Does Zoloft make you gain weight?

Zoloft may cause weight gain, especially with long-term use. Weight changes vary by individual, with some people gaining and others losing weight. This is primarily because Zoloft can increase appetite and improve depressive symptoms, which may normalize or increase eating, though short-term use has been associated with slight weight loss in some studies.

Want to dive deeper?  Read our full analysis: Does Zoloft cause weight gain?

Medical disclaimer: This content is for general informational purposes only and does not constitute medical advice. Always consult your healthcare provider before making changes to your medication regimen.

Sources

• Real-world data on SSRI antidepressant side effects, Psychiatry (2009)

• Long-term weight change after initiating second-generation antidepressants, Journal of Clinical Medicine (2016)