Rifaximin is a prescription drug approved by the FDA for the treatment of traveler's diarrhea. This medication can also be used to treat irritable bowel syndrome (IBS) and hepatic encephalopathy. There is no generic version of Rifaximin available on the market. Your Rifaximin prescription can be quite expensive with an average retail price of $491.76. Use a SingleCare Rifaximin coupon at any local CVS, Target, Longs Drugs, Walmart, Kroger, Fry's, Harris Teeter, Walgreens or Duane Reade to save significantly. Dosage can affect Rifaximin prices. SingleCare’s lowest price for Rifaximin is currently $451.88 for 0.12, 500gm of bottle.
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Prices updated: 09/23/2026
Rifaximin is a prescription drug approved by the FDA for the treatment of traveler's diarrhea. This medication can also be used to treat irritable bowel syndrome (IBS) and hepatic encephalopathy. There is no generic version of Rifaximin available on the market. Your Rifaximin prescription can be quite expensive with an average retail price of $491.76. Use a SingleCare Rifaximin coupon at any local CVS, Target, Longs Drugs, Walmart, Kroger, Fry's, Harris Teeter, Walgreens or Duane Reade to save significantly. Dosage can affect Rifaximin prices. SingleCare’s lowest price for Rifaximin is currently $451.88 for 0.12, 500gm of bottle.
Rifaximin is a prescription drug approved by the FDA for the treatment of traveler's diarrhea. This medication can also be used to treat irritable bowel syndrome (IBS) and hepatic encephalopathy. There is no generic version of Rifaximin available on the market. Your Rifaximin prescription can be quite expensive with an average retail price of $491.76. Use a SingleCare Rifaximin coupon at any local CVS, Target, Longs Drugs, Walmart, Kroger, Fry's, Harris Teeter, Walgreens or Duane Reade to save significantly. Dosage can affect Rifaximin prices. SingleCare’s lowest price for Rifaximin is currently $451.88 for 0.12, 500gm of bottle.
Rifaximin is quite expensive without insurance coverage, costing around $491.76. Customers who use a SingleCare Rifaximin coupon can pay as low as $451.88 for their prescription. Use your free SingleCare coupon for your prescription at pharmacies near you such as Target, Kroger, and Fry's.
The average copay for Rifaximin can vary depending on your type of health insurance plan and level of coverage. However, using a SingleCare discount card could save you significantly on your next prescription. Pay as low as $451.88 at pharmacies near you such as Walmart, Walgreens, and Longs Drugs.
Rifaximin is often covered by your Medicare Part D and Medicare Advantage plans. The average Medicare copay can still be expensive with a range of about $95-$2724. However, using a SingleCare savings card could save you more than Medicare insurance. Ask your pharmacist at your local pharmacy to compare prices at checkout so that you can get the lowest price possible.
Xifaxan is the brand name of Rifaximin.
Rifaximin (Xifaxan) is a generic prescription drug approved by the FDA in the treatment of diarrhea. This tablet can also be used to treat irritable bowel syndrome and hepatic encephalopathy. Hepatic encephalopathy is a brain disorder caused by a buildup of toxins in the brain due to liver disease. Rifaximin is an antibiotic that works against bacteria such as E. coli that cause diarrhea. This medication is meant for persons older than 12.
Always remember to read the instruction leaflet and to consult your healthcare provider about medical advice concerning the correct dosage and frequency for your medical condition. Rifaximin is meant to be taken 3 times a day for the treatment of diarrhea and irritable bowel syndrome. It is meant to be taken 2 times a day for the treatment of hepatic encephalopathy. The greatest effect is achieved when taken evenly apart. Rifaximin should not be shared even with persons experiencing the same conditions. Skipping doses and changing length or frequency of treatment can increase the risk of infection by a resistant bacterial strain.
It is important to remember to consult your doctor on what medications and foods should be taken when using Rifaximin in order to avoid side effects. The most common side effects include flatulence, headache, and nausea. Consult your doctor for medical advice on how to treat side effects, especially if they persist or get worse.
Severe allergic reactions to Rifaximin are not common. However, immediately contact your healthcare professional should you experience stomach cramps, blood, or mucus in your stool or fainting. This is not a full list of possible side effects. Seek medical advice before using Rifaximin to determine if this drug is right for you.
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SingleCare is a prescription discount service that offers free coupons on thousands of prescription drugs. It can be used whether you have insurance, Medicare, Medicaid, or none of the above, but it cannot be combined with insurance.
SingleCare provides transparent drug pricing, so you can compare discounts at pharmacies near you. Browse singlecare.com to find drug discounts, helpful information about your prescription, and resources to help you make informed health decisions.
Prescription savings vary by prescription and by pharmacy, and may reach up to 80% off cash price. This is a medical discount plan. This is NOT insurance. This program offers you the opportunity to locate providers of various types of medical services who will offer their services to you at discounted rates. The range of discounts for medical or ancillary services provided under the plan will vary depending on the type of provider and service received. You are fully responsible for paying for all health care services but will be entitled to receive a discount from those health care providers in accordance with the specific pre-negotiated discounted fee schedule. This program does not guarantee the quality of the services or procedures offered by the providers. Except for prescription drugs which you will pay directly to the pharmacy at the time of purchase, all other services received through a program provider will be charged to the credit card on file in your member account. The charge will include an administrative fee for use of the program. Towers Administrators LLC is the licensed discount medical plan organization with its administrative office located at 4510 Cox Road, Suite 111, Glen Allen, VA 23060. SingleCare Services, LLC is the marketer of the discount medical plan organization including its website, singlecare.com, with its corporate office located at 99 High Street, Suite 2800, Boston, MA 02110. For additional information, including an up-to-date list of providers, or assistance with any issue related to program membership, please contact member support any time at www.singlecare.com, or by calling toll-free 844-234-3057, 24 hours, 7 days a week (except major holidays). Pharmacy names, logos, brands, and other trademarks are the property of their respective owners.
Blog articles are not medical advice. They are intended for general informational purposes and are not meant to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. If you think you may have a medical emergency, immediately call your physician or dial 911.
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© 2026 SingleCare Administrators. All rights reserved