Trimethoprim is an FDA-approved generic prescription antibiotic used to treat bacterial infections. It belongs to a class of drugs called antifolate antibiotics. Trimethoprim may be prescribed to treat bacterial infections like urinary tract infections. The retail price of Trimethoprim is $88.66 for 30, 100mg tablets, but it may cost $4.90 for 30, 100mg tablets with SingleCare's Trimethoprim coupon.
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SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.
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Prices updated: 12/05/2025
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Trimethoprim is an FDA-approved generic prescription antibiotic used to treat bacterial infections. It belongs to a class of drugs called antifolate antibiotics. Trimethoprim may be prescribed to treat bacterial infections like urinary tract infections. The retail price of Trimethoprim is $88.66 for 30, 100mg tablets, but it may cost $4.90 for 30, 100mg tablets with SingleCare's Trimethoprim coupon.
Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.
| Pharmacy | Trimethoprim Retail Price | Trimethoprim SingleCare Price |
|---|---|---|
| CVS Pharmacy | $27.00 | $27.00 |
| Walmart | $69.90 | $69.30 |
| Walgreens | $72.10 | $36.00 |
| Kroger Pharmacy | $57.90 | $57.90 |
These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.
Trimethoprim is an FDA-approved generic prescription antibiotic used to treat bacterial infections. It belongs to a class of drugs called antifolate antibiotics. Trimethoprim may be prescribed to treat bacterial infections like urinary tract infections. The retail price of Trimethoprim is $88.66 for 30, 100mg tablets, but it may cost $4.90 for 30, 100mg tablets with SingleCare's Trimethoprim coupon.
The cash price of a Trimethoprim prescription will vary depending on the quantity and dosage prescribed. On average, patients without insurance pay $88.66 for 30, 100mg tablets.
With a SingleCare Trimethoprim coupon, you could pay $4.90 per 30, 100mg tablets is all you pay for the same prescription. You can save as much as 80% with a SingleCare prescription discount card.
The amount of your Trimethoprim copay depends on the quantity and dosage prescribed as well as your insurance plan’s coverage. With SingleCare, Trimethoprim may cost $4.90 for 30, 100mg tablets, which may be lower than your insurance copay. Contact your insurance provider for your potential Trimethoprim copay. You can also ask your pharmacist to help you compare your copay cost for Trimethoprim with your SingleCare savings price.
Trimethoprim is usually covered under Medicare prescription drug plans. The exact cost of Trimethoprim with Medicare can vary. If you do not have Medicare coverage, you can try using a SingleCare Trimethoprim coupon to potentially reduce the cost to $4.90 for 30, 100mg tablets.
Trimethoprim is a generic prescription drug that is widely available. Brand names of Trimethoprim include Primsol, Proloprim, and Trimpex. Brand-name versions of Trimethoprim may be discontinued and unavailable at this time.
Trimethoprim is a generic antibiotic used to treat bacterial infections, including urinary tract infections. It may also be used to treat a certain type of pneumonia and traveler’s diarrhea. Trimethoprim belongs to a class of antibiotics that kills bacteria by disrupting their use of folic acid, a substance vital for bacterial growth.
Trimethoprim is only used to treat bacterial infections. It is ineffective against viral or fungal infections. Quantity and dosage will depend on the type and severity of the infection.
Take this medication as prescribed by a healthcare provider. Tell your healthcare provider about any medical conditions you have and other medications you may be taking before starting treatment with Trimethoprim.
The most common side effects of Trimethoprim are diarrhea, nausea, vomiting, headache, and an upset stomach. Serious side effects include changes in blood cell counts and allergic reactions.
Trimethoprim allergies are uncommon but potentially severe. Allergic reactions may include hives, rash, itching, swelling, and difficulty breathing. The most serious allergic reactions, which are rare, can result in anaphylactic shock (a dangerous and potentially fatal drop in blood pressure). Get emergency medical help immediately if you experience an allergic reaction to Trimethoprim.
This is not a complete list of side effects. Consult your doctor or healthcare professional for additional information and medical advice regarding other possible side effects or drug interactions. You can report negative side effects to the FDA.
Gerardo Sison, Pharm.D., graduated from the University of Florida. He has worked in both community and hospital settings, providing drug information and medication therapy management services. As a medical writer, he hopes to educate and empower patients to better manage their health and navigate their treatment plans.
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Prescription savings vary by prescription and by pharmacy, and may reach up to 80% off cash price. This is a medical discount plan. This is NOT insurance. This program offers you the opportunity to locate providers of various types of medical services who will offer their services to you at discounted rates. The range of discounts for medical or ancillary services provided under the plan will vary depending on the type of provider and service received. You are fully responsible for paying for all health care services but will be entitled to receive a discount from those health care providers in accordance with the specific pre-negotiated discounted fee schedule. This program does not guarantee the quality of the services or procedures offered by the providers. Except for prescription drugs which you will pay directly to the pharmacy at the time of purchase, all other services received through a program provider will be charged to the credit card on file in your member account. The charge will include an administrative fee for use of the program. Towers Administrators LLC is the licensed discount medical plan organization with its administrative office located at 4510 Cox Road, Suite 111, Glen Allen, VA 23060. SingleCare Services, LLC is the marketer of the discount medical plan organization including its website, singlecare.com, with its corporate office located at 99 High Street, Suite 2800, Boston, MA 02110. For additional information, including an up-to-date list of providers, or assistance with any issue related to program membership, please contact member support any time at www.singlecare.com, or by calling toll-free 844-234-3057, 24 hours, 7 days a week (except major holidays). Pharmacy names, logos, brands, and other trademarks are the property of their respective owners.
Blog articles are not medical advice. They are intended for general informational purposes and are not meant to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. If you think you may have a medical emergency, immediately call your physician or dial 911.
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© 2025 SingleCare Administrators. All rights reserved