Epinephrine Hcl is a generic medication used as an emergency treatment for anaphylaxis, a potentially life-threatening allergic reaction with symptoms such as hives, swelling of the lips or tongue, low blood pressure, and trouble breathing. It can be used to treat severe allergic reactions to insect stings or bites, foods, and other allergens. The average retail price of Epinephrine Hcl is around $744.41 for 2, 0.3mg/0.3ml solution auto-injectors. SingleCare may help you lower this total to $169.03 with an Epinephrine Hcl coupon. This coupon can be redeemed at participating pharmacies.
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SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.
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Prices updated: 12/05/2025
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Epinephrine Hcl is a generic medication used as an emergency treatment for anaphylaxis, a potentially life-threatening allergic reaction with symptoms such as hives, swelling of the lips or tongue, low blood pressure, and trouble breathing. It can be used to treat severe allergic reactions to insect stings or bites, foods, and other allergens. The average retail price of Epinephrine Hcl is around $744.41 for 2, 0.3mg/0.3ml solution auto-injectors. SingleCare may help you lower this total to $169.03 with an Epinephrine Hcl coupon. This coupon can be redeemed at participating pharmacies.
Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.
| Pharmacy | Epipen 2-Pak Retail Price | Epinephrine Retail Price | Epinephrine SingleCare Price |
|---|---|---|---|
| CVS Pharmacy | - | $196.80 | $135.34 |
| Walmart | - | $328.18 | $220.09 |
| Walgreens | $735.10 | $275.79 | $170.55 |
| Kroger Pharmacy | $730.48 | $508.56 | $382.73 |
| Albertsons Pharmacy | - | $602.00 | $375.28 |
These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.
Epinephrine Hcl is a generic medication used as an emergency treatment for anaphylaxis, a potentially life-threatening allergic reaction with symptoms such as hives, swelling of the lips or tongue, low blood pressure, and trouble breathing. It can be used to treat severe allergic reactions to insect stings or bites, foods, and other allergens. The average retail price of Epinephrine Hcl is around $744.41 for 2, 0.3mg/0.3ml solution auto-injectors. SingleCare may help you lower this total to $169.03 with an Epinephrine Hcl coupon. This coupon can be redeemed at participating pharmacies.
The average cost of Epinephrine Hcl without health insurance may be around $744.41 or more. You could purchase 2, 0.3mg/0.3ml solution auto-injectors of Epinephrine Hcl for only $169.03 when you use a SingleCare Epinephrine Hcl discount card. These automatic savings can be redeemed at a number of popular drugstores near you.
Every insurance plan is different, so you'll have to call your insurance company or pharmacist to calculate the exact price of Epinephrine Hcl with your insurance coverage. Still, the price with insurance could actually be higher than the cash price of Epinephrine Hcl. That's why it's important for customers to always ask the pharmacist to compare the retail price of a drug to their copay with insurance.
Pharmacy coupons from SingleCare can be applied to the cash price of Epinephrine Hcl and other prescription drugs. In some cases, a SingleCare discount could be greater than what you'd save with insurance. For instance, you could pay a reduced price of $169.03 for 2, 0.3mg/0.3ml solution auto-injectors when you use a SingleCare savings card for your Epinephrine Hcl refills.
Epinephrine Hcl is sometimes covered by Medicare Part D and Medicare Advantage plans. Patients who cannot access Medicare coverage for this drug may have to pay as much as $744.41. You can lower this total and save on your out-of-pocket costs by using a SingleCare savings card at participating pharmacies. A SingleCare card may allow you to pay a discounted price of $169.03 for 2, 0.3mg/0.3ml solution auto-injectors.
Epinephrine Hcl is a generic version of the medication. Brand-name versions of Epinephrine Hcl include Auvi-Q, EpiPen 2-Pak, and AdrenaClick. Search any of these drug names on SingleCare's website or app to access coupons.
Epinephrine Hcl is an FDA-approved generic medication used to treat low blood pressure, trouble breathing, hives, severe skin itching, and other symptoms of a severe allergic reaction known as anaphylaxis. It is especially used to treat severe allergic reactions to insect stings or bites, foods, and other allergens.
Epinephrine Hcl works by narrowing blood vessels and opening airways in the lungs. Epinephrine Hcl may also be used to treat exercise-induced anaphylaxis or low blood pressure caused by septic shock.
This medication comes in the form of an injectable solution and is usually administered with an auto-injector pen. The Epinephrine Hcl auto-injectors may be kept on-hand to be self-injected by a person with a history of severe allergic reactions. You should seek emergency treatment after using Epinephrine Hcl to treat severe allergic reactions. This medication does not replace the need for professional medical care, and further treatment may be required in some cases.
Epinephrine Hcl is typically injected into the skin or the muscle of your outer thigh. The auto-injector used to apply this medication is a disposable single-use system and therefore should not be re-used for subsequent events. Follow the instructions provided on the medication guides that come with Epinephrine Hcl, or check with your doctor for additional information on how to use this medication.
Some unwanted side effects resulting from the use of Epinephrine Hcl may include irritation or redness at the injection site, restlessness, tremors, dizziness, nausea, a fast heartbeat, and a sensation of coldness on the skin. Inform your doctor or pharmacist about any effects you may be experiencing after using this medication, especially if they persist or worsen.
This is not a complete list of adverse effects. Other effects not listed here may also occur while you are taking this medication. Check with your healthcare provider for complete medical advice on the risks and benefits involved with using Epinephrine Hcl.
Gerardo Sison, Pharm.D., graduated from the University of Florida. He has worked in both community and hospital settings, providing drug information and medication therapy management services. As a medical writer, he hopes to educate and empower patients to better manage their health and navigate their treatment plans.
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Prescription savings vary by prescription and by pharmacy, and may reach up to 80% off cash price. This is a medical discount plan. This is NOT insurance. This program offers you the opportunity to locate providers of various types of medical services who will offer their services to you at discounted rates. The range of discounts for medical or ancillary services provided under the plan will vary depending on the type of provider and service received. You are fully responsible for paying for all health care services but will be entitled to receive a discount from those health care providers in accordance with the specific pre-negotiated discounted fee schedule. This program does not guarantee the quality of the services or procedures offered by the providers. Except for prescription drugs which you will pay directly to the pharmacy at the time of purchase, all other services received through a program provider will be charged to the credit card on file in your member account. The charge will include an administrative fee for use of the program. Towers Administrators LLC is the licensed discount medical plan organization with its administrative office located at 4510 Cox Road, Suite 111, Glen Allen, VA 23060. SingleCare Services, LLC is the marketer of the discount medical plan organization including its website, singlecare.com, with its corporate office located at 99 High Street, Suite 2800, Boston, MA 02110. For additional information, including an up-to-date list of providers, or assistance with any issue related to program membership, please contact member support any time at www.singlecare.com, or by calling toll-free 844-234-3057, 24 hours, 7 days a week (except major holidays). Pharmacy names, logos, brands, and other trademarks are the property of their respective owners.
Blog articles are not medical advice. They are intended for general informational purposes and are not meant to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. If you think you may have a medical emergency, immediately call your physician or dial 911.
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© 2025 SingleCare Administrators. All rights reserved