with using Refresh Optive Advanced to ensure this product is right for you.
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SingleCare is a prescription discount service that offers free coupons on thousands of prescription drugs. It can be used whether you have insurance, Medicare, Medicaid, or none of the above, but it cannot be combined with insurance.
SingleCare provides transparent drug pricing, so you can compare discounts at pharmacies near you. Browse singlecare.com to find drug discounts, helpful information about your prescription, and resources to help you make informed health decisions.
Prescription savings vary by prescription and by pharmacy, and may reach up to 80% off cash price. This is a medical discount plan. This is NOT insurance. This program offers you the opportunity to locate providers of various types of medical services who will offer their services to you at discounted rates. The range of discounts for medical or ancillary services provided under the plan will vary depending on the type of provider and service received. You are fully responsible for paying for all health care services but will be entitled to receive a discount from those health care providers in accordance with the specific pre-negotiated discounted fee schedule. This program does not guarantee the quality of the services or procedures offered by the providers. Except for prescription drugs which you will pay directly to the pharmacy at the time of purchase, all other services received through a program provider will be charged to the credit card on file in your member account. The charge will include an administrative fee for use of the program. Towers Administrators LLC is the licensed discount medical plan organization with its administrative office located at 4510 Cox Road, Suite 111, Glen Allen, VA 23060. SingleCare Services, LLC is the marketer of the discount medical plan organization including its website, singlecare.com, with its corporate office located at 99 High Street, Suite 2800, Boston, MA 02110. For additional information, including an up-to-date list of providers, or assistance with any issue related to program membership, please contact member support any time at www.singlecare.com, or by calling toll-free 844-234-3057, 24 hours, 7 days a week (except major holidays). Pharmacy names, logos, brands, and other trademarks are the property of their respective owners.
Blog articles are not medical advice. They are intended for general informational purposes and are not meant to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. If you think you may have a medical emergency, immediately call your physician or dial 911.
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© 2026 SingleCare Administrators. All rights reserved