Key takeaways
NovoLog (insulin aspart) is a rapid-acting insulin used to control blood sugar in people with diabetes.
Without insurance, NovoLog costs about $595 for a box of five 3 mL pens containing 100 units/mL.
People without insurance may be able to lower the cost of NovoLog with a SingleCare discount card, manufacturer savings programs, or lower-cost insulin alternatives.
NovoLog (insulin aspart) is a prescription rapid-acting insulin used to help control blood sugar. Without insurance, NovoLog costs about $595 for one box of five 3 mL pens containing 100 units/mL. The amount of insulin needed varies by person, so how long one pen lasts will depend on the prescribed dose.
NovoLog is available in prefilled injection pens, cartridges, and vials. People paying for NovoLog without insurance may be able to reduce their out-of-pocket costs with prescription discounts, manufacturer programs, or other insulin options.
Related: NovoLog FlexPen dosage | NovoLog FlexPen side effects
What is the generic for NovoLog?
NovoLog is Novo Nordisk’s brand-name formulation of rapid-acting insulin. Its active ingredient is insulin aspart. Novo Nordisk previously sold an unbranded insulin aspart product equivalent to NovoLog, but the company discontinued its unbranded biologic insulins on Dec. 31, 2025.
There are, however, two lower-priced FDA-approved insulin aspart biosimilars to NovoLog: Merilog (insulin aspart-szjj) and Kirsty (insulin aspart-xjhz). Kirsty is designated as interchangeable with NovoLog, meaning a pharmacist may be able to substitute it for NovoLog without a new prescription, depending on state law. Merilog does not have an interchangeable status and will require a new prescription from the healthcare provider.
A third biosimilar, Garzulys (insulin aspart-fsan), was approved in July 2026.
Other rapid-acting insulin options include Sanofi’s Admelog (insulin lispro) and Apidra (insulin glulisine), Eli Lilly’s Humalog (insulin lispro) and Lyumjev (insulin lispro-aabc), and Novo Nordisk’s Fiasp (insulin aspart).
RELATED: NovoLog FlexPen alternatives
Is NovoLog covered by insurance?
NovoLog may be covered by private insurance, Medicare Part D, and Medicaid, but coverage and copays vary by plan. Health insurance plans have their own deductibles, formularies, and preferred medications, so check your plan to confirm whether NovoLog is covered and what you may pay out of pocket.
In 2023, Novo Nordisk, Eli Lilly, and Sanofi announced significant reductions in the list prices and out-of-pocket costs of several insulin products. For people with Medicare, the Inflation Reduction Act limits the cost of each covered insulin product to no more than $35 for a one-month supply. NovoLog FlexPen, if covered by the plan, would generally be covered under Part D because Medicare Part B covers insulin used with certain covered insulin pumps rather than insulin administered with a pen. Out-of-pocket costs under Medicaid vary by state and eligibility.
How much does NovoLog cost without insurance?
The average retail cash price of one box of five 3 mL NovoLog FlexPen containing 100 units/mL is approximately $595. How long one box of pens lasts depends on the dose prescribed
Using a SingleCare discount card, the price of the same box of NovoLog FlexPens can be as low as $121, a savings of nearly $475 per box.
RELATED: NovoLog savings guide
Compare NovoLog prices to related drugs |
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|---|---|---|---|
| Drug name | Price without insurance of brand-name drug | SingleCare price | Savings options |
| NovoLog FlexPen (insulin aspart) | $595 for 1 box of five 3 mL of 100 units/mL pen | $121 for 1 box of five 3 mL of 100 units/mL pen of brand-name NovoLog FlexPen at Kroger | See latest prices |
| Humalog (insulin lispro) | $580 for 1 box of five 3 mL of 100 units/mL pen | $158 for 1 box of five 3 mL of 100 units/mL pen of generic Humalog at Kroger | See latest prices |
| Fiasp (insulin aspart) | $1,105 for 3, 10 mL of 100 units/mL vials | $187 for 3, 10 mL of 100 units/mL vials of brand-name Fiasp at Kroger | See latest prices |
| Apidra (insulin glulisine) | $290 for 1, 10 mL of 100 units/mL vial | $85 for 1, 10 mL of 100 units/mL vial of brand-name Apidra at Kroger | See latest prices |
| Admelog (insulin lispro) | $178 for 1, 10 mL of 100 units/mL vial | $26 for 1, 10 mL of 100 units/mL vial of generic Admelog at Kroger | See latest prices |
How to get NovoLog without insurance
There are several ways to avoid paying the full price for NovoLog without insurance. Here are some ways to save money on NovoLog:
1. Use a SingleCare savings card
Using a SingleCare discount card can significantly reduce the cash price of NovoLog. For example, NovoLog FlexPen can cost as little as $121 for one box of five 3 mL, 100 units/mL pens, compared with an average cash price of $595 for the same quantity. SingleCare is free to use and available to anyone with a valid prescription. Registered members may save even more, and it is free to sign up.
2. Check Novo Nordisk savings programs
Novo Nordisk offers affordability programs for eligible patients who need insulin. Through MyInsulinRx, eligible uninsured patients may pay $35 for a monthly supply of covered Novo Nordisk insulin products. Eligibility requirements and other restrictions apply.
3. Consider a different insulin brand
ReliOn NovoLog is a private-label version of NovoLog manufactured by Novo Nordisk and sold through Walmart pharmacies. It may cost less than brand-name NovoLog. Ask your healthcare provider whether a lower-cost insulin option is appropriate for you.
4. Shop pharmacies for the best price
Insulin prices can vary by pharmacy. Compare the cash price of NovoLog at several pharmacies before filling your prescription. SingleCare makes this easy to do online or on the go with the SingleCare app.
RELATED: Diabetes coupons & discount diabetes supplies
The SingleCare prices in this article are the most accurate at the time of publishing in ZIP code 23666 as of Sep. 23, 2026. Prices vary by pharmacy. Visit our coupon page for updated drug prices at pharmacies near you.
- NovoLog insulin aspart injection prescribing information, DailyMed (NIH National Library of Medicine) (2023)
- Taking NovoLog, Novo Nordisk (2026)
- Discontinuation notice, Novo Nordisk (2024)
- Kirsty, Biocon Biologics (2026)
- In brief: Merilog—a NovoLog biosimilar, The Medical Letter (2025)
- All 3 major insulin manufacturers are cutting their prices—here’s what the news means for patients with diabetes, JAMA (2023)
- Insulin, Medicare.gov
- Walmart revolutionizes insulin access & affordability for patients with diabetes with the launch of the first and only private brand analog insulin, Walmart (2021)
- Meitheal Pharmaceuticals announces FDA approval of Garzulys, Meitheal Pharmaceuticals (2026)
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