What is Rubraca: Uses, Warnings & Interactions

Updated May 14, 2025  •  Published Dec 30, 2020

Rubraca overview

BRAND NAMES:

  • Rubraca

Generic Names:

  • Rubraca

Uses:

  • Treats cancer, including ovarian, fallopian tube, primary peritoneal, or prostate cancer.

Therapeutic Classes:

  • Antineoplastic Agent

Forms:

  • Tablet

How it’s taken:

  • By mouth

What is Rubraca used for?

Rubraca is a cancer medication used to treat patients with ovarian cancer. It works to block the affected cancer cells from multiplying and spreading.

What form(s) does Rubraca come in

  • Tablet

What are common Rubraca doses?

  • Tablet 300MG

Common Rubraca prescriptions

  • Rubraca
    200mg tablet

  • Rubraca
    250mg tablet

  • Rubraca
    300mg tablet

How to take Rubraca

  • Missed dose: If you miss a dose of this medicine, skip the missed dose and go back to your regular dosing schedule. Do not double doses. If you vomit after taking a dose, do not take an extra dose.

  • Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.

  • Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.

  • Your doctor may also give you other medicines (including gonadotropin-releasing hormone medicine) during prostate cancer treatment or you should have had surgical removal of the testes before using this medicine.

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

  • Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

  • Your doctor may also give you other medicines (including gonadotropin-releasing hormone medicine) during prostate cancer treatment or you should have had surgical removal of the testes before using this medicine.

  • Missed dose: If you miss a dose of this medicine, skip the missed dose and go back to your regular dosing schedule. Do not double doses. If you vomit after taking a dose, do not take an extra dose.

  • Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.

What to do if you miss a dose of Rubraca

Rubraca contraindications

  • This medicine is not right for everyone. Do not use it if you had an allergic reaction to rucaparib, or if you are pregnant or breastfeeding.

Rubraca warnings

  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

  • This medicine may increase your risk for bone marrow problems, including myelodysplastic syndrome or acute myeloid leukemia.

  • Do not breastfeed during treatment and for at least 2 weeks after the last dose.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

  • Oral routeMedicines used to treat cancer are very strong and can have many side effects. Before receiving this medicine, make sure you understand all the risks and benefits. It is important for you to work closely with your doctor during your treatment.

  • Oral routeIt is not safe to take this medicine during pregnancy. It could harm an unborn baby. Tell your doctor right away if you become pregnant. Pregnancy tests are required before treatment with this medicine. Use an effective form of birth control during treatment and for at least 6 months after your last dose. Male patients with female partners should use an effective form of birth control during treatment and for at least 3 months after the last dose.

  • Tell your doctor if you have kidney disease, liver disease, or blood or bone marrow problems.

  • This medicine may make your skin more sensitive to sunlight. Wear sunscreen. Do not use sunlamps or tanning beds.

  • Do not donate sperm while you are using this medicine and for at least 3 months after your last dose.

Rubraca interactions

  • Some foods and medicines can affect how rucaparib works. Tell your doctor if you are using caffeine, digoxin, midazolam, omeprazole, or warfarin.

Rubraca side effects

Serious Side Effects

  • Chest pain, trouble breathing

  • Fever, chills, cough, runny or stuffy nose, sore throat, body aches

  • Unusual bleeding, bruising, or weakness

  • Blood in the urine or stools

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

Less Serious Side Effects

  • Tiredness

  • Sores or white patches on your lips, mouth, or throat

  • Constipation, diarrhea, nausea, vomiting, stomach pain or upset

  • Skin rash

  • Change in taste, decreased appetite

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