What is Ropivacaine: Uses, Warnings & Interactions

Updated May 14, 2025  •  Published Dec 30, 2020

Ropivacaine overview

BRAND NAMES:

  • Naropin, Naropin Novaplus, PremierPro Rx Naropin

Generic Names:

  • Ropivacaine Hcl

Uses:

  • Numbs an area of your body before, during, or after surgery or childbirth. Also used to relieve acute pain. This medicine is a local anesthetic.

Therapeutic Classes:

  • Anesthetic, Local

Forms:

  • Injectable

How it’s taken:

  • By injection

What is Ropivacaine used for?

What form(s) does Ropivacaine come in

  • Injectable

What are common Ropivacaine doses?

  • Vial 10ML of 2MG/ML

  • Vial 20ML of 2MG/ML

  • Vial 30ML of 5MG/ML

Common Ropivacaine prescriptions

  • ROPivacaine HCl
    100ml of 2mg/ml bottle

  • ROPivacaine HCl
    100ml of 2mg/ml flex cont

  • ROPivacaine HCl
    200ml of 2mg/ml flex cont

  • ROPivacaine HCl
    10ml of 10mg/ml vial

  • ROPivacaine HCl
    10ml of 2mg/ml vial

  • ROPivacaine HCl
    20ml of 10mg/ml vial

  • ROPivacaine HCl
    20ml of 2mg/ml vial

  • ROPivacaine HCl
    20ml of 5mg/ml vial

  • ROPivacaine HCl
    20ml of 7.5mg/ml vial

  • ROPivacaine HCl
    30ml of 5mg/ml vial

How to take Ropivacaine

  • A nurse or other trained health professional will give you this medicine. It is given through a needle placed into one of your veins, into your upper arm, into the head and neck area, or into the space around the spinal nerves in your lower back.

  • A nurse or other trained health professional will give you this medicine. It is given through a needle placed into one of your veins, into your upper arm, into the head and neck area, or into the space around the spinal nerves in your lower back.

What to do if you miss a dose of Ropivacaine

Ropivacaine contraindications

  • This medicine is not right for everyone. You should not be given this receive it if you had an allergic reaction to ropivacaine or similar medicines.

Ropivacaine warnings

  • Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, heart problems, blood vessel disease, heart rhythm problems, low blood pressure, lung or breathing problems, a blood disorder, or G6PD.

  • This medicine may cause methemoglobinemia (blood disorder).

  • You may experience temporary loss of sensation and movement, usually in the lower half of your body, if you receive this medicine into your lower back (epidural).

  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

Ropivacaine interactions

  • Some medicines can affect how ropivacaine works. Tell your doctor if you are using any of the following:Acetaminophen, amiodarone, chloroquine, fluvoxamine, imipramine, metoclopramide, primaquine, quinine, sulfasalazine, theophyllineBlood pressure medicineCancer medicine (including cyclophosphamide, flutamide, hydroxyurea, ifosfamide, rasburicase)Medicine to treat an infection (including dapsone, ketoconazole, nitrofurantoin, para-aminosalicylic acid, sulfonamide)Medicine to treat seizures (including phenobarbital, phenytoin, sodium valproate)Nitrate or nitrite medicine (including nitric oxide, nitroglycerin, nitroprusside, nitrous oxide)

  • This medicine may make you dizzy. Avoid driving, using machines, or doing anything else that could be dangerous if you are not alert.

Ropivacaine side effects

Serious Side Effects

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Lightheadedness, nervousness, restlessness, blurred or double vision, twitching

  • Pale, gray, or blue lips, nails, or skin, dark urine, headache, unusual tiredness or weakness

  • Ringing in the ears, seizures

  • Uneven, pounding, or fast heartbeat

  • Headache, lightheadedness, or fainting.

  • Itchy skin (in children).

  • Nausea, or vomiting.

  • Numbness or tingling in your hands, feet, legs, or other body parts.

  • Unusually slow or fast heart beat.

Less Serious Side Effects

  • Headache, lightheadedness, or fainting.

  • Feeling unusually uptight or nervous.

  • Decrease in how much or how often you urinate.

  • Numbness or tingling in your hands, feet, legs, or other body parts.

  • Nausea, or vomiting.

  • Fever, or a feeling of getting the chills.

  • Itchy skin (in children).

  • Feeling unusually weak in your muscles.

  • Unusually slow or fast heart beat.

  • Pain, itching, burning, swelling, or a lump under your skin where the needle is placed

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