Humira generic availability, cost, and dosage

In this article:

• Is there a generic for Humira?
• Humira vs. biosimilars
• Humira (and biosimilars) at a glance
• How much is a Humira biosimilar?
• Is Humira covered by insurance?
• How do you get Humira covered by insurance?
• Less expensive alternatives to Humira
• Expert takeaway

In this article

• Is there a generic for Humira?
• Humira vs. biosimilars
• Humira (and biosimilars) at a glance
• How much is a Humira biosimilar?
• Is Humira covered by insurance?
• How do you get Humira covered by insurance?
• Less expensive alternatives to Humira
• Expert takeaway

Humira is an injectable prescription drug made by the drug company AbbVie, Inc. It works by blocking the effects of tumor necrosis factor (TNF), a chemical messenger that causes inflammation. Although some prescription medications have generic versions that are often more affordable, Humira has “biosimilars” instead. Here’s what to know about your options. 

Is there a generic for Humira?

Yes, but it isn’t technically called a “generic.” Traditional generics are less expensive copies of FDA-approved drugs. The active ingredient in Humira is adalimumab, and there are different, less expensive versions of adalimumab out there. But instead of calling those versions “generics,” they’re called biosimilars. That’s because Humira is a biologic drug. 

Biologics come from natural sources, such as humans or animals. They’re very complex and difficult to duplicate exactly. As such, a biosimilar product is a highly similar, but not identical, version of an FDA-approved biologic drug.  

Humira has a high price tag, but several lower-cost FDA-approved biosimilars of Humira (adalimumab) are available under their own names. Some biosimilars also have an interchangeability designation, which means that a prescription for Humira can, if allowed by state law, be filled with an interchangeable biosimilar. Biosimilars that are not designated as interchangeable must be prescribed by exact name, because they cannot be substituted for Humira.

What are the differences between brand-name and generic Humira (biosimilars)?

Because biologics are complex, a biosimilar cannot be exactly the same as the reference product (or brand-name drug). However, biosimilars contain the same active ingredient, work the same way, and have the same mode of administration (such as injection) and dosing as the reference product. Humira and its biosimilars are approved to treat the same conditions, but some biosimilars have different FDA approvals in terms of age. There are also other differences to consider. For example, there are low-concentration formulation and high-concentration formulation options, which can affect how much liquid is injected and patient comfort. 

How much is a Humira biosimilar?

The typical price without insurance or discounts for a one-month supply of Humira is about $9,092. However, if you use a Humira biosimilar, you could save a significant amount of money on your prescription. For example, a one-month supply of the biosimilar Hyrimoz costs about $2,002, but if you use a SingleCare discount at a participating pharmacy, you can pay $1,259 for your prescription. Prices may vary depending on your dosage, quantity prescribed, and the pharmacy where you fill your prescription. Humira is often filled at a specialty pharmacy because biologics are considered specialty drugs and require special handling.

Prescription drug prices often change. These are the most accurate medication prices at the time of publishing in ZIP code 23666 as of Feb. 13, 2026. The listed price without insurance references the price of brand-name drugs (unless otherwise specified). The listed SingleCare price references the price of generic drugs if available. 

Is Humira covered by insurance?

It is best to check with your specific health insurance company to see whether they cover Humira or a biosimilar. The manufacturer’s website for Humira offers assistance from insurance specialists who can help you and your healthcare provider determine whether your health plan covers Humira and any required steps (such as prior authorization), as well as ways to save on Humira and other resources to navigate insurance. 

If your insurance does not cover brand-name Humira, it may cover a biosimilar version. Your healthcare professional can help you navigate this process.

If you are paying without insurance or your insurance plan does not cover Humira, you can learn more about paying for Humira without insurance.

How do you get Humira covered by insurance?

Many insurance plans cover Humira or a biosimilar, but coverage often requires a prior authorization. With prior authorization, your healthcare provider needs to submit additional information to your insurance plan about why you need a specific medication. Your healthcare provider can help determine whether your plan covers Humira or a specific biosimilar and complete the required steps to help you fill your prescription. If you want to check your coverage ahead of time, you can contact your insurance provider directly or sign in to your account on your plan’s website to look up the most current formulary (list of covered drugs and their pricing tiers). 

Less expensive alternatives to Humira

The good news is that if your insurance does not pay for Humira, there are several options in terms of biosimilars that your insurance may cover. Some are interchangeable biosimilar products, which means your healthcare provider can write the prescription for Humira, and the pharmacy can substitute an interchangeable biosimilar. Others are biosimilar but not interchangeable, so your healthcare provider would have to specify the product by name. Examples of Humira biosimilars include Cyltezo, Hyrimoz, and Hadlima.

If you are interested in exploring other alternatives to Humira that do not contain the same active ingredient, there are other options to consider. You can discuss Humira alternatives with your healthcare provider, as well as the best way to switch. Only your healthcare provider can determine which medication is best for you based on individual considerations. 

Expert takeaway  

“Adalimumab biosimilars are less expensive treatment options for the blockbuster drug Humira, but there are many considerations to take into account, including insurance coverage, reason for use, and age of the patient,” says Karen Berger, Pharm.D., member of the SingleCare Medical Board. “Talk to your healthcare provider to find the best treatment for you.” 

The SingleCare prices in this article are the most accurate at the time of publishing in ZIP code 23666 as of Feb. 13, 2026. Prices vary by pharmacy. Visit our Humira coupon page for updated Humira prices near you.