What is Xhance: Uses, Warnings & Interactions

Updated May 14, 2025  •  Published Dec 31, 2020

Xhance overview

BRAND NAMES:

  • Ticaspray, Veramyst, Leader Allergy Relief, Children's Flonase, ClariSpray, Flonase, Flonase Sensimist, FlutiCare, Good Sense 24-Hour Allergy, Health Mart Allergy Relief, Xhance, Sunmark Allergy Relief, Veramyst, Xhance

Generic Names:

  • Xhance

Uses:

  • Treats allergy symptoms (including runny or stuffy nose) and nasal polyps. This medicine is a corticosteroid.

Therapeutic Classes:

  • Corticosteroid, Strong, Anti-Inflammatory, Corticosteroid, Intermediate

Forms:

  • Spray

How it’s taken:

  • Into the nose

What is Xhance used for?

What form(s) does Xhance come in

  • Spray

What are common Xhance doses?

  • Box 16ML of 93MCG/ACT

Common Xhance prescriptions

  • Xhance
    16ml of 93mcg/act box

How to take Xhance

  • Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.

  • Nasal routeThis medicine is for use only in the nose. Do not get any of it in your eyes or on your skin. If it does get on these areas, rinse it off right away.

  • Shake the medicine well just before each use.

  • Fluticasone propionate and Veramyst®: Prime the new spray before using it for the first time. To prime, spray 6 times into the air away from the face, or pump the bottle until some of the medicine sprays out. Prime the spray if it has not been used for more than 7 days (or 30 days for Veramyst®) or if the cap has been left off the bottle for 5 days or longer.Nasal routeBefore using the medicine, gently blow your nose to clear the nostrils. Nasal routeAfter using the nasal spray, wipe the tip of the bottle with a clean tissue and put the cap back on.

  • Xhance„¢: Prime the new spray before using it for the first time. To prime, gently shake the bottle then spray 7 times into the air away from the face, or until some medicine comes out. If you have not used this medicine for 7 days or longer, prime it again by shaking and spraying 2 times into the air, away from the face.Insert the tip of the cone-shaped nosepiece deep into the nose to create a seal between the nosepiece and the nostril.Place the mouthpiece inside your mouth and blow on it. While blowing, push the bottle up to actuate the spray pump.Continue to blow through your mouth until the medicine is released, but do not inhale or exhale through the nose.Repeat in the other nostril for a full dose.

  • You may need to use this medicine for a few days before you start to feel better.

  • Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.

  • Follow the instructions on the medicine label if you are using this medicine without a prescription.

  • Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

  • Nasal routeKeep the bottle tightly closed when not using it. Store at room temperature, away from heat and direct light. Do not freeze or refrigerate. Throw this medicine away after you have used 120 sprays.

  • Nasal routeKeep the bottle tightly closed when not using it. Store at room temperature, away from heat and direct light. Do not freeze or refrigerate. Throw this medicine away after you use 120 sprays.

  • You may need to use this medicine for a few days before you start to feel better.

  • Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

  • Xhance„¢: Prime the new spray before using it for the first time. To prime, gently shake the bottle then spray 7 times into the air away from the face, or until some medicine comes out. If you have not used this medicine for 7 days or longer, prime it again by shaking and spraying 2 times into the air, away from the face.Insert the tip of the cone-shaped nosepiece deep into the nose to create a seal between the nosepiece and the nostril.Place the mouthpiece inside your mouth and blow on it. While blowing, push the bottle up to actuate the spray pump.Continue to blow through your mouth until the medicine is released, but do not inhale or exhale through the nose.Repeat in the other nostril for a full dose.

  • Nasal routeKeep the bottle tightly closed when not using it. Store at room temperature, away from heat and direct light. Do not freeze or refrigerate. Throw this medicine away after you use 120 sprays.

  • Follow the instructions on the medicine label if you are using this medicine without a prescription.

  • Nasal routeThis medicine is for use only in the nose. Do not get any of it in your eyes or on your skin. If it does get on these areas, rinse it off right away.

  • Fluticasone propionate and Veramyst®: Prime the new spray before using it for the first time. To prime, spray 6 times into the air away from the face, or pump the bottle until some of the medicine sprays out. Prime the spray if it has not been used for more than 7 days (or 30 days for Veramyst®) or if the cap has been left off the bottle for 5 days or longer.Nasal routeBefore using the medicine, gently blow your nose to clear the nostrils. Nasal routeAfter using the nasal spray, wipe the tip of the bottle with a clean tissue and put the cap back on.

  • Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.

  • Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.

  • Shake the medicine well just before each use.

  • Nasal routeKeep the bottle tightly closed when not using it. Store at room temperature, away from heat and direct light. Do not freeze or refrigerate. Throw this medicine away after you have used 120 sprays.

What to do if you miss a dose of Xhance

Xhance contraindications

  • This medicine is not right for everyone. Do not use if you had an allergic reaction to fluticasone.

Xhance warnings

  • Tell your doctor if you are pregnant or breastfeeding, or if you have liver disease, asthma, any infection (including tuberculosis, herpes infection of the eye), a recent exposure to measles or chickenpox, or a history of cataracts, glaucoma, or osteoporosis. Tell your doctor if you have had nose surgery, a nose injury, or a recent infection in your nose.

  • This medicine may cause the following problems:Holes, ulcers, or bleeding inside the noseIncreased risk of infectionSlow wound healingCataracts or glaucomaProblems with the adrenal glandsLow bone mineral density, which may lead to osteoporosisSlow growth in children

  • Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.

  • Call your doctor if your symptoms do not improve or if they get worse.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

  • Tiredness, weakness, dizziness

Xhance interactions

  • Do not use this medicine together with ritonavir.

  • Some medicines can affect how fluticasone works. Tell your doctor if you are using the following:Conivaptan, nefazodoneMedicine to treat HIV/AIDS (including atazanavir, indinavir, lopinavir, nelfinavir, saquinavir)Medicine to treat infection (including clarithromycin, itraconazole, ketoconazole, telithromycin, voriconazole)

  • Avoid people who are sick or have infections. Tell your doctor right away if you think you have been exposed to measles or chickenpox.

  • Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.

  • Call your doctor if your symptoms do not improve or if they get worse.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Xhance side effects

Serious Side Effects

  • Bone pain

  • Eye pain or vision changes

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Sores or white patches inside the nose or mouth

  • Dark freckles, skin color changes, coldness, weakness, tiredness, nausea, vomiting, weight loss

  • Heavy or unexplained bleeding from your nose, bleeding that will not stop

  • Burning, redness, swelling, or irritation around or inside your nose

  • Fever, chills, cough, sore throat, body aches

  • Tiredness, weakness, dizziness

Less Serious Side Effects

  • Headache

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