Rezdiffra Coupons & Prices

Rezdiffra FAQs

How much does Rezdiffra cost without insurance?

Without insurance, Rezdiffra costs $5,222.4 per 30, 100mg tablets on average.

People without insurance can use a SingleCare coupon for Rezdiffra to save up to 80%. Currently, our lowest price for Rezdiffra is $4,027.35 per 30, 100mg tablets.

How much does Rezdiffra cost with insurance?

The cost of Rezdiffra with insurance will depend on your particular health insurance plan, whether it covers Rezdiffra, what tier Rezdiffra is placed on in your plan’s formulary, and whether you’ve met your plan’s deductible. You can contact your insurance plan for the most recent pricing information for this medication.

How to save on Rezdiffra

You can save money on Rezdiffra with a free prescription discount card from SingleCare. Using a SingleCare card can reduce your Rezdiffra costs to $4,027.35 for 30, 100mg tablets.

The manufacturer of Rezdiffra also has a copay savings program. To be eligible, you must reside in the U.S. and have commercial insurance that does not cover the full cost of your prescription. This program is not available to people on federally funded prescription plans, including Medicare, Medicaid, or Veterans Affairs. You can contact the manufacturer, Madrigal Pharmaceuticals, for more information and eligibility requirements.

Is there a generic of Rezdiffra?

Rezdiffra was approved by the U.S. Food and Drug Administration (FDA) in March of 2024, so it is available as a brand-name drug only. There is no generic version of Rezdiffra for sale yet.

What is Rezdiffra?

Rezdiffra is a prescription drug approved by the FDA to treat adults with NASH with moderate to advanced liver fibrosis (or scarring). Rezdiffra is intended to be used in combination with diet and exercise.

Noncirrhotic nonalcoholic steatohepatitis (NASH) is a severe form of non-alcoholic fatty liver disease, which involves a buildup of fat in the liver that causes inflammation and damage and can lead to liver scarring. NASH is not caused by alcohol use.

The FDA granted accelerated approval for Rezdiffra. The FDA’s Accelerated Approval Program allows for earlier approval of medications that may be used to treat serious conditions. Continued approval for this use may be contingent on the results of ongoing clinical trials. 

Rezdiffra is not indicated to treat cirrhosis of the liver. It is also not approved for people younger than 18 years old.

The active ingredient in Rezdiffra is called resmetirom. It is a thyroid hormone receptor-beta agonist.

What are the side effects of Rezdiffra?

The most common side effects of Rezdiffra (reported in at least 5% of people) are diarrhea, nausea, vomiting, constipation, abdominal pain, itching, and dizziness.

Serious side effects of Rezdiffra may include liver injury (hepatotoxicity) and gallbladder problems.

Tell your healthcare provider about all medical conditions you have and medications you take before using Rezdiffra. Certain medications, such as gemfibrozil or cyclosporine, should not be taken with Rezdiffra. If you take a statin for high cholesterol, such as Lipitor (atorvastatin), Crestor (rosuvastatin), Pravachol (pravastatin), or Zocor (simvastatin), your doctor may need to adjust your statin dosage when taking Rezdiffra. If you take Plavix (clopidogrel), your doctor will need to lower your dose of Rezdiffra. 

It is not known whether Rezdiffra is safe or effective in people younger than 18 years old or pregnant or breastfeeding women.

What doses of Rezdiffra are available?

Rezdiffra dosage is based on body weight. 

• The recommended dose of Rezdiffra for people weighing less than 100 kg (220 pounds) is 80 mg by mouth once per day.

• The recommended dose of Rezdiffra for people weighing 100 kg (220 pounds) or more is 100 mg by mouth once per day.

Rezdiffra is an oral tablet that can be taken with or without food.