Fitness Supplements

Cropped SingleCare logo By | February 18, 2019

The business of vitamins and supplements is booming. Recent research suggests that most Americans take at least one such product from the more than 90,000 options on the market. But within this massive industry – worth $37 billion by some estimates – consumer enthusiasm is dampened by uncertainty. In the absence of strict regulation, many manufacturers peddle wares with few real benefits. Worse still, dangerous outcomes are increasingly common. The American Association of Poison Control Centers report a troubling rise in incidents resulting from supplement consumption. Which vitamins and supplements are really worth taking, and which might not give you much support as you work toward your fitness goals?

Putting aside the sometimes bold claims found on supplement bottles, we set to survey around 1,000 individuals about their real experiences with a range of products. Our findings reveal which products actually produce results for individuals at various fitness levels and with different body types. Additionally, we uncovered common supplement side effects, presenting a clearer picture of the potential trade-offs. Whether you’re beginning a new diet and fitness regimen or are looking for new products to support an established routine, you won’t want to miss what we discovered.

Essential Supplements by Fitness Experience

Some fitness pros swear by complex combinations of vitamins and supplements (often called a “stack”), but beginners may feel most comfortable starting with a single product. If you’re turning a new leaf in terms of diet and exercise – a New Year’s resolution, perhaps – you’ll want to know which supplements our respondents considered most essential (to find out more about what each supplement is used for, jump down to the glossary).

Men and women were most likely to identify whey protein as an essential supplement, perhaps because it’s associated with broadly shared fitness goals, such as increasing strength and muscle size. Caffeine was also highly regarded by both genders. While many people consume it as a matter of habit each morning, the chemical found in coffee can improve workout performance as well.

Men and women differed in their views of other supplements, however. Men were far more likely to view creatine as essential, for example, whereas a greater percentage of women said sleep supplements and fat burners were fundamental to their routines.

Fitness experience also seemed to influence supplement preference. Respondents who identified as “advanced” fitness enthusiasts had a particular penchant for pre-workout in comparison to other fitness levels. It may be wise for fitness novices to steer clear. Experts say that pre-workout users can flood their systems with alarming amounts of sugar, caffeine, and other stimulants if they opt for the wrong product or dosage.

Assessing Effectiveness

Of those who try each supplement, what percentage of individuals actually achieves the results they desire? Pre-workout and whey protein had the highest percentage of people reporting success, with approximately 6 in 10 users findings these supplements very or extremely effective. Respondents also reported high success rates with vegetable protein and branched-chain amino acids (BCAAs). If our findings suggest most people find these protein-centric products helpful, the same could not be said of supplements designed to eliminate fat. Just 41 percent of those who took fat burners found them very or extremely effective; experts say deceptive marketing is particularly rampant in this segment of the supplement industry.

Interestingly, respondents who regarded themselves as fitness beginners were less likely to find supplements effective overall. Conversely, the advanced fitness cohort was most likely to find supplements effective. These findings likely relate to one of exercise’s painful ironies: Experienced athletes often enjoy visible gains more quickly than beginners. With a new weightlifting routine, for example, experts find that experienced lifters see muscle growth in three to four weeks, whereas novices typically won’t notice improvement for two months. Because our respondents quit using supplements after 4.5 weeks, on average, it’s no wonder beginners tend to find them less effective.

Favorites by Physique

Diet and fitness goals differ enormously by body type, and respondents with various physiques found certain supplements effective for their own goals. Those who identified as ectomorphs or “somewhere in between” found protein varieties most effective, with more than 60 percent of respondents in these categories finding whey and vegetable proteins helpful. At the other end of the spectrum, pre-workout was the biggest hit for mesomorphs and endomorphs’ burlier body types. Additionally, 62.5 percent of mesomorphs found creatine effective, a significantly higher success rate than other body types. Designed to support short bursts of speed or strength, creatine would logically appeal to those who already possess a healthy baseline of muscle.

Supplements didn’t always seem to work for those who needed them most, however. Endomorphs, who can struggle to lose weight, were the least likely to find fat burner supplements effective. This finding underscores the complex nature of achieving fitness goals: For many, diet, exercise, and supplements must work in concert to produce lasting change, and even then, progress can prove frustratingly slow. Indeed, almost 64 percent of respondents regarded diet and exercise as equally important for achieving fitness outcomes.

