Twyneo Coupons & Prices

Twyneo is a Acne Combinations class prescription created by Mayne Pharma. The typical cash price of Twyneo is $1,318.89 per 1, 30gm of 0.1-3% pump btl, but you can pay only $931.10 for 1, 30gm of 0.1-3% pump btl of Twyneo when you use a SingleCare drug coupon.

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1 pump btl30gm of 0.1-3%Edit

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You have 0.00 in available bonus savings. Bonus savings will be automatically applied to your next eligible prescription fill.

Twyneo coupon at Kroger Pharmacy
$934.10
$ 931.10
$3 off with signupwith signup

Show this free card to your pharmacist.

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Twyneo coupon at Harris Teeter Pharmacy
$934.10
$ 931.10
$3 off with signupwith signup

Save an extra $3 on any eligible prescription! Sign up for free

Members can save even more
and it's free to join

Twyneo coupon at Food Lion Pharmacy
$ 977.00
Twyneo coupon at CVS Pharmacy
$986.64
$ 983.64
$3 off with signupwith signup
Twyneo coupon at Publix Pharmacy
$999.80
$ 996.80
$3 off with signupwith signup
Twyneo coupon at Walmart Neighborhood Market Pharmacy
$1003.01
$ 1,000
$3 off with signupwith signup
$1003.01
$ 1,000
$3 off with signupwith signup
$1008.20
$ 1,005
$3 off with signupwith signup
$1012.80
$ 1,010
$3 off with signupwith signup

About SingleCare Pricing

SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.

Any SingleCare bonus savings, including the $3 signup bonus, may only be used once.

Prices updated: 12/05/2025

Members save the most

Save big on your prescriptions
with the free SingleCare app.
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About Twyneo

Twyneo is a Acne Combinations class prescription created by Mayne Pharma. The typical cash price of Twyneo is $1,318.89 per 1, 30gm of 0.1-3% pump btl, but you can pay only $931.10 for 1, 30gm of 0.1-3% pump btl of Twyneo when you use a SingleCare drug coupon.

Twyneo Price History & Information

Price History for Twyneo

1 count, pump btl, 30gm of 0.1-3%

Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.

Average 1-Month Prices for Twyneo

1 count, pump btl, 30gm of 0.1-3%
PharmacyTwyneo Retail PriceTwyneo SingleCare Price
CVS Pharmacy$582.00$477.60
Walgreens$591.90$523.50
Kroger Pharmacy$590.40$429.60

These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.

About Twyneo

Twyneo is a Acne Combinations class prescription created by Mayne Pharma. The typical cash price of Twyneo is $1,318.89 per 1, 30gm of 0.1-3% pump btl, but you can pay only $931.10 for 1, 30gm of 0.1-3% pump btl of Twyneo when you use a SingleCare drug coupon.

Twyneo FAQs

How much is Twyneo with SingleCare?

Twyneo costs $931.10 for 1, 30gm of 0.1-3% pump btl with a free Twyneo coupon from SingleCare.  But, you could lower this cost more depending on your Rx details. Use the dropdown menu above to update your prescription information (i.e., generic/brand, quantity, dosage, form) to find the most accurate price of Twyneo with SingleCare at a pharmacy near you.

How much does Twyneo cost without insurance?

The average out-of-pocket cost of Twyneo without health insurance is $1,318.89 per 1, 30gm of 0.1-3% pump btl though you can save using a SingleCare Twyneo coupon to pay just $931.10 for 1, 30gm of 0.1-3% pump btl of Twyneo. If you don’t have access to an insurance plan can still use SingleCare for free Twyneo coupons.

How much does Twyneo cost with insurance?

Every individual insurance formulary has different details and may or may not cover Twyneo. The cost of Twyneo with insurance coverage differs according to your plan - verify with your insurance provider for definitive drug coverage and payment information. If your insurance plan does not offer coverage for Twyneo, you can use a SingleCare card to get discounts on Twyneo at your neighborhood pharmacy. Additionally, you can also use SingleCare cards if you have Medicare or Medicaid. When Medicare or Medicaid doesn’t completely cover your Twyneo medication, use SingleCare instead. Go to the SingleCare website or app to compare the lowest price of Twyneo with SingleCare versus your Twyneo copay with insurance or Medicare.

Is generic Twyneo available?

Twyneo is a brand-name drug made by Mayne Pharma. There is no generic variant of Twyneo available at this time.

How to use SingleCare for Twyneo

SingleCare is accepted at most major pharmacies and grocers, such as Walgreens, Kroger, Walmart, CVS, Safeway, and more. You can text, email, print, or save your free Twyneo coupon to your digital wallet and show your pharmacist when you pick up your prescription. 

Where are Twyneo coupons from SingleCare accepted?

SingleCare is accepted at most national pharmacies and grocers, including the following:

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