Relistor Coupons & Prices

Relistor (methylnaltrexone bromide) is an FDA approved brand-name drug that is used to treat constipation caused by opioid use. This drug works by blocking the effect of opioids on the gut—without blocking the effect on pain. At the moment, Relistor is not commercially available in its generic form. The average retail price of Relistor is around $192.89 for 1, 0.6ml of 12mg/0.6ml vial. You can use a SingleCare Relistor coupon to save on this total and pay just $184.64 for 1, 0.6ml of 12mg/0.6ml vial at participating pharmacies.

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Relistor  coupon at Kroger Pharmacy
$187.64
$ 184.64
$3 off with signupwith signup

Show this free card to your pharmacist.

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Relistor  coupon at Harris Teeter Pharmacy
$187.64
$ 184.64
$3 off with signupwith signup

Save an extra $3 on any eligible prescription! Sign up for free

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and it's free to join

Relistor  coupon at Costco Pharmacy
$202.21
$ 199.21
$3 off with signupwith signup
Relistor  coupon at Publix Pharmacy
$202.97
$ 199.97
$3 off with signupwith signup
Relistor  coupon at Walgreens Pharmacy
$204.52
$ 201.52
$3 off with signupwith signup
Relistor  coupon at CVS Pharmacy
$213.23
$ 210.23
$3 off with signupwith signup

About SingleCare Pricing

SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.

Any SingleCare bonus savings, including the $3 signup bonus, may only be used once.

Prices updated: 12/08/2025

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About Relistor

Relistor (methylnaltrexone bromide) is an FDA approved brand-name drug that is used to treat constipation caused by opioid use. This drug works by blocking the effect of opioids on the gut—without blocking the effect on pain. At the moment, Relistor is not commercially available in its generic form. The average retail price of Relistor is around $192.89 for 1, 0.6ml of 12mg/0.6ml vial. You can use a SingleCare Relistor coupon to save on this total and pay just $184.64 for 1, 0.6ml of 12mg/0.6ml vial at participating pharmacies.

About Relistor

Relistor (methylnaltrexone bromide) is an FDA approved brand-name drug that is used to treat constipation caused by opioid use. This drug works by blocking the effect of opioids on the gut—without blocking the effect on pain. At the moment, Relistor is not commercially available in its generic form. The average retail price of Relistor is around $192.89 for 1, 0.6ml of 12mg/0.6ml vial. You can use a SingleCare Relistor coupon to save on this total and pay just $184.64 for 1, 0.6ml of 12mg/0.6ml vial at participating pharmacies.

Relistor FAQs

Medically reviewed by Karen BergerPharm.D.
Licensed Pharmacist

How much does Relistor cost without insurance?

The average pricing of Relistor without insurance is around $192.89 for 1, 0.6ml of 12mg/0.6ml vial or sometimes more. You can fill your Relistor prescription for only $184.64 for 1, 0.6ml of 12mg/0.6ml vial when you use a SingleCare Relistor coupon. This money-saving offer can be redeemed at quite a few local drugstores.

How much does Relistor cost with insurance?

You'll have to check with your pharmacist or healthcare provider to calculate your copay with insurance coverage, as costs vary by healthcare plan. Using a SingleCare Relistor savings card can also help you to save money by paying just $184.64 for 1, 0.6ml of 12mg/0.6ml vial for your Relistor prescription.

Does Medicare cover Relistor and how much does it cost?

Relistor is currently covered by some Medicare prescription plans. The average copay ranges from about $439–$1993. SingleCare can help you reduce your Relistor price when you use a Relistor discount card. Just present your card to participating pharmacies and pay as little as $184.64 for 1, 0.6ml of 12mg/0.6ml vial for your Relistor prescription fill or refill.

Is there a generic of Relistor ?

Relistor is only available as a brand-name drug; there is no generic version currently available.

What is Relistor ?

Relistor is a prescription drug that reduces constipation that is caused by using narcotic medicine (opioids) for four weeks or longer. Methylnaltrexone, the main ingredient in Relistor , works by preventing constipation without reducing the pain-relieving effects of the narcotic. Relistor is also administered to adults who use narcotic medicine to treat severe chronic pain that is not caused by cancer. If you stop taking the opioid medication that is causing constipation, you can also stop taking Relistor . Relistor is usually used after laxatives have been tried without success.

Relistor is available in two primary forms; tablets and injections. The injection form of this drug can be used in adults who have advanced illness or pain caused by cancer and are receiving palliative care.

If you have a bowel blockage or a history of bowel blockage, then you should not use this drug. Tell your healthcare provider if you have kidney or liver problems. 

Tell your doctor if you are pregnant or breastfeeding, or plan to become pregnant, as this drug can cause opioid withdrawal symptoms in your unborn baby or in a baby who is breastfed. 

Also, tell your doctor about all the medications you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

What are the side effects of Relistor ?

Common side effects associated with the use of Relistor may include diarrhea, increased sweating, bloating, dizziness, gas. If you have severe diarrhea, stop taking Relistor and consult your healthcare provider immediately.

Serious allergic reaction to this drug is rare, however, you should be aware of possible signs of an allergic reaction. These may include rash, itching, swelling (especially of the face, tongue, or throat), severe dizziness, and/or trouble breathing. If any of these symptoms occur, seek emergency medical treatment.

This is not a complete list of adverse effects. Talk to your doctor before using Relistor for any additional information and medical advice.

Medically reviewed by Karen BergerPharm.D.
Licensed Pharmacist

After receiving her doctorate from the University of Pittsburgh School of Pharmacy, Karen Berger, Pharm.D., has worked in both chain and independent community pharmacies. She currently works at an independent pharmacy in New Jersey. Dr. Berger enjoys helping patients understand medical conditions and medications—both in person as a pharmacist, and online as a medical writer and reviewer.

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Where are Relistor  coupons from SingleCare accepted?

SingleCare is accepted at most national pharmacies and grocers, including the following:

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