What is Torsemide: Uses, Warnings & Interactions
Torsemide is a generic diuretic that reduces fluids and salt in the body. Because it’s a very potent diuretic, healthcare providers use it for serious fluid buildup (edema) due to heart failure, cirrhosis, and kidney disease. It can also treat high blood pressure but is not a doctor’s first choice. Doses are administered as tablets, which are taken once daily. Torsemide can cause serious side effects, the most common of which are electrolyte depletion and low blood pressure.
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Torsemide overview
BRAND NAMES:
Soaanz
Generic Names:
Torsemide
Uses:
Treats fluid retention (edema) caused by heart failure, kidney disease, or liver disease. Also treats high blood pressure.
Therapeutic Classes:
Diuretic, loop diuretics
Forms:
Tablet
How it’s taken:
By mouth
What is Torsemide used for?
Torsemide is a loop diuretic used to reduce fluid buildup (edema) in people with heart failure, kidney disease, or liver cirrhosis. It’s also FDA-approved to reduce blood pressure in people diagnosed with hypertension.
What form(s) does Torsemide come in
Tablet
5 mg
10 mg
20 mg
60 mg
100 mg
What are common Torsemide doses?
For edema due to heart failure: 10–200 mg taken once daily
For edema due to chronic kidney failure: 20–200 mg taken once daily
For edema due to liver cirrhosis: 10–40 mg taken once daily
For ascites (abdominal swelling) and edema due to liver cirrhosis: 5–10 mg taken once daily
Common Torsemide prescriptions
Torsemide
100mg tabletTorsemide
10mg tabletTorsemide
20mg tabletTorsemide
5mg tablet
How to take Torsemide
Take your medicine as directed. The dose may need to be changed several times.
Carefully follow the prescriber’s instructions about any special diet.
Torsemide tablets can be taken with or without food.
Swallow the tablets with a drink of water.
Store the medicine in a light-resistant container at room temperature.
What to do if you miss a dose of Torsemide
Take a dose as soon as you remember.
If it is almost time for the next dose, wait and take the next dose as scheduled.
Do not take an extra dose to make up for a missed dose.
Torsemide contraindications
This medicine is not safe for everyone.
It is too hazardous for people who are:
Not urinating (anuria)
In a coma due to liver failure
Are allergic to torsemide
Torsemide warnings
Tell any doctor or other healthcare provider who treats you that you are using this medicine. Torsemide may need to be stopped before surgical or other procedures.
The prescriber will need follow-up visits and blood tests to monitor your treatment. Keep all appointments.
Call the prescribing clinician if your symptoms do not improve or if they get worse.
Before starting torsemide, tell the prescriber if you are pregnant, breastfeeding, or have:
Kidney disease
Liver disease
Heart disease
Low fluids (dehydration)
Electrolyte problems
Diabetes
Gout
Hearing problems
If you are on a low-salt diet, the prescriber needs to know this, or the medicine may be unsafe to take.
Torsemide can cause serious problems, including:
Electrolyte depletion, particularly low sodium or low potassium
Dangerously low blood pressure
Worsening kidney function
Ear damage and hearing loss
Dehydration
Heart rhythm abnormalities
Diabetes
This medicine may make you dizzy, drowsy, or lightheaded. Do not drive or do anything else that could be dangerous until you know how this medicine affects you.
If you faint or pass out while on torsemide, stop taking the medication and immediately contact the prescribing healthcare provider.
Torsemide interactions
To avoid potentially hazardous drug interactions, tell the prescribing healthcare provider about all prescription drugs, over-the-counter medications, and supplements you use before taking torsemide.
Tell other healthcare providers you are using this medicine before they prescribe new medications or before they perform X-rays or CT scans using contrast agents.
Some medicines may cause problems when combined with torsemide. Tell your doctor if you are also taking:
NSAIDs such as aspirin or ibuprofen
Blood pressure medications, particularly ACE inhibitors or angiotensin receptor blockers (ARBs)
Other diuretics
Amiodarone, cisplatin, digoxin, ethacrynic acid, fluconazole, lithium, miconazole, oxandrolone, phenytoin, probenecid, rifampin, or warfarin
If you are taking cholestyramine, take it several hours before or several hours after taking a dose of torsemide.
Torsemide side effects
Serious side effects
Talk to a doctor if you notice any signs or symptoms of a possible serious side effect, including:
Chest pain, fast or uneven heartbeat
Lightheadedness, dizziness, fainting
Confusion, weakness, muscle twitching
Dry mouth, increased thirst, muscle cramps, problems urinating, nausea, or vomiting
Hearing problems, hearing loss, ringing in the ears
Sudden and severe stomach pain, nausea, vomiting, fever, lightheadedness
Blistering, peeling, red or dark skin rash
Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
Less serious side effects
Urinating more than usual
Unusual tiredness or weakness
Sources:
Demadex drug summary, Prescriber’s Digital Reference (PDR)
Soaanz torsemide tablet prescribing information, DailyMed (NIH National Library of Medicine)
Torsemide, StatPearls
Torsemide tablet prescribing information, DailyMed (NIH National Library of Medicine)
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