What is Renflexis: Uses, Warnings & Interactions

Updated May 14, 2025  •  Published Nov 6, 2021

Renflexis overview

BRAND NAMES:

  • Renflexis, Inflectra, Remicade

Generic Names:

  • Renflexis

Uses:

  • Treats rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, Crohn disease, plaque psoriasis, and ulcerative colitis.

Therapeutic Classes:

  • Immunological Agent, Gastrointestinal Agent

Forms:

  • Injectable

How it’s taken:

  • By injection

What is Renflexis used for?

What form(s) does Renflexis come in

  • Injectable

What are common Renflexis doses?

  • Solution Reconstituted 100MG

Common Renflexis prescriptions

  • Renflexis
    100mg solution reconstituted

How to take Renflexis

  • This medicine should come with a Medication Guide. Ask your pharmacist for a copy if you do not have one.

  • Injection routeA nurse or other health provider will give you this medicine.

  • Injection routeYour doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein. This medicine must be given slowly, so the needle will have to stay in place for at least 2 hours.

  • Injection routeYour doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein. This medicine must be given slowly, so the needle will have to remain in place for at least 2 hours.

  • Your doctor may also give you other medicines (including allergy medicine, fever medicine, steroid medicine) before or during your infusion.

What to do if you miss a dose of Renflexis

Renflexis contraindications

  • This medicine is not right for everyone. You should not receive it if you had an allergic reaction to infliximab products or murine (mouse) proteins, or if you have moderate to severe heart failure.

  • This medicine is not right for everyone. You should not receive it if you had an allergic reaction to infliximab or murine (mouse) proteins or if you have moderate to severe heart failure.

Renflexis warnings

  • This medicine increases your risk of infection, which could result in serious or life-threatening illness. Tell your doctor if you have a history of frequent or serious infections, including tuberculosis or hepatitis B. Make sure your doctor knows if you have cuts or sores in your body, an infection, or already have trouble with your immune system. This risk may be higher in people who are older than 65 years or have diabetes. Avoid sick people, and wash your hands often.

  • Tell your doctor if you are pregnant or breastfeeding, or if you have liver disease, heart disease, COPD, a bleeding disorder, blood or bone marrow problems, or cancer. Tell your doctor if you have a history of seizures, multiple sclerosis, Guillain-Barré syndrome, or a similar nervous system disease.

  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

  • This medicine may cause the following problems:Increased risk of cancer (including lymphoma, cervical or skin cancer)Liver problemsNew or worsening heart failureInfusion reactions, including heart attack, stroke, low or high blood pressure, heart rhythm problems, or eye or vision problems during or after the infusionLupus-like syndrome

  • This medicine may make you bleed, bruise, or get infections more easily. Take precautions to prevent illness and injury. Wash your hands often.

  • Unusual bleeding, bruising, tiredness, or weakness

  • Warm, red, swollen, or painful skin, blisters, skin sores

  • This medicine may cause the following problems:Increased risk for infections, which may be life-threateningIncreased risk of certain cancers (including lymphoma, skin cancer, cervical cancer)Liver problemsInfusion reaction (including heart attack, stroke, changes in blood pressure, or heart rhythm problems)

  • You will need to have a skin test for tuberculosis (TB) before you start receiving this medicine. Tell your doctor if you or anyone in your home has ever had a positive TB skin test or been exposed to TB.

  • Tell your doctor if you are pregnant or breastfeeding, or if you have liver disease, heart disease, COPD, a bleeding disorder, blood or bone marrow problems, cancer, diabetes, or any type of infection. Tell your doctor if you have a history of seizures, multiple sclerosis, Guillain-Barré syndrome or a similar nervous system disease, or frequent or serious infections (including tuberculosis or hepatitis B). Tell your doctor if you have recently received or are scheduled to receive a vaccine.

  • Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.

  • Seizures, numbness, tingling, problems with vision, speech, or walking

Renflexis interactions

  • You should not receive a vaccine without your doctor's approval. A live virus vaccine could cause an infection. Children should be current on all vaccines before they start treatment with this medicine. If you received infliximab-abda while pregnant, tell the baby's doctor.

  • Some medicines may affect how infliximab-abda works. Tell your doctor if you are using any of the following:Abatacept, anakinra, cyclosporine, etanercept, theophylline, tocilizumabBlood thinner (including warfarin)Medicine that weakens the immune system (including methotrexate, steroid)

  • Tell your doctor if you have had light treatment for psoriasis.

  • Some medicines may affect how infliximab works. Tell your doctor if you are using any of the following:Abatacept, anakinra, cyclosporine, etanercept, theophylline, tocilizumabBlood thinner (including warfarin)Medicine that weakens the immune system (including ciprofloxacin, methotrexate, metronidazole, aminosalicylates, steroids)

  • Tell your doctor if you have had light treatment (phototherapy) for psoriasis.

  • This medicine may interfere with vaccines. Ask your doctor before you get a flu shot or any other vaccines.

  • Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.

Renflexis side effects

Serious Side Effects

  • Blistering, peeling, red skin rash

  • Fast, pounding, or uneven heartbeat

  • Lightheadedness, dizziness, or fainting

  • Fever, chills, cough, runny or stuffy nose, sore throat, body aches

  • Warm, red, swollen, or painful skin, blisters, skin sores

  • Chest pain, coughing up blood, trouble breathing

  • Numbness or weakness in your arm or leg, or on one side of your body

  • Seizures, numbness, tingling, problems with vision, speech, or walking

  • Sudden or severe headache

  • Unusual bleeding, bruising, tiredness, or weakness

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Dark urine or pale stools, nausea, vomiting, loss of appetite, stomach pain, yellow skin or eyes

  • Joint or muscle pain or swelling, trouble swallowing, rash on the cheeks or arms that gets worse in the sun

  • Seizures, numbness or tingling of the skin, problems with vision, speech, or walking

  • Joint or muscle pain, swelling, trouble swallowing

  • Change in how much or how often you urinate, pain while urinating

  • Headache, lightheadedness, trouble breathing

Less Serious Side Effects

  • Redness, pain, or swelling where the needle is placed

  • Diarrhea, heartburn

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