Twyneo Coupons & Prices

Twyneo is a Acne Combinations class drug made by MAYNE PHARMA. The typical out-of-pocket price for Twyneo is $1,344.85 per 1, 30gm of 0.1-3% pump btl, but you can pay $457.87 for 1, 30gm of 0.1-3% pump btl of Twyneo with your SingleCare discount card.

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1 pump btl30gm of 0.1-3%Edit

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Twyneo coupon at Walgreens Pharmacy
$460.87
$ 457.87
$3 off with signupwith signup

Show this free card to your pharmacist.

This coupon is not insurance.
Twyneo coupon at Kroger Pharmacy
$841.44
$ 838.44
$3 off with signupwith signup
Twyneo coupon at Harris Teeter Pharmacy
$841.44
$ 838.44
$3 off with signupwith signup
Twyneo coupon at CVS Pharmacy
$895.95
$ 892.95
$3 off with signupwith signup
Twyneo coupon at Publix Pharmacy
$898.30
$ 895.30
$3 off with signupwith signup
Twyneo coupon at Walmart Neighborhood Market Pharmacy
$913.77
$ 910.77
$3 off with signupwith signup
$913.77
$ 910.77
$3 off with signupwith signup
$919.24
$ 916.24
$3 off with signupwith signup

About SingleCare Pricing

SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.

Any SingleCare bonus savings, including the $3 signup bonus, may only be used once.

Prices updated: 09/22/2026

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4.8 average rating
About Twyneo

Twyneo is a Acne Combinations class drug made by MAYNE PHARMA. The typical out-of-pocket price for Twyneo is $1,344.85 per 1, 30gm of 0.1-3% pump btl, but you can pay $457.87 for 1, 30gm of 0.1-3% pump btl of Twyneo with your SingleCare discount card.

Twyneo Price History & Information

Price History for Twyneo

1 count, Pump btl, 30gm of 0.1-3%

Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.

Average 1-Month Prices for Twyneo

1 count, Pump btl, 30gm of 0.1-3%
PharmacyTwyneo Retail PriceTwyneo SingleCare Price
CVS Pharmacy$964.44$755.59
Walmart$590.40$465.60
Walgreens$591.90$513.90
Kroger Pharmacy$1140.00$795.00

These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.

About Twyneo

Twyneo is a Acne Combinations class drug made by MAYNE PHARMA. The typical out-of-pocket price for Twyneo is $1,344.85 per 1, 30gm of 0.1-3% pump btl, but you can pay $457.87 for 1, 30gm of 0.1-3% pump btl of Twyneo with your SingleCare discount card.

Twyneo FAQs

How much is Twyneo with SingleCare?

Twyneo costs $457.87 for 1, 30gm of 0.1-3% pump btl with a free Twyneo coupon from SingleCare.  However, you could pay less depending on your prescription information. Use the dropdown menu above to enter your Rx info (i.e., generic/brand, quantity, dosage, form) to get the most accurate prices of Twyneo with SingleCare near you.

How much does Twyneo cost without insurance?

The normal counter cost of Twyneo without health insurance is $1,344.85 per 1, 30gm of 0.1-3% pump btl though you can save money using a SingleCare Twyneo coupon to pay $457.87 for 1, 30gm of 0.1-3% pump btl of Twyneo. People without access to an insurance plan can always use SingleCare for free Twyneo coupons.

How much does Twyneo cost with insurance?

Each specific insurance formulary is distinct and may or may not cover Twyneo. The cost of Twyneo with insurance coverage varies depending on your plan - contact your insurance carrier for specific formulary coverage and copay specifics. If your insurance plan does not include Twyneo, you can use a SingleCare card to save on Twyneo at your participating pharmacy. In addition, you can also use SingleCare savings if you have Medicare or Medicaid. When Medicare or Medicaid doesn’t cover your Twyneo fill, use SingleCare instead. Use the SingleCare website or app to find the lowest cost of Twyneo with SingleCare versus your Twyneo price with insurance or Medicare.

Is generic Twyneo available?

Twyneo is a brand-name medication produced by MAYNE PHARMA. There is no generic form of Twyneo available at this time.

How to use SingleCare for Twyneo

SingleCare is accepted at most major pharmacies and grocers, including Walgreens, Kroger, Walmart, CVS, Safeway, and more. You can text, email, print, or save your free Twyneo coupon to your digital wallet and show your pharmacist at checkout. 

Where are Twyneo coupons from SingleCare accepted?

SingleCare is accepted at most national pharmacies and grocers, including the following:

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