AIRSUPRA is the first FDA-approved rescue inhaler that prevents asthma attacks and treats asthma symptoms as needed. It is made up of a combination of albuterol (a short-acting beta-2 agonist) and budesonide (a corticosteroid). If a paradoxical bronchospasm (worsening of breathing or increased wheezing) or hypersensitivity reaction occurs, stop using AIRSUPRA and seek medical help.
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AIRSUPRA
Albuterol-budesonide (not available for sale as a generic medication)
Prevent asthma attacks
Inhalation aerosol
Inhaled by mouth
AIRSUPRA is approved for adults ages 18 years and older. It should be used as needed to prevent asthma attacks and treat asthma symptoms. It should not replace maintenance medication for asthma.
AIRSUPRA should not replace maintenance asthma treatments. Do not stop taking any other maintenance medications without speaking to your healthcare provider.
Take AIRSUPRA as prescribed. Do not take more than 12 inhalations per day because it could be fatal.
Before starting AIRSUPRA, tell your healthcare provider about all medical conditions that you have, any other medications that you take, and any infections that you may have or be at risk of getting.
When you first use your AIRSUPRA inhaler, write a use-by date on the actuator label with permanent ink. The use-by date should be 12 months after opening the foil pouch.
If possible, rinse your mouth with water after an AIRSUPRA dose and spit it out in order to reduce the risk of getting a fungal infection. Do not swallow the water.
Inhalation aerosol:
10.7 gm of albuterol 90 and budesonide 80 mcg per actuation
2 inhalations as needed
Do not exceed 12 inhalations in 24 hours
Airsupra
10.7gm of 90-80mcg/act (120 inhalations) inhaler
Consult a healthcare professional to learn how to use the inhaler correctly. Read all of the instructions before using it for the first time.
Use AIRSUPRA exactly as your healthcare provider tells you to use it.
Do not use AIRSUPRA more often than prescribed (no more than 12 puffs within a 24-hour period).
Do not change or stop other asthma medications or inhalers without consulting your healthcare provider.
AIRSUPRA is not intended to be used daily or as a maintenance medication, so there are no adverse events related to a missed dose. Use AIRSUPRA on an as-needed basis.
Do not use AIRSUPRA if you are allergic to its ingredients (albuterol sulfate, budesonide, or inactive ingredients).
AIRSUPRA is only approved for adults ages 18 years and older.
Tell your doctor if you have any of the following health conditions before using AIRSUPRA:
Heart problems
High blood pressure
Seizures
Thyroid problems
Diabetes
Low potassium levels
Immune system problems
Tuberculosis of the respiratory tract (current or previous infection)
Any untreated infection (including viral, bacterial, parasitic, fungal, or herpes simplex infection of the eye)
Exposure to chickenpox or measles or if you have not been vaccinated against these diseases
Weak bones or risk factors for weak bones
Eye problems (increased pressure, glaucoma, cataracts)
Liver problems
Pregnant or planning to become pregnant
Breastfeeding
Tell your doctor if you take any of the following medications before using AIRSUPRA:
CYP3A4 inhibitors
Other inhaled medicines
Other asthma medicines
Beta blockers
Diuretics
Digoxin
Monoamine oxidase inhibitors
Tricyclic antidepressants
Report any side effects that are bothersome or will not go away to your healthcare provider. Make sure to report if your breathing problems get worse, you need to use AIRSUPRA more often than usual, or AIRSUPRA does not work as well to relieve your asthma as it did before. Seek medical help right away if you experience paradoxical bronchospasm or a severe allergic reaction after taking a dose of AIRSUPRA.
Serious side effects:
Worsening trouble breathing, coughing, and wheezing (paradoxical bronchospasm)
Fast heart rate
Increased blood pressure
Low levels of potassium (hypokalemia)
Weakened immune system and increased chance of infection
Oral thrush
Adrenal insufficiency
Osteoporosis
Eye problems, such as glaucoma and cataracts
Less serious side effects:
Headache
Cough
Hoarseness
AIRSUPRA patient information, U.S. Food and Drug Administration (2023)
About AIRSUPRA, AstraZeneca (2023)
Highlights of prescribing information, AstraZeneca (2023)
Josephine Bawab, Pharm.D., graduated from Virginia Commonwealth University School of Pharmacy. She began working in community pharmacy in 2012 and has worked for multiple chain pharmacies since then. She is passionate about helping patients and precepting students. She currently works and resides in Virginia, where she is just a few minutes away from the beach.
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