Systane Ultra Coupons & Prices

Systane Ultra is a brand of eye drop used to relieve dry and irritated eyes. It works to keep eyes lubricated and moist, helping to protect from injury and infection and decreasing symptoms of dry eyes such as itching, burning, and feeling as if something is in your eye. The average price of Systane Ultra is usually around $24.25 for 15, 0.4-0.3% solution (quantity in ml)s. Save money on your prescription and reduce your refill cost to $8.90 by using a SingleCare Systane Ultra coupon at participating pharmacies such as Harris Teeter, Walgreens, Duane Reade, and more.

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Systane Ultra coupon at Costco Pharmacy
$11.90
$ 8.90
$3 off with signupwith signup

Show this free card to your pharmacist.

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Systane Ultra coupon at Kroger Pharmacy
$12.02
$ 9.02
$3 off with signupwith signup

Save an extra $3 on any eligible prescription! Sign up for free

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Systane Ultra coupon at Harris Teeter Pharmacy
$12.02
$ 9.02
$3 off with signupwith signup
Systane Ultra coupon at Food Lion Pharmacy
$ 11.86
Systane Ultra coupon at Walgreens Pharmacy
$23.84
$ 20.84
$3 off with signupwith signup

About SingleCare Pricing

SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.

Any SingleCare bonus savings, including the $3 signup bonus, may only be used once.

Prices updated: 12/05/2025

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About Systane Ultra

Systane Ultra is a brand of eye drop used to relieve dry and irritated eyes. It works to keep eyes lubricated and moist, helping to protect from injury and infection and decreasing symptoms of dry eyes such as itching, burning, and feeling as if something is in your eye. The average price of Systane Ultra is usually around $24.25 for 15, 0.4-0.3% solution (quantity in ml)s. Save money on your prescription and reduce your refill cost to $8.90 by using a SingleCare Systane Ultra coupon at participating pharmacies such as Harris Teeter, Walgreens, Duane Reade, and more.

Systane Ultra Price History & Information

Price History for Systane Ultra

15 count, solution (quantity in ml), 0.4-0.3%

Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.

Average 1-Month Prices for Systane Ultra

15 count, solution (quantity in ml), 0.4-0.3%
PharmacySystane Ultra Retail PriceSystane Ultra SingleCare Price
Walgreens$21.37$19.72
Kroger Pharmacy$17.55$17.55

These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.

About Systane Ultra

Systane Ultra is a brand of eye drop used to relieve dry and irritated eyes. It works to keep eyes lubricated and moist, helping to protect from injury and infection and decreasing symptoms of dry eyes such as itching, burning, and feeling as if something is in your eye. The average price of Systane Ultra is usually around $24.25 for 15, 0.4-0.3% solution (quantity in ml)s. Save money on your prescription and reduce your refill cost to $8.90 by using a SingleCare Systane Ultra coupon at participating pharmacies such as Harris Teeter, Walgreens, Duane Reade, and more.

Systane Ultra FAQs

How much does Systane Ultra cost without insurance?

If you do not have health insurance coverage, the cost of Systane Ultra can be around $24.25 for 15, 0.4-0.3% solution (quantity in ml)s of Systane Ultra. With the ever-increasing price of medications on the market, it is safe to say that everyone is interested in saving money. You can do so by using a SingleCare savings card and paying as low as $8.90 for your Systane Ultra refill.

How much does Systane Ultra cost with insurance?

Health insurance companies generally cover prescription medications only. Therefore, the cost of your Systane Ultra medication might not be covered by insurance unless your doctor writes a prescription for it. Contact your health insurance provider to find out how much Systane Ultra costs under its coverage.

SingleCare can help you to save on your medication by paying $8.90 for Systane Ultra. This may even work out cheaper than with your insurance. Check with your participating pharmacies, such as CVS Pharmacy, Target, Longs Drugs, or Walmart, to compare prices and see how you can save the most on this and any prescription drugs you may be using.

Does Medicare cover Systane Ultra and how much does it cost?

As an over-the-counter medicine, Systane Ultra is not often covered by Medicare. Luckily, you can still save money on this medication. Just use SingleCare's discount card and pay as little as $8.90 for your Systane Ultra medication. Check with your local pharmacist to learn more about savings for Systane Ultra and other medications that you are currently using.

Is there a generic of Systane Ultra?

Systane Ultra is a brand-name medication for which there is no generic version.

What is Systane Ultra?

Systane Ultra is a brand-name lubricant eye drop used to relieve dry, irritated eyes. Dry eyes can be caused by wind, sun, heating or air conditioning, reading or computer use, and certain medications. Systane Ultra helps to lubricate your eyes and keep them moist. It also helps to protect your eyes from infection and injury and decreases the symptoms of dry eyes, such as burning and itching. Systane Ultra is available as a lubricant eye gel as well.

Systane Ultra lubricant eye drops are usually used as often as needed, sometimes one to two times per day. You should always wash your hands before using Systane Ultra. Ensure that the medication dropper does not touch your eye when you are applying these drops. If you are wearing contact lenses, you should remove them before using Systane Ultra or any kind of eye lubricant.

What are the side effects of Systane Ultra?

Systane Ultra is an over-the-counter (OTC) personal care product meant to assist with dry eye relief, however, some unwanted side effects may also occur. Some of these may include temporarily blurred vision and minor burning or stinging when first used. Tell your doctor or pharmacist immediately if any of these side effects persist or worsen.

Serious allergic reactions are often rare but you should seek immediate medical attention if you start to experience symptoms of an allergic reaction such as itching, swelling, rashes, trouble breathing, and severe dizziness.

This is not a complete list of side effects so be sure to check with your healthcare provider before using Systane Ultra to learn about all the benefits and risks associated with treatment.

Where are Systane Ultra coupons from SingleCare accepted?

SingleCare is accepted at most national pharmacies and grocers, including the following:

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