What is Xiaflex? Uses, warnings & side effects

How to take Xiaflex

• Your doctor will prescribe your exact dose and tell you how often it should be given. This medicine is given as a shot into your hand or penis.

• Injection routeA nurse or other health provider will give you this medicine.

• This medicine should come with a Medication Guide. Ask your pharmacist for a copy if you do not have one.

• Peyronie disease: Do not have sex or have any sexual activity between the first and second injections of a treatment cycle, and for at least 2 weeks after the second injection of a treatment cycle and after pain and swelling has gone away.

• Dupuytren contracture: Do not try to move or massage the cord, bend, or extend the fingers of the injected hand, or do heavy activity using your hand to prevent more injury.Your doctor may put a splint on your hand after giving this medicine. Wear the splint at bedtime for up to 4 months. Do finger bending and extending exercises as instructed by your doctor.

• This medicine should come with a Medication Guide. Ask your pharmacist for a copy if you do not have one.

• Dupuytren contracture: Do not try to move or massage the cord, bend, or extend the fingers of the injected hand, or do heavy activity using your hand to prevent more injury.Your doctor may put a splint on your hand after giving this medicine. Wear the splint at bedtime for up to 4 months. Do finger bending and extending exercises as instructed by your doctor.

• Your doctor will prescribe your exact dose and tell you how often it should be given. This medicine is given as a shot into your hand or penis.

• Injection routeA nurse or other health provider will give you this medicine.

• Peyronie disease: Do not have sex or have any sexual activity between the first and second injections of a treatment cycle, and for at least 2 weeks after the second injection of a treatment cycle and after pain and swelling has gone away.

What to do if you miss a dose of Xiaflex

Xiaflex contraindications - Who shouldn't take Xiaflex?

• This medicine is not right for everyone. You should not receive it if you had an allergic reaction to collagenase, Clostridium histolyticum, or if you have Peyronie plaque in the penile urethra.

Xiaflex warnings

• Tell your doctor if you are pregnant or breastfeeding, or if you have a blood clotting problem.

• This medicine may cause the following problems:Tendon rupture or other serious injury to the affected finger or handFracture of or other serious injury to the penisBleeding or bruising at the injection site

• Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.

• Severe bruising or bleeding at the injection site

• Peyronie disease: Popping sound or sensation in an erect penis, sudden loss of an erection or painful erection, blood in your urine or trouble urinating

Xiaflex interactions & what to avoid when taking Xiaflex

• Some medicines can affect how collagenase, Clostridium histolyticum works. Tell your doctor if you are using blood thinners (including high-dose aspirin or warfarin).

• This medicine may cause the following problems:Tendon rupture or other serious injury to the affected finger or handFracture of or other serious injury to the penisBleeding or bruising at the injection site

• Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.