Unintended Outcomes

Aside from the gains they sought from particular products, a quarter of respondents experienced another supplement outcome: side effects. Caffeine was the most likely to produce unwanted effects, which can include headaches, shakiness, and insomnia. A quarter of whey protein users also reported side effects; many who take it report gastrointestinal issues. Moderating how much one consumes may mitigate these symptoms. One survey respondent described indigestion after taking whey protein but attributed it to his inexperience gauging the right amount.

Pre-workout, which typically includes several sources of side effects, can also produce unpleasant symptoms. One respondent told us pre-workout made his heart “palpitate like crazy,” which could be attributable to massive amounts of caffeine these products typically entail. Fat burners also caused side effects for a large percentage of users – and some negative outcomes in this category surpass temporary discomfort. From elevated blood pressure to liver damage requiring hospitalization, the side effects of unregulated fat burners often cause lasting damage.

Supplement Information Sources

If supplement effectiveness is uncertain, and unpleasant side effects are common, consumers have plenty of reasons to do their research before trying a new product. Advanced fitness types were the most likely to rely on online reviews to guide their supplement selection, although this was the most common source of information for all respondents. Experienced athletes also trusted tips from trainers and fitness celebrities, an ever-expanding presence on Instagram. Beginners, conversely, were the most apt to trust recommendations from friends and online forums.

Interestingly, only about 1 in 10 respondents at each fitness level said they were swayed by social media advertisements. Yet, ads for vitamins and supplements abound on Instagram and other platforms, both through paid posts and less conspicuous plugs by influencers – many making unfounded claims. Of course, doctors can help evaluate the potential benefits of a given product, but just 30 percent of beginners and intermediate exercisers consulted medical professionals, and advanced athletes were even less likely to do so. Experts say visiting a doctor before starting a supplement is essential for those with chronic illnesses, because new products may exacerbate their conditions or counteract their current medications.

Staying Well While Saving

While our findings suggest that many people benefit significantly from consuming supplements, there are plenty of reasons to be cautious when considering new products. From unfortunate side effects to no effects whatsoever, disappointing outcomes are exceedingly common. Perhaps these findings reinforce the oldest premise of diet and exercise: There is no single, swift solution. Rather, success depends on realistic goals and incremental improvement in several areas. Supplements may help you achieve your health and fitness ambitions, but they’re unlikely to do so alone.

Health care is one important dimension of supporting your well-being, and your medical needs are too important to ignore. Yet, many Americans delay filling essential prescriptions, simply because the medicines they need are so expensive. Let SingleCare show you a better way to wellness, offering you discounts on prescriptions and transparent price information for pharmacies in your area. It’s free to sign up, and our app makes getting your discounts easy. Learn about how we can help you afford the care you deserve today.


For this study, we surveyed 999 fitness supplement users who exercised at least once a week. 49.1% were men, and 50.9% were women. Less than 1% were nonbinary. 8.2% considered themselves to be at an advanced fitness level, 61.2% were intermediate, and 30.6% reported that they were at a beginner fitness level. 25.3% described their body type as endomorphic, 16.5% were ectomorphic, and 23.1% were mesomorphic. About 35% said they were a mixture of one or more types. On average, participants were 35.1 years of age with a standard deviation of 10.9. Their ages ranged from 18 to 74.


Data and findings were not statistically tested nor weighted. Our analysis was by no means exhaustive of all possible fitness-related supplements. The supplements included in this analysis were chosen based on research and crowdsourcing a list of the most popular supplements. Only supplements with a sample size of at least 26 were included in our visualizations. If we had included more or different supplements, our findings may have varied greatly. There are also inherent weaknesses in using self-reported data, such as poor recall or incorrect memory, over-exaggeration, selective reporting, and underrepresentation.



Fair Use Statement

The world could use more clear and unbiased information about supplements, so we hope you’ll share our findings with others. If you’d like to cite our information or use our graphics, you’re welcome to do so for noncommercial purposes. Just link back to this page when you do, so more people can get the full scoop on all the supplements included in our study.

