What is Aldurazyme: Uses, Warnings & Interactions

Updated May 14, 2025  •  Published Apr 11, 2021

Aldurazyme overview

BRAND NAMES:

  • Aldurazyme

Generic Names:

  • Aldurazyme

Uses:

  • Treats mucopolysaccharidosis I (MPS I).

Therapeutic Classes:

  • Endocrine-Metabolic Agent, Enzyme Replacement

Forms:

  • Injectable

How it’s taken:

  • By injection

What is Aldurazyme used for?

Aldurazyme indicated for long-term enzyme replacement associated with a genetic condition called mucopolysaccharidosis or MPS I. Aldurazyme contains an enzyme that occurs naturally in the body of healthy people.

What form(s) does Aldurazyme come in

  • Injectable

What are common Aldurazyme doses?

  • Vial 5ML of 2.9MG/5ML

Common Aldurazyme prescriptions

  • Aldurazyme
    5ml of 2.9mg/5ml vial

How to take Aldurazyme

  • Injection routeYour doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein.

  • Injection routeA nurse or other health provider will give you this medicine.

  • This medicine is usually given once a week. The medicine is injected slowly, so the needle will remain in place for 3 to 4 hours.

  • Missed dose: You must use this medicine on a fixed schedule. Call your doctor or pharmacist if you miss a dose.

What to do if you miss a dose of Aldurazyme

Aldurazyme contraindications

  • This medicine is not right for everyone. You should not receive it if you had an allergic reaction to laronidase.

Aldurazyme warnings

  • Tell your doctor if you are pregnant or breastfeeding, or if you have heart disease, lung disease or breathing problems, you use oxygen, or you have an infection or illness.

  • Chest pain, swelling in your hands, ankles, or feet

  • Fast, slow, pounding, or uneven heartbeat

  • Fever, chills, cough, sore throat, runny or stuffy nose

  • Lightheadedness or fainting

  • Numbness, tingling, or burning pain in your hands, arms, legs, or feet

  • Trouble breathing, rapid or shallow breathing

  • Unusual bleeding, bruising, or weakness

Aldurazyme interactions

  • Tell your doctor if you are pregnant or breastfeeding, or if you have heart disease, lung disease or breathing problems, you use oxygen, or you have an infection or illness.

Aldurazyme side effects

Serious Side Effects

  • Unusual bleeding, bruising, or weakness

  • Lightheadedness or fainting

  • Numbness, tingling, or burning pain in your hands, arms, legs, or feet

  • Trouble breathing, rapid or shallow breathing

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Chest pain, swelling in your hands, ankles, or feet

  • Fast, slow, pounding, or uneven heartbeat

  • Fever, chills, cough, sore throat, runny or stuffy nose

Less Serious Side Effects

  • Rash or itching

  • Headache

  • Warmth or redness in your face, neck, or chest

  • Pain, itching, burning, swelling, or a lump under your skin where the needle is placed

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