Relistor (methylnaltrexone bromide) is an FDA approved brand-name drug that is used to treat constipation caused by opioid use. This drug works by blocking the effect of opioids on the gut—without blocking the effect on pain. At the moment, Relistor is not commercially available in its generic form. The average retail price of Relistor is around $192.89 for 1, 0.6ml of 12mg/0.6ml vial. You can use a SingleCare Relistor coupon to save on this total and pay just $184.64 for 1, 0.6ml of 12mg/0.6ml vial at participating pharmacies.
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SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.
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Prices updated: 12/08/2025
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Relistor (methylnaltrexone bromide) is an FDA approved brand-name drug that is used to treat constipation caused by opioid use. This drug works by blocking the effect of opioids on the gut—without blocking the effect on pain. At the moment, Relistor is not commercially available in its generic form. The average retail price of Relistor is around $192.89 for 1, 0.6ml of 12mg/0.6ml vial. You can use a SingleCare Relistor coupon to save on this total and pay just $184.64 for 1, 0.6ml of 12mg/0.6ml vial at participating pharmacies.
Relistor (methylnaltrexone bromide) is an FDA approved brand-name drug that is used to treat constipation caused by opioid use. This drug works by blocking the effect of opioids on the gut—without blocking the effect on pain. At the moment, Relistor is not commercially available in its generic form. The average retail price of Relistor is around $192.89 for 1, 0.6ml of 12mg/0.6ml vial. You can use a SingleCare Relistor coupon to save on this total and pay just $184.64 for 1, 0.6ml of 12mg/0.6ml vial at participating pharmacies.
The average pricing of Relistor without insurance is around $192.89 for 1, 0.6ml of 12mg/0.6ml vial or sometimes more. You can fill your Relistor prescription for only $184.64 for 1, 0.6ml of 12mg/0.6ml vial when you use a SingleCare Relistor coupon. This money-saving offer can be redeemed at quite a few local drugstores.
You'll have to check with your pharmacist or healthcare provider to calculate your copay with insurance coverage, as costs vary by healthcare plan. Using a SingleCare Relistor savings card can also help you to save money by paying just $184.64 for 1, 0.6ml of 12mg/0.6ml vial for your Relistor prescription.
Relistor is currently covered by some Medicare prescription plans. The average copay ranges from about $439–$1993. SingleCare can help you reduce your Relistor price when you use a Relistor discount card. Just present your card to participating pharmacies and pay as little as $184.64 for 1, 0.6ml of 12mg/0.6ml vial for your Relistor prescription fill or refill.
Relistor is only available as a brand-name drug; there is no generic version currently available.
Relistor is a prescription drug that reduces constipation that is caused by using narcotic medicine (opioids) for four weeks or longer. Methylnaltrexone, the main ingredient in Relistor , works by preventing constipation without reducing the pain-relieving effects of the narcotic. Relistor is also administered to adults who use narcotic medicine to treat severe chronic pain that is not caused by cancer. If you stop taking the opioid medication that is causing constipation, you can also stop taking Relistor . Relistor is usually used after laxatives have been tried without success.
Relistor is available in two primary forms; tablets and injections. The injection form of this drug can be used in adults who have advanced illness or pain caused by cancer and are receiving palliative care.
If you have a bowel blockage or a history of bowel blockage, then you should not use this drug. Tell your healthcare provider if you have kidney or liver problems.
Tell your doctor if you are pregnant or breastfeeding, or plan to become pregnant, as this drug can cause opioid withdrawal symptoms in your unborn baby or in a baby who is breastfed.
Also, tell your doctor about all the medications you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.
Common side effects associated with the use of Relistor may include diarrhea, increased sweating, bloating, dizziness, gas. If you have severe diarrhea, stop taking Relistor and consult your healthcare provider immediately.
Serious allergic reaction to this drug is rare, however, you should be aware of possible signs of an allergic reaction. These may include rash, itching, swelling (especially of the face, tongue, or throat), severe dizziness, and/or trouble breathing. If any of these symptoms occur, seek emergency medical treatment.
This is not a complete list of adverse effects. Talk to your doctor before using Relistor for any additional information and medical advice.
After receiving her doctorate from the University of Pittsburgh School of Pharmacy, Karen Berger, Pharm.D., has worked in both chain and independent community pharmacies. She currently works at an independent pharmacy in New Jersey. Dr. Berger enjoys helping patients understand medical conditions and medications—both in person as a pharmacist, and online as a medical writer and reviewer.
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Prescription savings vary by prescription and by pharmacy, and may reach up to 80% off cash price. This is a medical discount plan. This is NOT insurance. This program offers you the opportunity to locate providers of various types of medical services who will offer their services to you at discounted rates. The range of discounts for medical or ancillary services provided under the plan will vary depending on the type of provider and service received. You are fully responsible for paying for all health care services but will be entitled to receive a discount from those health care providers in accordance with the specific pre-negotiated discounted fee schedule. This program does not guarantee the quality of the services or procedures offered by the providers. Except for prescription drugs which you will pay directly to the pharmacy at the time of purchase, all other services received through a program provider will be charged to the credit card on file in your member account. The charge will include an administrative fee for use of the program. Towers Administrators LLC is the licensed discount medical plan organization with its administrative office located at 4510 Cox Road, Suite 111, Glen Allen, VA 23060. SingleCare Services, LLC is the marketer of the discount medical plan organization including its website, singlecare.com, with its corporate office located at 99 High Street, Suite 2800, Boston, MA 02110. For additional information, including an up-to-date list of providers, or assistance with any issue related to program membership, please contact member support any time at www.singlecare.com, or by calling toll-free 844-234-3057, 24 hours, 7 days a week (except major holidays). Pharmacy names, logos, brands, and other trademarks are the property of their respective owners.
Blog articles are not medical advice. They are intended for general informational purposes and are not meant to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. If you think you may have a medical emergency, immediately call your physician or dial 911.
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© 2025 SingleCare Administrators. All rights reserved