Twyneo is a Acne Combinations class prescription created by Mayne Pharma. The typical cash price of Twyneo is $1,318.89 per 1, 30gm of 0.1-3% pump btl, but you can pay only $931.10 for 1, 30gm of 0.1-3% pump btl of Twyneo when you use a SingleCare drug coupon.
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SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.
Any SingleCare bonus savings, including the $3 signup bonus, may only be used once.
Prices updated: 12/05/2025
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Twyneo is a Acne Combinations class prescription created by Mayne Pharma. The typical cash price of Twyneo is $1,318.89 per 1, 30gm of 0.1-3% pump btl, but you can pay only $931.10 for 1, 30gm of 0.1-3% pump btl of Twyneo when you use a SingleCare drug coupon.
Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.
| Pharmacy | Twyneo Retail Price | Twyneo SingleCare Price |
|---|---|---|
| CVS Pharmacy | $582.00 | $477.60 |
| Walgreens | $591.90 | $523.50 |
| Kroger Pharmacy | $590.40 | $429.60 |
These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.
Twyneo is a Acne Combinations class prescription created by Mayne Pharma. The typical cash price of Twyneo is $1,318.89 per 1, 30gm of 0.1-3% pump btl, but you can pay only $931.10 for 1, 30gm of 0.1-3% pump btl of Twyneo when you use a SingleCare drug coupon.
Twyneo costs $931.10 for 1, 30gm of 0.1-3% pump btl with a free Twyneo coupon from SingleCare. But, you could lower this cost more depending on your Rx details. Use the dropdown menu above to update your prescription information (i.e., generic/brand, quantity, dosage, form) to find the most accurate price of Twyneo with SingleCare at a pharmacy near you.
The average out-of-pocket cost of Twyneo without health insurance is $1,318.89 per 1, 30gm of 0.1-3% pump btl though you can save using a SingleCare Twyneo coupon to pay just $931.10 for 1, 30gm of 0.1-3% pump btl of Twyneo. If you don’t have access to an insurance plan can still use SingleCare for free Twyneo coupons.
Every individual insurance formulary has different details and may or may not cover Twyneo. The cost of Twyneo with insurance coverage differs according to your plan - verify with your insurance provider for definitive drug coverage and payment information. If your insurance plan does not offer coverage for Twyneo, you can use a SingleCare card to get discounts on Twyneo at your neighborhood pharmacy. Additionally, you can also use SingleCare cards if you have Medicare or Medicaid. When Medicare or Medicaid doesn’t completely cover your Twyneo medication, use SingleCare instead. Go to the SingleCare website or app to compare the lowest price of Twyneo with SingleCare versus your Twyneo copay with insurance or Medicare.
Twyneo is a brand-name drug made by Mayne Pharma. There is no generic variant of Twyneo available at this time.
SingleCare is accepted at most major pharmacies and grocers, such as Walgreens, Kroger, Walmart, CVS, Safeway, and more. You can text, email, print, or save your free Twyneo coupon to your digital wallet and show your pharmacist when you pick up your prescription.
SingleCare is accepted at most national pharmacies and grocers, including the following:
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Prescription savings vary by prescription and by pharmacy, and may reach up to 80% off cash price. This is a medical discount plan. This is NOT insurance. This program offers you the opportunity to locate providers of various types of medical services who will offer their services to you at discounted rates. The range of discounts for medical or ancillary services provided under the plan will vary depending on the type of provider and service received. You are fully responsible for paying for all health care services but will be entitled to receive a discount from those health care providers in accordance with the specific pre-negotiated discounted fee schedule. This program does not guarantee the quality of the services or procedures offered by the providers. Except for prescription drugs which you will pay directly to the pharmacy at the time of purchase, all other services received through a program provider will be charged to the credit card on file in your member account. The charge will include an administrative fee for use of the program. Towers Administrators LLC is the licensed discount medical plan organization with its administrative office located at 4510 Cox Road, Suite 111, Glen Allen, VA 23060. SingleCare Services, LLC is the marketer of the discount medical plan organization including its website, singlecare.com, with its corporate office located at 99 High Street, Suite 2800, Boston, MA 02110. For additional information, including an up-to-date list of providers, or assistance with any issue related to program membership, please contact member support any time at www.singlecare.com, or by calling toll-free 844-234-3057, 24 hours, 7 days a week (except major holidays). Pharmacy names, logos, brands, and other trademarks are the property of their respective owners.
Blog articles are not medical advice. They are intended for general informational purposes and are not meant to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. If you think you may have a medical emergency, immediately call your physician or dial 911.
© 2025 SingleCare Administrators. All rights reserved
© 2025 SingleCare Administrators. All rights reserved