Symtuza is a combination prescription drug that is used to treat the Human Immunodeficiency Virus- 1 (HIV-1) in adults. It contains darunavir, cobicistat, emtricitabine, and tenofovir alafenamide. There is no generic version of Symtuza available at the moment. Without insurance or Medicare, you could pay as much as $5,751.6 for your Symtuza prescription. You can reduce the cost of Symtuza to just $4,578.05 by using a SingleCare Symtuza coupon with your purchase.
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SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.
Any SingleCare bonus savings, including the $3 signup bonus, may only be used once.
Prices updated: 12/05/2025
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Symtuza is a combination prescription drug that is used to treat the Human Immunodeficiency Virus- 1 (HIV-1) in adults. It contains darunavir, cobicistat, emtricitabine, and tenofovir alafenamide. There is no generic version of Symtuza available at the moment. Without insurance or Medicare, you could pay as much as $5,751.6 for your Symtuza prescription. You can reduce the cost of Symtuza to just $4,578.05 by using a SingleCare Symtuza coupon with your purchase.
Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.
| Pharmacy | Symtuza Retail Price | Symtuza SingleCare Price |
|---|---|---|
| CVS Pharmacy | $5550.90 | $4775.10 |
| Walgreens | $5421.60 | $4997.70 |
| Kroger Pharmacy | $5511.60 | $4600.50 |
These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.
Symtuza is a combination prescription drug that is used to treat the Human Immunodeficiency Virus- 1 (HIV-1) in adults. It contains darunavir, cobicistat, emtricitabine, and tenofovir alafenamide. There is no generic version of Symtuza available at the moment. Without insurance or Medicare, you could pay as much as $5,751.6 for your Symtuza prescription. You can reduce the cost of Symtuza to just $4,578.05 by using a SingleCare Symtuza coupon with your purchase.
If you don't have insurance, you could pay as much as $5,751.6 out-of-pocket for your Symtuza prescription refill. You can reduce your out-of-pocket costs and stop overpaying for your Symtuza refills by using a SingleCare prescription discount card. With our Symtuza discount card, you pay only $4,578.05 for Symtuza. You can redeem your instant savings at your local CVS Pharmacy.
The average cost of Symtuza with insurance tends to vary based on the type of health insurance plan you have. You can speak to your insurance provider to find out the exact amount Symtuza would cost you as well as how much you would have to copay on your prescription. With a SingleCare Symtuza coupon, you can reduce the cash price of Symtuza and pay our lowest price of $4,578.05. Our free coupons are accepted at any participating Walmart or Walgreens in the United States.
Medicare Part D and Advantage plans do offer coverage for Symtuza. If you are still looking for a way to save on the retail price of Symtuza, you could use SingleCare's free Symtuza coupons. With a SingleCare prescription savings card, you could save as much as 80% on your prescription drugs. With our Symtuza savings card you pay only $4,578.05 for Symtuza at your local pharmacy.
Symtuza is a brand-name antiretroviral medicine that is manufactured by Janssen Therapeutics. There is no generic version of Symtuza available as yet. Prezcobix and Prezista are similar medications also manufactured by Janssen Therapeutics.
Symtuza is a combination prescription drug that is used to treat the human immunodeficiency virus- 1 (HIV-1) in adults. This antiretroviral medicine contains darunavir, cobicistat, emtricitabine, and tenofovir alafenamide. HIV is a disease that causes acquired immune deficiency syndrome (AIDS).
Do not use Symtuza if you are allergic to any of its ingredients (cobicistat/emtricitabine/tenofovir alafenamide, and darunavir). If you are pregnant do not use Symtuza. If you are taking any medications that contain lurasidone, pimozide, alfuzosin, carbamazepine, dihydroergotamine, dronedarone, ivabradine, ranolazine, colchicine, elbasvir or grazoprevir, do not take Symtuza.
Before taking Symtuza tell your healthcare provider about any other medical conditions you may have including Hepatitis B or C, diabetes, kidney problems, or hemophilia, you need to tell your doctor. If you become pregnant while using Symtuza tell your doctor right away. You should not breastfeed if you have HIV-1 as you could infect your baby.
You also need to tell your doctor about all the treatments you are using including all prescription medicines, over-the-counter medicines, vitamins, and herbal supplements. If you are using certain cholesterol-lowering medications like lovastatin, simvastatin, sedatives like midazolam, or triazolam, seizure medications such as carbamazepine, phenytoin, or phenobarbital, opioids, ritonavir, ranolazine, rifampin, sildenafil, or St. John's wort, you need to tell your doctor.
Use Symtuza exactly as it was prescribed by your healthcare provider. Symtuza is usually taken once daily with food. You may need to do liver function tests while using Symtuza and for several months after your last dose. In case of a missed dose, you should get medical advice from your healthcare professional. Do not have unprotected sex or share razors or toothbrushes.
Common side effects of Symtuza include gas, rash, diarrhea, nausea and vomiting, rash, headache, and changes in the shape and location of your body fat.
Symtuza could also cause serious side effects like swelling in your neck (enlarged thyroid), little or no urination, lactic acidosis, unusual muscle pain, trouble breathing, stomach pain, loss of appetite, dark urine, clay-colored stools, and yellowing of the skin or eyes. If you have any of these symptoms call your doctor right away.
If you have signs of an allergic reaction after taking Symtuza get immediate medical attention. Symptoms of an allergic reaction include rash, hives, trouble breathing, and swelling of your face, lips, throat, and tongue.
For a full list of the risks associated with using Symtuza, you can talk to your doctor. You may also report any side effects to the FDA.
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Prescription savings vary by prescription and by pharmacy, and may reach up to 80% off cash price. This is a medical discount plan. This is NOT insurance. This program offers you the opportunity to locate providers of various types of medical services who will offer their services to you at discounted rates. The range of discounts for medical or ancillary services provided under the plan will vary depending on the type of provider and service received. You are fully responsible for paying for all health care services but will be entitled to receive a discount from those health care providers in accordance with the specific pre-negotiated discounted fee schedule. This program does not guarantee the quality of the services or procedures offered by the providers. Except for prescription drugs which you will pay directly to the pharmacy at the time of purchase, all other services received through a program provider will be charged to the credit card on file in your member account. The charge will include an administrative fee for use of the program. Towers Administrators LLC is the licensed discount medical plan organization with its administrative office located at 4510 Cox Road, Suite 111, Glen Allen, VA 23060. SingleCare Services, LLC is the marketer of the discount medical plan organization including its website, singlecare.com, with its corporate office located at 99 High Street, Suite 2800, Boston, MA 02110. For additional information, including an up-to-date list of providers, or assistance with any issue related to program membership, please contact member support any time at www.singlecare.com, or by calling toll-free 844-234-3057, 24 hours, 7 days a week (except major holidays). Pharmacy names, logos, brands, and other trademarks are the property of their respective owners.
Blog articles are not medical advice. They are intended for general informational purposes and are not meant to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. If you think you may have a medical emergency, immediately call your physician or dial 911.
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© 2025 SingleCare Administrators. All rights reserved