Sulfamethoxazole Coupons & Prices

Sulfamethoxazole is a generic prescription antibiotic that treats or prevents a range of bacterial infections, including urinary tract infections, meningitis, middle ear infections, food poisoning, E. coli infections, and eye infections. Sulfamethoxazole is also used to support other drugs in fighting malaria or toxoplasmosis. Neither generic Sulfamethoxazole nor its brand-name version, Gantanol, are available in the United States. Sulfamethoxazole combined with trimethoprim (Bactrim), however, is one of the most-prescribed antibiotic drugs. Sulfamethoxazole is no longer available in the United States.

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0.69 bottle500gm of Edit

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Sulfamethoxazole coupon at Kroger Pharmacy
$55.81
$ 52.81
$3 off with signupwith signup

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Sulfamethoxazole coupon at Harris Teeter Pharmacy
$55.81
$ 52.81
$3 off with signupwith signup

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Sulfamethoxazole coupon at Walgreens Pharmacy
$59.43
$ 56.43
$3 off with signupwith signup
Sulfamethoxazole coupon at Walmart Neighborhood Market Pharmacy
$60.06
$ 57.06
$3 off with signupwith signup
Sulfamethoxazole coupon at Walmart Pharmacy
$60.06
$ 57.06
$3 off with signupwith signup
Sulfamethoxazole coupon at Publix Pharmacy
$61.61
$ 58.61
$3 off with signupwith signup
$ 60.99
$ 64.70
$76.94
$ 73.94
$3 off with signupwith signup

About SingleCare Pricing

SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.

Any SingleCare bonus savings, including the $3 signup bonus, may only be used once.

Prices updated: 02/04/2026

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4.8 average rating
About Sulfamethoxazole

Sulfamethoxazole is a generic prescription antibiotic that treats or prevents a range of bacterial infections, including urinary tract infections, meningitis, middle ear infections, food poisoning, E. coli infections, and eye infections. Sulfamethoxazole is also used to support other drugs in fighting malaria or toxoplasmosis. Neither generic Sulfamethoxazole nor its brand-name version, Gantanol, are available in the United States. Sulfamethoxazole combined with trimethoprim (Bactrim), however, is one of the most-prescribed antibiotic drugs. Sulfamethoxazole is no longer available in the United States.

About Sulfamethoxazole

Sulfamethoxazole is a generic prescription antibiotic that treats or prevents a range of bacterial infections, including urinary tract infections, meningitis, middle ear infections, food poisoning, E. coli infections, and eye infections. Sulfamethoxazole is also used to support other drugs in fighting malaria or toxoplasmosis. Neither generic Sulfamethoxazole nor its brand-name version, Gantanol, are available in the United States. Sulfamethoxazole combined with trimethoprim (Bactrim), however, is one of the most-prescribed antibiotic drugs. Sulfamethoxazole is no longer available in the United States.

Sulfamethoxazole FAQs

How much does Sulfamethoxazole cost without insurance?

The quantity and dosage of Sulfamethoxazole will vary depending on the nature of the bacterial infection, so the retail cost of a Sulfamethoxazole prescription will vary. Patients can expect to pay $64.69 for Sulfamethoxazole at full price.

$52.81 is all you pay for the same prescription with a SingleCare Sulfamethoxazole coupon. From generics to brand name prescription drugs, you can save as much as 80% with a SingleCare savings card.

Sulfamethoxazole is not prescribed or available at pharmacies in the United States except in combination with other drugs, like trimethoprim.

How much does Sulfamethoxazole cost with insurance?

The amount of your Sulfamethoxazole copay depends on the quantity and dosage prescribed as well as your insurance plan. With SingleCare, Sulfamethoxazole costs as little as $52.81 for 0.69, 500gm of bottle, which may be lower than your insurance copay. Consult with your pharmacist to determine the best value.

Sulfamethoxazole is not prescribed or available at pharmacies in the United States except in combination with other drugs, like trimethoprim.

Does Medicare cover Sulfamethoxazole and how much does it cost?

Sulfamethoxazole is not covered by Medicare Part D and Medicare Advantage. Sulfamethoxazole is not prescribed or available at pharmacies in the United States except in combination with other drugs, like trimethoprim.

What is the brand name of Sulfamethoxazole?

Sulfamethoxazole is a generic prescription drug available in countries other than the United States. The brand-name version was Gantanol, but Roche has discontinued its production. Sulfamethoxazole combined with trimethoprim is one of the most-prescribed antibiotic prescription drugs at this time; it is available as a brand-name prescription drug, Bactrim, from Roche, as well as several generic alternatives.

What is Sulfamethoxazole?

Sulfamethoxazole is a generic antibiotic that stops the growth of bacterial infections. Sulfamethoxazole belongs to a class of wide-spectrum antibiotics called sulfa drugs that prevent bacteria from making folate (vitamin B9). Without folate, bacteria cannot make DNA and are unable to replicate.

Sulfamethoxazole treats or prevents a range of bacterial infections, including urinary tract infections, meningitis, middle ear infections, food poisoning (listeria), E. coli infections, and eye infections (conjunctivitis). Sulfamethoxazole is also used to support other drugs in fighting malaria or toxoplasmosis.

Neither generic Sulfamethoxazole nor its brand-name version, Gantanol, are available in the United States. Sulfamethoxazole combined with trimethoprim (Bactrim), however, is one of the most-prescribed antibiotic drugs.

What are the side effects of Sulfamethoxazole?

The most common side effects of Sulfamethoxazole are stomach upset, nausea, diarrhea, lightheadedness, and dizziness. Serious side effects can be severe: lowered red and white blood cell counts, hepatitis (swelling in the liver), convulsions, hallucinations, and depression. Allergic reactions are common and can be potentially severe. They include hives, itching, and rash. The most severe allergic reactions are epidermal necrolysis (blistering and cell death of the skin throughout the body) and Stevens-Johnson syndrome (a severe skin reaction throughout the body). The combination of Stevens-Johnson syndrome and epidermal necrolysis has a 50% fatality rate. Consult a physician immediately if you experience a Sulfamethoxazole allergic reaction.

This is not a complete list of side effects that may occur. Ask your doctor or pharmacist about possible side effects before taking this medicine.

Where are Sulfamethoxazole coupons from SingleCare accepted?

SingleCare is accepted at most national pharmacies and grocers, including the following:

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