Supplement Glossary

Beta-AlanineBeta-alanine is an amino acid used for improving athletic performance and exercise capacity and building lean muscle mass.https://www.webmd.com/vitamins/ai/ingredientmono-1222/beta-alanine
BCAAs (Branched-Chain Amino Acids)Branched-chain amino acids (BCAAs) are a group of three essential amino acids: leucine, isoleucine, and valine. BCAAs have been shown to build muscle, decrease muscle fatigue, and alleviate muscle soreness.https://www.healthline.com/nutrition/benefits-of-bcaa#section3
CaffeineCaffeine can increase alertness, sharpen focus, improve mood, improve tolerance for pain caused by exercise, help burn fat, and increase stamina.https://www.bodybuilding.com/content/boost-your-workout-with-caffeine.html
CreatineCreatine is a naturally occuring substance found in meats and seafood that is commonly used for improving exercise performance and increasing muscle mass.https://www.webmd.com/vitamins/ai/ingredientmono-873/creatine
Conjugated Linoleic Acids (CLAs)**Conjugated linoleic acids help reduce body fat deposits and improve immune function. CLAs are known to help your body build muscle rather than store fat.https://www.webmd.com/vitamins/ai/ingredientmono-826/conjugated-linoleic-acid
EAAs (Essential Amino Acids)EAAs are vital for muscle tissue development and cell repair during recovery. If you fail to consume sufficient amounts of EAAs, your body can’t optimize the nutrients from protein sources that you consume.https://www.myokem.com/blog/benefits-bcaas-and-eaas-guide-amino-acid-supplements/
EphedrineBefore being banned by the FDA in 2003, ephedrine was a popular component of over-the-counter weight loss drugs. It can increase weight and body fat loss, improve athletic performance, and improve concentration.https://www.webmd.com/diabetes/qa/what-is-ephedrine
Fat burnersFat burner supplements are claimed to acutely increase fat metabolism or energy expenditure, impair fat absorption, increase weight loss, and increase fat oxidation during exercise.https://www.phd-supplements.com/news/blog/2017/07/17/what-are-fat-burners-and-how-do-they-work/
GlucosamineGlucosamine plays a vital role in building cartilage. The main purpose of glucosamine is to create long chains called glycosaminoglycans (GAGs), which help repair cartilage and joints.https://www.bodybuilding.com/fun/glucosamine.htm
GlutamineGlutamine is an amino acid that is produced in the muscles and is distributed by the blood to the organs that need it. Glutamine might help gut function, the immune system, and other essential processes in the body, especially in times of stress.https://www.webmd.com/vitamins/ai/ingredientmono-878/glutamine
Intraworkout SupplementsAn intraworkout supplement is a supplement you take to help support endurance, replenish essential nutrients, and increase your muscle mass during your workout. It can include BCAAs, leucine, taurine, and electrolytes.https://www.asd-performance.com/blogs/articles/the-benefits-of-intra-workout-supplements-bcaas
Mass GainerA mass gainer is a supplement that provides protein, carbohydrates, and possibly fats with the intention of helping to add muscle mass. It is a high-calorie protein powder aimed at increasing your daily calorie intake to promote weight gain.https://us.myprotein.com/thezone/supplements/what-is-a-mass-gainer/
Nitric OxideNitric oxide is a gas that’s made by your body, and it is used to promote vasodilation, or increased blood flow.https://www.menshealth.com/health/a19717792/nitric-oxide-supplements/
Sleep supplementNatural sleep aids to treat insomnia include valerian, chamomile, and melatonin.https://www.webmd.com/sleep-disorders/features/sleep-supplements-herbs#1
Sodium bicarbonate (baking soda)Taking sodium bicarbonate (NaHCO₃) before exercise helps to flush metabolic byproducts from the muscle tissue produced during high-intensity workouts.https://www.verywellfit.com/how-baking-soda-can-improve-athletic-performance-4057192
Soy proteinLike whey and vegetable proteins, soy is also used to build muscle mass and size and is a vegan alternative to whey protein powder.https://www.bodybuilding.com/fun/soy_protein_facts.htm
Tart cherry juiceTart cherry juice intake may reduce muscle strength loss and soreness. It may also speed up recovery and reduce symptoms of insomnia.https://www.healthline.com/nutrition/10-tart-cherry-juice-benefits#section3
Vegetable ProteinVegetable protein is used to increase muscle size and lean body mass but is made of complete vegetable proteins from peas, rice, or other vegetables.https://www.bodybuilding.com/fun/wheys-vegan-alternatives-combining-pea-and-rice-protein.html
Whey ProteinSeveral studies have found that whey protein, when combined with strength training, might increase strength, muscle size, and lean body mass.https://www.webmd.com/diet/supplement-guide-whey-protein