Xaquil Xr is a brand-name prescription folate (vitamin B9) supplement used to treat depression along with antidepressants. Xaquil Xr works by breaking down an amino acid that, when levels are high, is linked to depression. The folate in Xaquil Xr is identical to vitamin B9 in the body, so it is readily absorbed and used by the body. Although the cash price of Xaquil Xr is $64.59, a SingleCare Xaquil Xr coupon significantly reduces this cost to $45.49. CVS, Walmart, Duane Reade, and other pharmacies accept SingleCare discount cards that can save you up to 80% on your prescription medications.
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SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.
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Prices updated: 12/05/2025
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Xaquil Xr is a brand-name prescription folate (vitamin B9) supplement used to treat depression along with antidepressants. Xaquil Xr works by breaking down an amino acid that, when levels are high, is linked to depression. The folate in Xaquil Xr is identical to vitamin B9 in the body, so it is readily absorbed and used by the body. Although the cash price of Xaquil Xr is $64.59, a SingleCare Xaquil Xr coupon significantly reduces this cost to $45.49. CVS, Walmart, Duane Reade, and other pharmacies accept SingleCare discount cards that can save you up to 80% on your prescription medications.
Xaquil Xr is a brand-name prescription folate (vitamin B9) supplement used to treat depression along with antidepressants. Xaquil Xr works by breaking down an amino acid that, when levels are high, is linked to depression. The folate in Xaquil Xr is identical to vitamin B9 in the body, so it is readily absorbed and used by the body. Although the cash price of Xaquil Xr is $64.59, a SingleCare Xaquil Xr coupon significantly reduces this cost to $45.49. CVS, Walmart, Duane Reade, and other pharmacies accept SingleCare discount cards that can save you up to 80% on your prescription medications.
Without insurance, customers can expect to pay $64.59 for Xaquil Xr, but this price may vary. With a SingleCare discount card, the cost of Xaquil Xr drops to $45.49 per 30, 25.5mg tablet extended releases.
As with any prescription drug copay, the cost of Xaquil Xr with insurance varies by plan. In fact, some insurance plans will not cover Xaquil Xr prescriptions because the active ingredient is available at a lower cost in generic, over-the-counter alternatives. Check with your pharmacist to see if your insurance covers Xaquil Xr. With SingleCare, Xaquil Xr costs as little as $45.49 for 30, 25.5mg tablet extended releases. This may be a better alternative to insurance, so have your pharmacist compare prices with your SingleCare discount card first before you overpay for Xaquil Xr.
Medicare-eligible patients are unlikely to get coverage on their Xaquil Xr prescription. Folate, the active ingredient, is available in cheaper, over-the-counter dietary supplements. Medicare patients can rely on their SingleCare Xaquil Xr coupon for consistent savings. Our free and reusable coupons are accepted at participating pharmacies.
Xaquil Xr is a brand-name prescription folate supplement. Folate is universally available in generic, over-the-counter dietary supplements. However, the folate used in Xaquil Xr is identical to the folate used in the body, so it can be immediately used by the body when absorbed. Many people have difficulty converting other folates, such as folic acid, into a useful version in the body. Check with your physician to determine what the best folate supplement is for your needs.
Xaquil Xr is a brand-name prescription folate (vitamin B9) supplement used to treat depression along with antidepressants. Xaquil Xr works by breaking down an amino acid, homocysteine, that, when levels are high, is linked to depression, dementia, and heart disease. The folate in Xaquil Xr is nearly identical to vitamin B9 in the body, so it is readily absorbed and used by the body.
Folate supplements alone do not improve depression. However, research shows that folate supplements may improve the effectiveness of antidepressants.
Xaquil Xr is taken as a 30 mg tablet once daily.
Common side effects of Xaquil Xr include but are not limited to gas, decreased appetite, nausea, and swelling.
Allergic reactions to the active ingredients are extremely rare and include rash and, more severely, chest spasms.
Mental and mood side effects are more common. Among these side effects are confusion, trouble sleeping, irritability, depression, and over-excitement.
SingleCare is accepted at most national pharmacies and grocers, including the following:
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